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Mashup Score: 0Lack of Adherence to Guideline-Based Imaging Before Subsequent Radiation in Patients with Non–Small Cell Lung Cancer: Impact on Patient Outcomes - 1 year(s) ago
Lung cancer is the leading cause of cancer death within the United States, yet prior studies have shown a lack of adherence to imaging and treatment guidelines in patients with lung cancer. This study evaluated the use of 18F-FDG PET/CT imaging before subsequent radiation therapy (RT) in patients with non–small cell lung cancer (NSCLC), as recommended by National Comprehensive Cancer Network…
Source: Journal of Nuclear MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Prostate-specific membrane antigen (PSMA) PET offers an accuracy superior to other imaging modalities in initial staging of prostate cancer and is more likely to affect management. We examined the prognostic value of 68Ga-PSMA-11 uptake in the primary lesion and presence of metastatic disease on PET in newly diagnosed prostate cancer patients before initial therapy. Methods: In a prospective…
Source: Journal of Nuclear MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Prevalence and Outcomes of Cardiac Amyloidosis in All-Comer Referrals for Bone Scintigraphy - 1 year(s) ago
The prevalence of cardiac amyloidosis (CA) in the general population and associated prognostic implications remain poorly understood. We aimed to identify CA prevalence and outcomes in bone scintigraphy referrals. Methods: Consecutive all-comers undergoing 99mTc-3,3-diphosphono-1,2-propanodicarboxylic-acid (99mTc-DPD) bone scintigraphy between 2010 and 2020 were included. Perugini grade 1 was…
Source: Journal of Nuclear MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Acetazolamide Stress Brain-Perfusion SPECT Predicts the Need for Carotid Shunting During Carotid Endarterectomy - 2 year(s) ago
Although carotid shunting is occasionally necessary to prevent cerebral ischemia during carotid endarterectomy, there is no reliable indication for this procedure. The purpose of this study was to evaluate whether acetazolamide stress brain-perfusion SPECT can predict the need for carotid shunting during carotid endarterectomy. Methods: Basal and acetazolamide stress brain-perfusion SPECT imaging…
Source: Journal of Nuclear MedicineCategories: Latest Headlines, NeurologyTweet-
How to test reserve? Diamox SPECT or TCD w CO2. Diamox dilates arterioles inc CBV & CBF. If no increase seen, then the arterioles are maximally dilated & this is beyond stage I. CBF can go down in severe hemodynamic failure (reverse robin-hood phenomenon)! https://t.co/tQVcCpToda https://t.co/PNxO0wJPEF
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Mashup Score: 13Imaging of C-X-C Motif Chemokine Receptor 4 Expression in 690 Patients with Solid or Hematologic Neoplasms Using 68Ga-Pentixafor PET - 2 year(s) ago
In recent years, molecular imaging addressing the C-X-C motif chemokine receptor 4 (CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess radiopharmaceutical uptake and image contrast to determine the most relevant clinical applications for CXCR4-directed imaging. We also investigated the impact of specific activity on scan contrast. Methods: Patients ( n = 690)…
Source: Journal of Nuclear MedicineCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2
Background: In addition to its high prognostic value, the involvement of axillary lymph nodes in breast cancer patients also plays an important role in therapy planning. Therefore, an imaging modality that can determine nodal status with high accuracy in primary breast cancer patients is desirable. Purpose: To investigate if machine-learning prediction models based on simple assessable imaging…
Source: Journal of Nuclear MedicineCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 5
Background: In addition to its high prognostic value, the involvement of axillary lymph nodes in breast cancer patients also plays an important role in therapy planning. Therefore, an imaging modality that can determine nodal status with high accuracy in primary breast cancer patients is desirable. Purpose: To investigate if machine-learning prediction models based on simple assessable imaging…
Source: Journal of Nuclear MedicineCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1
Purpose : Indeterminate bone lesions (IBLs) on prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) are common. This study aims to define variables that predict whether such lesions are likely malignant or benign using features on PSMA PET/CT. Methods : 18F-DCFPyL PET/CT imaging was performed in 243 consecutive patients with high-risk primary or…
Source: Journal of Nuclear MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4Assessing Reactive Astrogliosis with 18F-SMBT-1 Across the Alzheimer Disease Spectrum - 2 year(s) ago
A neuroinflammatory reaction in Alzheimer disease (AD) brains involves reactive astrocytes that overexpress monoamine oxidase-B (MAO-B). 18F-( S )-(2-methylpyrid-5-yl)-6-[(3-fluoro-2-hydroxy)propoxy]quinoline (18F-SMBT-1) is a novel 18F PET tracer highly selective for MAO-B. We characterized the clinical performance of 18F-SMBT-1 PET across the AD continuum as a potential surrogate marker of…
Source: Journal of Nuclear MedicineCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
Rationale: To investigate nuclear medicine scientists’ experience with scientific fraud, publication bias, and honorary authorship. Methods: Corresponding authors who published an article in one of the 15 general nuclear medicine journals (according to the Journal Citation Reports) in 2021, received an invitation to participate in a survey on scientific integrity. Results: A total of 254(12.4%)…
Source: Journal of Nuclear MedicineCategories: Cardiologists, Latest HeadlinesTweet
Getting PET/CT vs CT alone prior to #NSCLC RT assoc w/ sockdolager of a survival advantage, ~40% v ~25% at 3y (P<0.001) ~5000 SEER pts ~44% imaged w/ CT alone prior to RT(!) Getting PET most assoc w/ surgery; Getting CT only most assoc w/ chemoRT(!) https://t.co/PRk417DUYt https://t.co/BbyO14LgAG