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Mashup Score: 92Cardiorenal Disease and Heart Failure with Preserved Ejection Fraction: Two Sides of the Same Coin - 1 month(s) ago
Abstract. Background: Heart failure with preserved ejection fraction (HFpEF) and chronic kidney disease (CKD) have a strong pathophysiological interrelationship, and their combination worsens prognosis. Summary: This article briefly reviews the bidirectional epidemiological burden and the pathophysiological interplay between HFpEF and CKD. It also discusses some of the controversial aspects regarding the diagnosis and screening of HFpEF in CKD patients and focuses on the most effective therapeutic approaches to improve symptoms and prognosis in this high-risk population. Key Messages: Due to its prevalence and prognostic significance, HFpEF screening should be considered in patients with CKD, with careful use of traditional diagnostic tools in this population. Optimal medical therapy has seen major recent advances in patients with both HFpEF and CKD. SGLT2 inhibitors, finerenone, and semaglutide have consistently demonstrated cardio- and renoprotective effects in both conditions.
Source: karger.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0Prospective Evaluation of Remote Software Based Surveillance Supplementing Clinical Monitoring For Hemodialysis Vascular Access - 1 month(s) ago
Abstract. Background and Hypothesis: Efficient arteriovenous access (VA) surveillance is vital for early identification of dysfunctional access, allowing timely intervention to prevent thrombosis. This study compares the efficacy of adding remote software surveillance to standard clinical care across our units. Methods: We conducted a 12-month prospective study on maintenance hemodialysis (HD) patients using Vasc-Alert software technology to assist clinical decision-making in 2 satellite HD units (Group 1) and standard care in the remaining 3 HD units (Group 2) . Patients with Vasc-alert derived high Access Risk Score (ARS) (≥7) underwent clinical assessment and were referred for fistulogram based on relevant Kidney Disease Outcome Quality Initiative (KDOQI) criteria. Data on referrals for fistulogram, subsequent VA events, access abandonment, and complication-free days- extended (CFD-extended) were collected.. VA survival analysis of post-intervention primary patency rate at 3 and 6 m
Source: karger.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 33
Abstract. Background: Cardiovascular and infective complications are commonly observed in patients receiving hemodialysis (HD) with cardiovascular events and infection-related complications being the first and second leading causes of death. Infective endocarditis (IE) is characterized by inflammation of the endocardium caused by infection, typically affecting the cardiac valves and can be in acute, subacute, or chronic forms. It is a serious complication within the HD population due to their predisposition for both infection and valvular damage. Considering the frailty and burden of comorbidities in those receiving HD, management of IE in the HD population is very challenging. There has been continuous discussion and debate on optimizing the diagnostic and treatment approach of IE in this patient group to improve their clinical outcomes. Currently, reported outcomes are relatively poor and there are updates from numerous guidelines relating to advances in IE management. Summary: In th
Source: karger.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 10
Abstract. Regular physical activity and exercise (PA) are cornerstones of diabetes care for individuals with type 1 diabetes. In recent years, the availability of automated insulin delivery (AID) systems has improved the ability of people with type 1 diabetes to achieve the recommended glucose target ranges. PA provides additional health benefits but can cause glucose fluctuations, which challenges current AID systems. While an increasing number of clinical trials and reviews are being published on different AID systems and PA, it seems prudent at this time to collate this information and develop a position statement on the topic. This joint European Association for the Study of Diabetes (EASD)/International Society for Pediatric and Adolescent Diabetes (ISPAD) position statement reviews current evidence on AID systems and provides detailed clinical practice points for managing PA in children, adolescents and adults with type 1 diabetes using AID technology. It discusses each commercia
Source: karger.comCategories: General Medicine News, PediatricsTweet
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Mashup Score: 31
Abstract. Background: Cardiovascular and infective complications are commonly observed in patients receiving hemodialysis (HD) with cardiovascular events and infection-related complications being the first and second leading causes of death. Infective endocarditis (IE) is characterized by inflammation of the endocardium caused by infection, typically affecting the cardiac valves and can be in acute, subacute, or chronic forms. It is a serious complication within the HD population due to their predisposition for both infection and valvular damage. Considering the frailty and burden of comorbidities in those receiving HD, management of IE in the HD population is very challenging. There has been continuous discussion and debate on optimizing the diagnostic and treatment approach of IE in this patient group to improve their clinical outcomes. Currently, reported outcomes are relatively poor and there are updates from numerous guidelines relating to advances in IE management. Summary: In th
Source: karger.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 8
Mohammad Salman Sheikh, Charat Thong prayoon, Supawadee Suppadungsuk, Jing Miao, Fawad Qureshi, Kianoush Kashani, Wisit Cheungpasitporn; The Future of AI-Assisted Patient Education in Critical Care Nephrology . Blood Purif 2024; https://doi.org/10.1159/000543350 This content is only available via PDF. You do not currently have access to this content. Don’ t already have an account? Register This article is also available for rental through DeepDyve.
Source: karger.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 10
Abstract. Regular physical activity and exercise (PA) are cornerstones of diabetes care for individuals with type 1 diabetes. In recent years, the availability of automated insulin delivery (AID) systems has improved the ability of people with type 1 diabetes to achieve the recommended glucose target ranges. PA provides additional health benefits but can cause glucose fluctuations, which challenges current AID systems. While an increasing number of clinical trials and reviews are being published on different AID systems and PA, it seems prudent at this time to collate this information and develop a position statement on the topic. This joint European Association for the Study of Diabetes (EASD)/International Society for Pediatric and Adolescent Diabetes (ISPAD) position statement reviews current evidence on AID systems and provides detailed clinical practice points for managing PA in children, adolescents and adults with type 1 diabetes using AID technology. It discusses each commercia
Source: karger.comCategories: General Medicine News, PediatricsTweet
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Mashup Score: 0SickKids Handbook of Pediatric Thrombosis and Hemostasis: 3rd, revised and extended edition - 3 month(s) ago
This Handbook takes the reader through the entire field of pediatric thrombosis and hemostasis and has been updated since the 2nd edition with considerable
Source: karger.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 23ANCA-associated glomerulonephritis – diagnosis and therapy Proceedings of the Henry Shavelle Lectureship - 3 month(s) ago
Abstract. Background. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) frequently affects the kidney. Glomerulonephritis (GN) in AAV, ANCA-GN, not only dictates therapeutic decisions, but is also of relevance for overall survival influencing the risk of cardiovascular disease and serious infections. Summary. A diagnosis of ANCA-GN includes laboratory investigations including urinalysis and a thorough assessment of potential organ involvement. A kidney biopsy can be performed to ascertain the diagnosis, but has an additional prognostic relevance and tools have been established to predict long-term kidney survival. Experimental biomarkers indicating kidney inflammation include urinary soluble CD163 and the presence of urinary T cells. Therapeutic options are refined and some of these therapies, such as the added value of performing plasma exchange, are the matter of controversial discussions. Safe reduction of cumulative exposure to glucocorticoids and eventually t
Source: karger.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 9ISPAD Position Statement on Type 1 Diabetes in Schools - 4 month(s) ago
The International Society for Pediatric and Adolescent Diabetes (ISPAD) strongly supports compliance with legal protections for children and adolescents with type 1 diabetes (T1D) to attend school, to be safe at school, and to receive optimal medical management during all school-associated activities [1]. ISPAD’s Clinical Practice Consensus Guidelines [2‒7] provide clinicians with concepts and standards for best clinical practice. To implement best clinical practice while the student is in the custody of the school requires understanding, respect, and compliance with the relevant legal frameworks [1‒3]. The task is to execute medically complex management in a workplace designed for education. In recognition of the unique workplace requirements, ISPAD first commissioned the ISPAD Position Statement on Type 1 Diabetes in Schools in 2018 [1] to assist schools to implement the Clinical Practice Consensus Guidelines’ concepts [2]. This 2024 Position Statement aims to clearly inform educatio
Source: karger.comCategories: General Medicine News, PediatricsTweet
Cardiorenal Disease and Heart Failure with Preserved Ejection Fraction: Two Sides of the Same Coin Ya disponible nuestra revisión con @gonnumar en #cardiorenalMed 👉 https://t.co/lZduUMxUgL https://t.co/b3wW0zvoHI