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Mashup Score: 62
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To address how lncRNA loci and their transcripts, structures, interactions, and functions contribute to human traits and disease, we adopt a genome-wide perspective. We intend to provoke alternative interpretation of questionable evidence and thorough inquiry into unsubstantiated claims. We discuss pitfalls of…
Source: Annual ReviewsCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 11
Migration is an essential cellular process that regulates human organ development and homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell migration is strongly associated with immune cell infiltration, immune escape, and tumor cell metastasis, which ultimately account for more than 90% of cancer deaths. The biophysics and molecular regulation of the…
Source: Annual ReviewsCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 6
Migration is an essential cellular process that regulates human organ development and homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell migration is strongly associated with immune cell infiltration, immune escape, and tumor cell metastasis, which ultimately account for more than 90% of cancer deaths. The biophysics and molecular regulation of the…
Source: Annual ReviewsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 15
Migration is an essential cellular process that regulates human organ development and homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell migration is strongly associated with immune cell infiltration, immune escape, and tumor cell metastasis, which ultimately account for more than 90% of cancer deaths. The biophysics and molecular regulation of the…
Source: Annual ReviewsCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 8
Migration is an essential cellular process that regulates human organ development and homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell migration is strongly associated with immune cell infiltration, immune escape, and tumor cell metastasis, which ultimately account for more than 90% of cancer deaths. The biophysics and molecular regulation of the…
Source: Annual ReviewsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe, and highly skilled activities, such as a professional playing a tennis match or a violin concerto, depend upon the ability of the brain to quickly make moment-to-moment adjustments to our behavior in response to the results of our actions. Particularly, they depend upon the ability of the neocortex to…
Source: Annual ReviewsCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 3The Recent Rise of Suicide Mortality in the United States - 2 year(s) ago
Suicide is a major public health concern in the United States. Between 2000 and 2018, US suicide rates increased by 35%, contributing to the stagnation and subsequent decrease in US life expectancy. During 2019, suicide declined modestly, mostly owing to slight reductions in suicides among Whites. Suicide rates, however, continued to increase or remained stable among all other racial/ethnic…
Source: Annual ReviewsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4Mesoaccumbal Dopamine Heterogeneity: What Do Dopamine Firing and Release Have to Do with It? - 2 year(s) ago
Ventral tegmental area (VTA) dopamine (DA) neurons are often thought to uniformly encode reward prediction errors. Conversely, DA release in the nucleus accumbens (NAc), the prominent projection target of these neurons, has been implicated in reinforcement learning, motivation, aversion, and incentive salience. This contrast between heterogeneous functions of DA release versus a homogeneous role…
Source: Annual ReviewsCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 1Machine Learning Methods That Economists Should Know About - 2 year(s) ago
We discuss the relevance of the recent machine learning (ML) literature for economics and econometrics. First we discuss the differences in goals, methods, and settings between the ML literature and the traditional econometrics and statistics literatures. Then we discuss some specific methods from the ML literature that we view as important for empirical researchers in economics. These include…
Source: Annual ReviewsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Seasonality of Respiratory Viral Infections - 2 year(s) ago
The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions. Moreover, epidemics caused by viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and the newly emerging SARS-CoV-2 occur during the…
Source: Annual ReviewsCategories: Infectious Disease, Latest HeadlinesTweet
RT @cshperspectives: Amazing that a field (lncRNAs) is so problematic a review needs a table of logical fallacies https://t.co/yuzGdSEB7b h…