Traveling to different regions, one might encounter a species to which they have a known allergy, or other related and unrelated species. A first-time systemic reaction can occur while on vacation, even in those with previous asymptomatic stings. Three main groups of Hymenoptera are responsible for most sting reactions. Honey bee species are virtually identical around the world. Among social…

: The HDM sublingual immunotherapy (SLIT)-tablet is a treatment option for allergic rhinitis with/without conjunctivitis (AR/C) approved in adults worldwide and in adolescents in some countries.

Home reactions requiring epinephrine administration, a marker of their severity, restrict the widespread use of oral immunotherapy (OIT), but their risk factors are largely not known.

Little is known regarding the prediction of the risks of asthma exacerbation after stopping asthma biologics.

Skin prick testing for the evaluation of allergic disease has greatly evolved from Dr Charles Blackley’s original technique of using a bandage to occlude pollen grains next to the abraded epidermis.1 We now have the widespread use of disposable skin prick devices coated with a liquid allergen or applied through drops of liquid allergen into the epidermis to observe for a wheal and flare…

Food-protein–induced enterocolitis syndrome (FPIES) remains underrecognized owing to its broad differential diagnosis and lack of confirmatory diagnostic tests. Although awareness of pediatric FPIES is slowly increasing in the medical community, awareness of adult FPIES lags, despite 0.22% of US adults reporting FPIES symptoms.1 The differences in presentation and food triggers contribute to the…

Atopic dermatitis (AD) is a common chronic inflammatory skin disease recognized as a global health problem.1,2 The Global Burden of Disease Study showed that dermatitis including AD was the leading skin disease in terms of global burden of disease measured by disability-adjusted life years.3 Recent epidemiologic studies in the United States showed prevalence of up to 18% in school aged children4…

The Joint Task Force for the American Academy of Allergy Asthma Immunology and American College of Allergy Asthma Immunology and the American Gastroenterology Association recently published guidelines for the management of eosinophilic esophagitis (EoE). Because the guideline was published, dupilumab became the first and only medication to gain regulatory approval for the treatment of EoE. This…