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Mashup Score: 1
Artificial intelligence (AI)–synthesized text, audio, image, and video are being weaponized for the purposes of nonconsensual intimate imagery, financial fraud, and disinformation campaigns. Our evaluation of the photorealism of AI-synthesized faces indicates that synthesis engines have passed through the uncanny valley and are capable of creating faces that are indistinguishable—and more…
Source: PNASCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2Radiotherapy transiently reduces the sensitivity of cancer cells to lymphocyte cytotoxicity - 2 year(s) ago
Radiotherapy is one of the most common forms of cancer treatment used today. Its impact in directly killing cancer cells, and on antitumour immunity, is well recognized, but its effect on immune cell–cancer cell interactions is not fully understood. Here, we show that irradiation of cancer cells surprisingly leads to resistance against immune cell cytotoxicity. This was mediated by a reduced…
Source: PNASCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 4An evidence review of face masks against COVID-19 - 2 year(s) ago
The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological considerations, and implementation considerations….
Source: PNASCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis - 2 year(s) ago
Ki-67 is a nuclear protein present in all proliferating vertebrate cells and is widely used as a marker in clinical cancer histopathology. However, its cellular functions have remained largely mysterious, and whether it plays any roles in cancer was unknown. In this work, we show genetically that Ki-67 is not required for cell proliferation in tumors, but it is required for all stages of…
Source: PNASCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Carcinomas assemble a filamentous CXCL12–keratin-19 coating that suppresses T cell–mediated immune attack - 2 year(s) ago
Carcinomas resist immunotherapy because T cells are absent from nests of cancer cells. The chemokine/chemokine receptor system, which regulates the migration of immune cells, is a candidate for this impaired intratumoral accumulation of T cells. Cancer cells in human pancreatic, colorectal, and breast cancers are coated with the chemokine CXCL12 in the form of covalent heterodimers with…
Source: PNASCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 6Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer - 2 year(s) ago
The results provide strong evidence of extensive SARS-CoV-2 infection of white-tailed deer, a free-living wild animal species with widespread distribution across North, Central, and South America. The analysis shows infection of deer resulted from multiple spillovers from humans, followed by efficient deer-to-deer transmission. The discovery of widespread infection of white-tailed deer indicates…
Source: PNASCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 1
What changes in the brain when we lose consciousness? One possibility is that the loss of consciousness corresponds to a transition of the brain’s electric activity away from edge-of-chaos criticality, or the knife’s edge in between stability and chaos. Recent mathematical developments have produced tools for testing this hypothesis, which we apply to cortical recordings from diverse brain…
Source: PNASCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 28
Wearing face masks and maintaining social distance are familiar to many people around the world during the ongoing SARS-CoV-2 pandemic. Evidence suggests that these are effective ways to reduce the risk of SARS-CoV-2 infection. However, it is not clear how exactly the risk of infection is affected by wearing a mask during close personal encounters or by social distancing without a mask. Our…
Source: PNASCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 5
Artificial intelligence (AI)–synthesized text, audio, image, and video are being weaponized for the purposes of nonconsensual intimate imagery, financial fraud, and disinformation campaigns. Our evaluation of the photorealism of AI-synthesized faces indicates that synthesis engines have passed through the uncanny valley and are capable of creating faces that are indistinguishable—and more…
Source: PNASCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 72
Artificial intelligence (AI)–synthesized text, audio, image, and video are being weaponized for the purposes of nonconsensual intimate imagery, financial fraud, and disinformation campaigns. Our evaluation of the photorealism of AI-synthesized faces indicates that synthesis engines have passed through the uncanny valley and are capable of creating faces that are indistinguishable—and more…
Source: PNASCategories: Expert Picks, Latest HeadlinesTweet
AI-synthesized faces are indistinguishable from real faces and more trustworthy | PNAS https://t.co/oW8RrZCgUU