2 min read When making heatmaps, we always have many additionally grouping information for the samples, sush as subtypes, phenotypes. To emphasize the difference between groups, we might want to only perform clustering on group level, while not on the complete dataset. For these scenarios, ComplexHeatmap has two functions: cluster_between_groups() and cluster_within_group(). The two functions all perform clustering on group level. The difference is, in cluster_between_groups(), inside each group, the