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Mashup Score: 1Systematic review of adjuvant external beam radiotherapy for hepatocellular carcinoma following radical hepatectomy - 2 year(s) ago
Hepatectomy is still the most cost-effective curative treatment for hepatocellular carcinoma (HCC), but local recurrence remains the dominant pattern of treatment failures, with 5-year recurrence rate as high as 70% [1–3]. In addition, with the improvement of perioperative management, promotion of neoadjuvant treatment, and rise of conversion therapy, an increasing number of patients with lesions…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 6First-in-Human Technique Translation of Oxygen-Enhanced MRI to an MR Linac System in Patients with Head and Neck Cancer - 2 year(s) ago
Tumours contain hypoxic regions, resulting from an imbalance between oxygen supply and consumption (1). Hypoxia is prognostic in head and neck cancer (HNC), being associated with both poor loco-regional control and reduced survival [2–3]. In addition, hypoxia impedes radiation treatment by hindering production of free radicals for tumour DNA damage. Consequently, greater radiation dose is…
Source: Radiotherapy and OncologyCategories: Latest Headlines, Oncologists2Tweet-
First-in-Human technique of the translation of oxygen-enhanced MRI to an #MRlinac system inpPatients with head and neck cancer. Fantastic work by @RT_physics and all the team at the @TheChristieNHS https://t.co/z82T6gvZ3d https://t.co/EBPotGWsHo
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Mashup Score: 0
Multiple studies have shown that over the long-term, 25 to 40 percent of patients treated with a radical prostatectomy experience a biochemical recurrence [1–4]. When this occurs, patients are commonly treated with salvage radiation therapy to the prostate bed. Given that there has been growing evidence supporting the use of prostate stereotactic body radiotherapy (SBRT) in patients with…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet-
https://t.co/hlutuHeD12 https://t.co/uTssUufD8L
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Mashup Score: 0First-in-Human Technique Translation of Oxygen-Enhanced MRI to an MR Linac System in Patients with Head and Neck Cancer - 2 year(s) ago
Tumours contain hypoxic regions, resulting from an imbalance between oxygen supply and consumption (1). Hypoxia is prognostic in head and neck cancer (HNC), being associated with both poor loco-regional control and reduced survival [2–3]. In addition, hypoxia impedes radiation treatment by hindering production of free radicals for tumour DNA damage. Consequently, greater radiation dose is…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet-
First-in-Human Technique Translation of Oxygen-Enhanced MRI to an MR Linac System in Patients with Head and Neck Cancer https://t.co/cCdJcHkdPD
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Mashup Score: 4Same-day adaptive palliative radiotherapy without prior CT simulation: Early outcomes in the FAST-METS study - 2 year(s) ago
Palliative care comprises 30-50% of all radiotherapy (RT) treatments, which is an effective treatment for pain with minimal side effects [1–6] and occasionally improves survival rates [5,7]. However, treatment delays adversely impact quality of life (QoL) and survival of these patients [8]. Fast workflows which reduce delays are available, with a one-stop-shop (OSS) workflow at our department…
Source: Radiotherapy and OncologyCategories: Latest Headlines, Oncologists2Tweet-
Same-day adaptive palliative RT without prior CT simulation: Early outcomes in the FAST-METS study 👉 Great work showing innovative ways how high-tech can generate added benefit for our palliative pts Congrats to Wilko and the Amsterdam team ! https://t.co/nALOAarXLD
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Mashup Score: 2Single vs multiple fraction palliative radiation therapy for bone metastases: Cumulative meta-analysis - 2 year(s) ago
Pain originating from uncomplicated bone metastases, defined as those which have not resulted in and are not at imminent risk for pathological fracture or spinal cord compression, is effectively palliated by conventional external beam radiation therapy (RT) [1,2]. There has been a long-standing debate regarding the efficacy of single fraction (SFRT) compared to multiple fraction RT (MFRT); many…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet-
📣 Meta-analysis of 29 trials of single fraction radiotherapy vs mult fraction for bone mets finds no diff in efficacy. (Single treatment is faster & costs less, so 🏆 for pts). Authors make this plain & say to quit funding these studies! 👏 #OncTwitter https://t.co/bQ0Djj9kCL https://t.co/UVO1roDojs
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Mashup Score: 0
Radiation therapy (RT) combined with hormonal therapy is a standard treatment for intermediate- and high-risk prostate cancers [1,2,3]. Three randomized trials have evaluated the role of prostate brachytherapy boost, and one of several external beam radiation boost studies recently examined the benefits of intraprostatic focal boost [4,5,6,7]. They have shown that dose escalation (DE) improves…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet-
Outcomes following high dose rate #brachytherapy boost for high/intermediate risk #ProstateCancer. Our report shows high efficacy (85% bPFS at 5 years in high risk patients) with low toxicity (HDR better than seeds?). In press @RadiotherapyOn1 https://t.co/Z8J7ZjJYcC https://t.co/tDfCNtlo3p
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Mashup Score: 8First experimental demonstration of VMAT combined with MLC tracking for single and multi fraction lung SBRT on an MR-linac - 2 year(s) ago
A viable alternative for surgery to treat early stage non-small-cell lung cancer is stereotactic body radiation therapy (SBRT) [1,2]. The dose distributions need to be highly conformal around the target to ensure coverage, while sparing adjacent organs at risk (OARs) [3]. Although Intensity Modulated Radiation Therapy (IMRT) produces conformal dose distributions, Volumetric Modulated Arc Therapy…
Source: Radiotherapy and OncologyCategories: Hem/Oncs, Latest HeadlinesTweet-
For those who can understand this, it is a big deal. VMAT can now be combined with MLC tracking on an MR-Linac. Currently not available for clinical use with either MRIdian or UNITY. Thanks @joostverhoeff for sharing. #radonc https://t.co/9zbvhIvSaa https://t.co/TlZorp0vqC
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Mashup Score: 0Assessing the Role of Radiotherapy in Patients with Refractory or Relapsed High-Grade B-Cell Lymphomas Treated with CAR T-Cell Therapy - 2 year(s) ago
Non-Hodgkin lymphoma (NHL) is the most prevalent hematologic malignancy1, accounting for approximately 4.3% of all new cancers and 3.4% of all cancer deaths in the United States2. Diffuse large B-cell lymphoma (DLBCL) constitutes 30-40% of all NHL cases in the U.S.3. In the last few decades, the survival rates have improved to a 5-year relative survival rate of 63.9% in the United States and…
Source: Radiotherapy and OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Assessing the Role of Radiotherapy in Patients with Refractory or Relapsed High-Grade B-Cell Lymphomas Treated with CAR T-Cell Therapy https://t.co/Dv7DdrWA2X #CART #bmtsm #CARTcell #immunotherapy #tcellrx #ICAN #CRS #CARTcells #CellTherapy #Gene #Genetherapy @ASTCT #radiation
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Mashup Score: 1Effect of radiotherapy interruption due to COVID-19 outbreak - 2 year(s) ago
The impact of the COVID-19 pandemic on cancer death was reported recently [1]. Wuhan where COVID-19 broke out has been critically hit [2,3]. The emergence has affected every aspect of health care, including the delivery of standard radiotherapy to patients with cancer. Those patients was facing disruption because of concerns about their susceptibility to the serious risks of COVID-19, travel…
Source: Radiotherapy and OncologyCategories: Latest Headlines, Oncologists2Tweet-
Plus a report from perhaps the world's most covid disrupted #radonc service - the 45 day shutdown of Wuhan's radiotherapy department https://t.co/LHCH52buGf
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@ShaalanBeg @rachnatshroff @TimothyJBrownMD @drlauragoff @NVijayvergiaMD @pashtoonkasi @DavendraSohal @FlavioRochaMD @SyedAAhmad5 Nice, but want to see full paper - patterns of recurrence, OS (and crossover). Also...might there be another modality that could also reduce post-op recurrence? https://t.co/vAKY3ldCGs