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Mashup Score: 5Explaining paranoia: cognitive and social processes in the occurrence of extreme mistrust - 9 day(s) ago
Background Paranoia—incorrectly thinking that others are deliberating trying to harm you—causes distress, undermines social interactions and leads to withdrawal. It presents across multiple psychiatric diagnoses. Objective The primary aim was to determine the extent that cognitive and social processes may explain paranoia. The secondary aim was to identify explanatory factors that distinguished paranoia and social anxiety. Methods 10 382 UK adults, quota sampled to match the population for age, gender, ethnicity, income and region, participated in a non-probability survey. All participants completed a paranoia measure and assessments of cognitive and social processes. Structural equation modelling was conducted. Findings 2586 (24.9%) participants described being mistrustful of other people. 1756 (16.9%) participants wanted help to trust more. 66.7% of variance in paranoia was explained by a model comprising (in descending order of importance): within-situation defence behaviours, negat
Source: mentalhealth.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 12Relationship between severe mental illness and physical multimorbidity: a meta-analysis and call for action - 9 day(s) ago
Background People with severe mental illness (SMI) have a higher prevalence of several chronic physical health conditions, and the prevalence of physical multimorbidity is expected to rise. The aim of this study was to assess the strength of the association between SMI and physical multimorbidity. Study selection and analysis We systematically searched PubMed/Medline, Scopus, Embase, Web of Science, PsycINFO and the behavioural sciences collection databases, from inception to 31 January 2023, for studies that investigated the association between SMI and physical multimorbidity. Humans of any age either clinically diagnosed and/or currently receiving treatment for SMI, specified as schizophrenia (and related psychotic disorders), bipolar disorder and psychotic depression, were eligible. Data from studies selected for inclusion were converted into ORs, with a subsequent meta-analysis conducted. Findings We included 19 studies with a total of 194 123 patients with SMI with different diagn
Source: mentalhealth.bmj.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0Topic Collection | BMJ Mental Health - 16 day(s) ago
In recent years, there has been a resurgence of interest exploring the intersection sleep/circadian science and mental health. BMJ Mental Health is calling for submissions on circadian mental health research and innovation with particular focus on major depression, psychosis, bipolar disorder, dementia, neurodevelopmental disorders (ASD and ADHD) and substance misuse disorders. Submissions Open | Submission Deadline : 9th June 2024 We are pleased to offer a 25% discount on the Article Processing Charge
Source: mentalhealth.bmj.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0
Background Blurred work–non-work boundaries can have negative effects on mental health, including sleep. Objectives In a randomised control trial, we aimed to assess the effectiveness of an online recovery training programme designed to improve symptoms of insomnia in a working population exposed to blurred boundaries. Methods 128 participants with severe insomnia symptoms (Insomnia Severity Index ≥15) and working under blurred work and non-work conditions (segmentation supplies <2.25) were randomly assigned to either the recovery intervention or a waitlist control group (WLC). The primary outcome was insomnia severity, assessed at baseline, after 2 months (T2) and 6 months (T3). Findings A greater reduction in insomnia was observed in the intervention compared with the WLC group at both T2 ( d =1.51; 95% CI=1.12 o 1.91) and T3 ( d =1.63; 95% CI=1.23 to 2.03]. This was shown by Bayesian analysis of covariance (ANCOVA), whereby the ANCOVA model yielded the highest Bayes factor ( BF 10=3
Source: mentalhealth.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0Topic Collection | BMJ Mental Health - 2 month(s) ago
In recent years, there has been a resurgence of interest exploring the intersection sleep/circadian science and mental health. BMJ Mental Health is calling for submissions on circadian mental health research and innovation with particular focus on major depression, psychosis, bipolar disorder, dementia, neurodevelopmental disorders (ASD and ADHD) and substance misuse disorders. Submissions Open | Submission Deadline : 9th June 2024 We are pleased to offer a 25% discount on the Article Processing Charge
Source: mentalhealth.bmj.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 1Suicide risk assessment tools and prediction models: new evidence, methodological innovations, outdated criticisms - 2 month(s) ago
The number of prediction models for suicide-related outcomes has grown substantially in recent years. These models aim to assist in stratifying risk, improve clinical decision-making, and facilitate a personalised medicine approach to the prevention of suicidal behaviour. However, there are contrasting views as to whether prediction models have potential to inform and improve assessment of suicide risk. In this perspective, we discuss common misconceptions that characterise criticisms of suicide risk prediction research. First, we discuss the limitations of a classification approach to risk assessment (eg, categorising individuals as low-risk vs high-risk), and highlight the benefits of probability estimation. Second, we argue that the preoccupation with classification measures (such as positive predictive value) when assessing a model’s predictive performance is inappropriate, and discuss the importance of clinical context in determining the most appropriate risk threshold for a given
Source: mentalhealth.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0
Question Tricyclic antidepressants are used to treat depression worldwide, but the adverse effects have not been systematically assessed. Our objective was to assess the beneficial and harmful effects of all tricyclic antidepressants for adults with major depressive disorder. Study selection and analysis We conducted a systematic review with meta-analysis and trial sequential analysis. We searched CENTRAL, MEDLINE, Embase, LILACS and other sources from inception to January 2023 for randomised clinical trials comparing tricyclic antidepressants versus placebo or ‘active placebo’ for adults with major depressive disorder. The primary outcomes were depressive symptoms measured on the 17-item Hamilton Depression Rating Scale (HDRS-17), serious adverse events and quality of life. The minimal important difference was defined as three points on the HDRS-17. Findings We included 103 trials randomising 10 590 participants. All results were at high risk of bias, and the certainty of the evidence
Source: mentalhealth.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 2Estimating the smallest worthwhile difference of antidepressants: a cross-sectional survey - 5 month(s) ago
Background Approximately 30% of patients experience substantial improvement in depression after 2 months without treatment, and 45% with antidepressants. The smallest worthwhile difference (SWD) refers to an intervention’s smallest beneficial effect over a comparison patients deem worthwhile given treatment burdens (harms, expenses and inconveniences), but is undetermined for antidepressants. Objective Estimating the SWD of commonly prescribed antidepressants for depression compared to no treatment. Methods The SWD was estimated as a patient-required difference in response rates between antidepressants and no treatment after 2 months. An online cross-sectional survey using Prolific, MQ Mental Health and Amazon Mechanical Turk crowdsourcing services in the UK and USA between October 2022 and January 2023 garnered participants (N=935) that were a mean age of 44.1 (SD=13.9) and 66% women (n=617). Findings Of 935 participants, 124 reported moderate-to-severe depressive symptoms but were no
Source: mentalhealth.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0Topic Collection | BMJ Mental Health - 6 month(s) ago
In recent years, there has been a resurgence of interest exploring the intersection sleep/circadian science and mental health. BMJ Mental Health is calling for submissions on circadian mental health research and innovation with particular focus on major depression, psychosis, bipolar disorder, dementia, neurodevelopmental disorders (ASD and ADHD) and substance misuse disorders. Submissions Open | Submission Deadline : 9th June 2024 We are pleased to offer a 25% discount on the Article Processing Charge
Source: mentalhealth.bmj.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0Topic Collection | BMJ Mental Health - 7 month(s) ago
In recent years, there has been a resurgence of interest exploring the intersection sleep/circadian science and mental health. BMJ Mental Health is calling for submissions on circadian mental health research and innovation with particular focus on major depression, psychosis, bipolar disorder, dementia, neurodevelopmental disorders (ASD and ADHD) and substance misuse disorders. Submissions Open | Submission Deadline : 9th June 2024 We are pleased to offer a 25% discount on the Article Processing Charge
Source: mentalhealth.bmj.comCategories: General Medicine News, General Journals & SocietTweet
Explaining paranoia: cognitive and social processes in the occurrence of extreme mistrust https://t.co/TICQMjySOf via @ProfDFreeman et al https://t.co/lWQhajWZ9v