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Mashup Score: 1Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas. | Read by QxMD - 3 month(s) ago
Despite recent advances in frontline therapy for diffuse large B-cell lymphoma (DLBCL), at least a third of those diagnosed still will require second or further lines for relapsed or refractory (rel/ref) disease. A small minority of these can be cured with standard chemoimmunotherapy/stem-cell transplant salvage approaches. CD19-directed chimeric antigen receptor T-cell (CAR-19) therapies are increasingly altering the prognostic landscape for rel/ref patients with DLBCL and related aggressive B-cell
Source: read.qxmd.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 75Management of Incidentally Detected Gallbladder Polyps: Society of Radiologists in Ultrasound Consensus Conference Recommendations. | Read by QxMD - 5 month(s) ago
Aya Kamaya, Christopher Fung, Jean-Luc Szpakowski, David T Fetzer, Andrew J Walsh, Yewande Alimi, David B Bingham, Michael T Corwin, Nirvikar Dahiya, Helena Gabriel, Walter G Park, Matthew R Porembka, Shuchi K Rodgers, Mitchell E Tublin, Xin Yuan, Yang Zhang, William D Middleton Radiology 2022 November Gallbladder polyps (also known as polypoid lesions of the gallbladder) are a common incidental finding. The vast majority of gallbladder polyps smaller than 10 mm are not true neoplastic polyps but are
Source: read.qxmd.comCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 0
Linda P T Joosten, Sander van Doorn, Peter M van de Ven, Bart T G Köhlen, Melchior C Nierman, Huiberdina L Koek, Martin E W Hemels, Menno V Huisman, Marieke Kruip, Laura M Faber, Nynke M Wiersma, Wim F Buding, Rob Fijnheer, Henk J Adriaansen, Kit C Roes, Arno W Hoes, Frans H Rutten, Geert-Jan Geersing Circulation 2023 August 28 Background: There is ambiguity whether frail patients with atrial fibrillation (AF) managed with vitamin K antagonists (VKAs) should be switched to a non-vitamin K oral anticoagulant
Source: read.qxmd.comCategories: Cardiologists1, Latest HeadlinesTweet-
Take a look at this paper from Read by QxMD: Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial: No Switch https://t.co/KdXX96RVQa https://t.co/nhfciqmyvw
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Mashup Score: 24
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in the United States and worldwide. The progressive form of NAFLD, nonalcoholic steatohepatitis (NASH), is a leading indication for liver transplant. Comorbidities associated with NAFLD development and NASH include type 2 diabetes, obesity, metabolic syndrome, and dyslipidemia. Extrahepatic…
Source: read.qxmd.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Optimizing MATRix as remission induction in PCNSL: de-escalated induction treatment in newly diagnosed primary CNS lymphoma. - 2 year(s) ago
BACKGROUND: Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (PCNSL) is a rare disorder with an increasing incidence over the past decades. High-level evidence has been reported for the MATRix regimen (high-dose methotrexate (HD-MTX), high-dose AraC (HD-AraC), thiotepa and rituximab) followed by high-dose chemotherapy and autologous stem cell transplantation (HCT-ASCT)…
Source: read.qxmd.comCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 31
This review discusses the effects and mechanisms of ketogenic diet on neurodegenerative diseases on the basis of available evidence. A ketogenic diet refers to a high-fat, medium-protein, and low-carbohydrate diet that leads to a metabolic shift to ketosis. This review systematically summarizes the scientific literature supporting this effective treatment approach for neurodegenerative diseases,…
Source: read.qxmd.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 22
This review discusses the effects and mechanisms of ketogenic diet on neurodegenerative diseases on the basis of available evidence. A ketogenic diet refers to a high-fat, medium-protein, and low-carbohydrate diet that leads to a metabolic shift to ketosis. This review systematically summarizes the scientific literature supporting this effective treatment approach for neurodegenerative diseases,…
Source: read.qxmd.comCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0
OBJECTIVE: To assess the quantity and impact of research publications among US acute care hospitals; to identify hospital characteristics associated with publication volumes; and to estimate the independent association of bibliometric indicators with Hospital Compare quality measures. DATA SOURCES: Hospital Compare; American Hospital Association Survey; Magnet Recognition Program; Science…
Source: read.qxmd.comCategories: Emergency Medicine, Latest HeadlinesTweet
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Mashup Score: 0
AIMS: Increases to radiotherapy dose are constrained by normal tissue effects. The relationship between bowel dose volume data and late bowel toxicity in patients with muscle-invasive bladder cancer treated with radical radiotherapy was assessed. MATERIALS AND METHODS: The bowel was contoured retrospectively on radiotherapy plans of 47 patients recruited to the BC2001 trial (CRUK/01/004). The…
Source: read.qxmd.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Must Read Oncology Preprints (shared collection) - 2 year(s) ago
Read papers from the shared collection Must Read Oncology Preprints with Read by QxMD.
Source: read.qxmd.comCategories: Healthcare Professionals, Latest HeadlinesTweet
Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas. https://t.co/z9dDrDv3Gs #lymsm #DLBCL