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Mashup Score: 0
MBS is an effective and well tolerated treatment for adolescents with severe obesity resulting in substantial weight loss and improvements in several aspects of metabolic health and physical quality of life over 2 years, and should be considered in adolescents with severe obesity.
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Mashup Score: 0
In this RCT, treatment with methylprednisolone in children with PIMS-TS did not significantly affect the length of hospital stay compared with intravenous immunoglobulins. Intravenous methylprednisolone could be an acceptable first-line treatment in children with PIMS-TS.
Categories: Latest Headlines, RheumatologyTweet
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Mashup Score: 6Adolescent acne vulgaris: current and emerging treatments - 1 year(s) ago
Acne vulgaris is one of the commonest inflammatory skin diseases seen worldwide, affecting all ethnicities and races, with a peak prevalence between age 15 years and 20 years. The burden of this condition, and the resulting clinical and psychological sequelae, is substantial. The visual appearance of acne and its sequelae, including scarring and pigment changes, frequently results in…
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Mashup Score: 3
NeoCLEAR is the largest trial investigating paediatric lumbar puncture so far. Success rates were improved when sitting rather than lying. Sitting lumbar puncture is safe, cost neutral, and well tolerated. We predominantly recruited term neonates younger than 3 days; other populations warrant further study. Neonatal lumbar puncture is commonly performed worldwide; these results therefore strongly…
Categories: Latest Headlines, PediatricsTweet
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Mashup Score: 1Water insecurity: an urgent threat to child health - 1 year(s) ago
Intensifying drought in the Horn of Africa throughout 2022 doubled the number of children facing severe thirst, hunger, and disease—from 10 million to 20·2 million—between July and December. The current drought, the region’s worst in 40 years, has also facilitated the spread of infectious diseases, including the re-emergence of cholera in Somalia, Ethiopia, and Kenya. Beyond the region, the lack…
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Mashup Score: 22Newborn screening for spinal muscular atrophy in Australia: a non-randomised cohort study - 1 year(s) ago
Newborn screening for SMA, coupled with early access to disease-modifying therapies, effectively ameliorates the functional burden and associated comorbidities for affected children. For children diagnosed through newborn screening, motor score, CMAP, and disease status at diagnosis has clinical utility to determine functional independence.
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Mashup Score: 22The high cost of living for children in the UK - 1 year(s) ago
The shocking inquest findings on 2-year-old Awaab Ishak’s death in December, 2020, from a respiratory condition caused by prolonged exposure to mould in his home have highlighted the dire living conditions of many children in the UK. Concluding the inquest on Nov 15, the coroner noted poor ventilation as a contributory factor, as well as an insufficient response by the housing association…
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Mashup Score: 0Pragmatic trials for critical illness in neonates and children - 1 year(s) ago
More than 100 000 infants and children are admitted to neonatal and paediatric intensive care units in the UK annually. Infections and sepsis remain a leading cause of admission, short-term and long-term morbidity, and mortality in this patient group.1,2 Yet, the majority of diagnostic and therapeutic practices in this setting are not based on high-grade evidence. This exposes children to…
Categories: Latest Headlines, PediatricsTweet
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Mashup Score: 9
These results suggest that cardiac remodelling in children with chronic kidney disease is related to blood pressure control and that a target office systolic blood pressure at the 50th percentile is close to the optimal target for preventing increased left ventricular mass.
Categories: Latest Headlines, NephrologyTweet
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Mashup Score: 3Real-time continuous glucose monitoring in preterm infants (REACT): an international, open-label, randomised controlled trial - 1 year(s) ago
Real-time CGM can reduce exposure to prolonged or severe hyperglycaemia and hypoglycaemia. Further studies using CGM are required to determine optimal glucose targets, strategies to obtain them, and the potential effect on long-term health outcomes.
Categories: Latest Headlines, PediatricsTweet
Metabolic and bariatric surgery versus intensive non-surgical treatment for adolescents with severe obesity (AMOS2): a multicentre, randomised, controlled trial in Sweden - The Lancet Child & Adolescent Health #obesity #bariatricsurgery @ASMBS https://t.co/ZhDZFJLHEn