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Mashup Score: 2Cardiorenal Disease and Heart Failure with Preserved Ejection Fraction: Two Sides of the Same Coin - 5 hour(s) ago
Abstract. Background: Heart failure with preserved ejection fraction (HFpEF) and chronic kidney disease (CKD) have a strong pathophysiological interrelationship, and their combination worsens prognosis. Summary: This article briefly reviews the bidirectional epidemiological burden and the pathophysiological interplay between HFpEF and CKD. It also discusses some of the controversial aspects regarding the diagnosis and screening of HFpEF in CKD patients and focuses on the most effective therapeutic approaches to improve symptoms and prognosis in this high-risk population. Key Messages: Due to its prevalence and prognostic significance, HFpEF screening should be considered in patients with CKD, with careful use of traditional diagnostic tools in this population. Optimal medical therapy has seen major recent advances in patients with both HFpEF and CKD. SGLT2 inhibitors, finerenone, and semaglutide have consistently demonstrated cardio- and renoprotective effects in both conditions.
Source: karger.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 67
Abstract. There should be no assumption that an athlete is immune to coronary artery disease (CAD), even when traditional cardiovascular (CV) risk factors
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 13Start your day with a morning coffee! - 1 month(s) ago
This editorial refers to ‘Coffee drinking timing and mortality in US adults’, by X. Wang et al., https://doi.org/10.1093/eurheartj/ehae871.
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 35Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease - 3 month(s) ago
AbstractBackground and Aims. Individuals with heart failure (HF), other forms of cardiovascular disease, or kidney disease are at increased risk for the de
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 14Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy - 3 month(s) ago
AbstractBackgroundObesity is a known risk factor for heart failure with preserved ejection fraction (HFpEF) and is considered a distinct phenotype with more concentric remodeling. Epicardial adipos…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0Contemporary Use and Implications of Beta-Blockers in Patients With HFmrEF or HFpEF: The DELIVER Trial - 5 month(s) ago
Abstract Background Although beta-blockers are not recommended for the treatment of heart failure with preserved ejection fraction (HFpEF) according to the latest European Society of Cardiology and…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 46Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-Related Heart Failure: - 6 month(s) ago
AbstractBackgroundObesity is associated with adverse cardiac remodeling and is a key driver for the development and progression of heart failure (HF). Once-weekly semaglutide (2.4 mg) has been show…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 8Evaluation and management of hypertensive emergency - 6 month(s) ago
Hypertensive emergencies cause substantial morbidity and mortality, particularly when acute organ injury is present. Careful and effective strategies to reduce blood pressure and diminish the effects of pressure-mediated injury are essential. While the selection of specific antihypertensive medications varies little across different forms of hypertensive emergencies, the intensity of blood pressure reduction to the target pressure differs substantially. Treatment hinges on balancing the positive effects of lowering blood pressure with the potential for negative effects of organ hypoperfusion in patients with altered autoregulatory mechanisms. When patients do not have acute organ injury in addition to severe hypertension, they benefit from a conservative, outpatient approach to blood pressure management. In all cases, long term control of blood pressure is paramount to prevent recurrent hypertensive emergencies and improve overall prognosis. This review discusses the current evidence a
Source: www.bmj.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 8Evaluation and management of hypertensive emergency - 6 month(s) ago
Hypertensive emergencies cause substantial morbidity and mortality, particularly when acute organ injury is present. Careful and effective strategies to reduce blood pressure and diminish the effects of pressure-mediated injury are essential. While the selection of specific antihypertensive medications varies little across different forms of hypertensive emergencies, the intensity of blood pressure reduction to the target pressure differs substantially. Treatment hinges on balancing the positive effects of lowering blood pressure with the potential for negative effects of organ hypoperfusion in patients with altered autoregulatory mechanisms. When patients do not have acute organ injury in addition to severe hypertension, they benefit from a conservative, outpatient approach to blood pressure management. In all cases, long term control of blood pressure is paramount to prevent recurrent hypertensive emergencies and improve overall prognosis. This review discusses the current evidence a
Source: www.bmj.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 7Evaluation and management of hypertensive emergency - 7 month(s) ago
Hypertensive emergencies cause substantial morbidity and mortality, particularly when acute organ injury is present. Careful and effective strategies to reduce blood pressure and diminish the effects of pressure-mediated injury are essential. While the selection of specific antihypertensive medications varies little across different forms of hypertensive emergencies, the intensity of blood pressure reduction to the target pressure differs substantially. Treatment hinges on balancing the positive effects of lowering blood pressure with the potential for negative effects of organ hypoperfusion in patients with altered autoregulatory mechanisms. When patients do not have acute organ injury in addition to severe hypertension, they benefit from a conservative, outpatient approach to blood pressure management. In all cases, long term control of blood pressure is paramount to prevent recurrent hypertensive emergencies and improve overall prognosis. This review discusses the current evidence a
Source: www.bmj.comCategories: General Medicine News, CardiologistsTweet
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