• Mashup Score: 3

    Classification involves a forced-choice premature decision, and is often misused in machine learning applications. Probability modeling involves the quantification of tendencies and usually addresses the real project goals.

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    • RT @f2harrell: @n_grubor Classification is an improper goal in this setting - see https://t.co/LsNcTfyS2l . Sounds like the field has foun…

  • Mashup Score: 14

    Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.

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    • RT @LabWaggoner: ZEB2 is a master switch controlling the tumor-associated macrophage program https://t.co/sw6XERjIzm @Cancer_Cell @IdoAmitL…

  • Mashup Score: 14

    Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.

    Tweet Tweets with this article
    • RT @LabWaggoner: ZEB2 is a master switch controlling the tumor-associated macrophage program https://t.co/sw6XERjIzm @Cancer_Cell @IdoAmitL…

  • Mashup Score: 14

    Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.

    Tweet Tweets with this article
    • RT @LabWaggoner: ZEB2 is a master switch controlling the tumor-associated macrophage program https://t.co/sw6XERjIzm @Cancer_Cell @IdoAmitL…

  • Mashup Score: 14

    Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.

    Tweet Tweets with this article
    • RT @LabWaggoner: ZEB2 is a master switch controlling the tumor-associated macrophage program https://t.co/sw6XERjIzm @Cancer_Cell @IdoAmitL…