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Mashup Score: 3Statistical Thinking - Classification vs. Prediction - 16 hour(s) ago
Classification involves a forced-choice premature decision, and is often misused in machine learning applications. Probability modeling involves the quantification of tendencies and usually addresses the real project goals.
Source: www.fharrell.comCategories: General Medicine NewsTweet
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Mashup Score: 14
Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.
Source: www.cell.comCategories: General Medicine NewsTweet
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Mashup Score: 14
Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.
Source: www.cell.comCategories: General Medicine NewsTweet
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Mashup Score: 14
Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.
Source: www.cell.comCategories: General Medicine NewsTweet
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Mashup Score: 14
Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key driver of the pro-tumor TAM program. Targeting of ZEB2 epigenetically reprograms TAMs, enhances T cell responses, and promotes anti-tumor immunity.
Source: www.cell.comCategories: General Medicine NewsTweet
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Mashup Score: 3HoLISTIC: Hodgkin Lymphoma International Study for Individual Care - 1 month(s) ago
Enhancing evidence-based decision support to optimize care for individual patients.
Source: www.hodgkinconsortium.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 10The dark zone of CNS relapse in DLBCL - 3 month(s) ago
In this issue of Blood, Alduaij and colleagues report on central nervous system (CNS) relapse rates in a retrospective cohort of patients with high-grade B
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 10The dark zone of CNS relapse in DLBCL - 3 month(s) ago
In this issue of Blood, Alduaij and colleagues report on central nervous system (CNS) relapse rates in a retrospective cohort of patients with high-grade B
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 47Frontiers | Natural killer cell engagers for cancer immunotherapy - 3 month(s) ago
1 Department of Pharmaceutics, Rutgers University, Piscataway, NJ, United States 2 Cancer Pharmacology Program, Cancer Institute of New Jersey, New Brunswick, NJ, United States This review article explores the rapidly evolving field of bi-, tri-, and multi-specific NK cell engagers (NKCEs), highlighting their potential as a cutting-edge approach in cancer immunotherapy. NKCEs offer a significant advancement over convent ional monoclonal antibodies (mAbs) by enhancing Antibody-Dependent Cellular Cytotoxicit
Source: www.frontiersin.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 24SEED-Selection enables high-efficiency enrichment of primary T cells edited at multiple loci - 3 month(s) ago
Nature Biotechnology – Primary T cells with multiple genetic modifications are rapidly isolated by negative selection.
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
RT @f2harrell: @n_grubor Classification is an improper goal in this setting - see https://t.co/LsNcTfyS2l . Sounds like the field has foun…