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Mashup Score: 1Long sleep duration may be associated with carotid plaque burden | 2 Minute Medicine - 9 month(s) ago
1. In this cross-sectional analysis, long sleep duration (≥9 hours) was significantly associated with carotid plaque presence and larger total plaque area. 2. However, short sleep duration and daytime sleepiness showed no association with carotid plaque burden. Evidence Rating Level: 2 (Good) Sleep is an essential part of cardiovascular health, as the American Heart Association
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Mashup Score: 0
1. Overall survival is longer for patients receiving a combination of lenvatinib plus pembrolizumab as compared with chemotherapy treatment alone 2. Progression-free survival was greater in the group receiving combination therapy Evidence Rating Level: 1 (Excellent) Study Rundown: This study examined whether treatment with the combination of lenvatinib plus pembrolizumab provided greater benefits…
Source: 2 Minute MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
1. In this randomized clinical trial, among 167 older adults with frailty and non-ST segment elevation acute myocardial infarction (NSTEMI), a routine invasive strategy did not significantly increase the number of days alive and out of the hospital from discharge to 1-year when compared to a conservative strategy. 2. Days alive and out of the
Source: 2 Minute MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 1NT-proBNP associated with risk for incident heart failure and all-cause mortality | 2 Minute Medicine - 1 year(s) ago
1. In this prospective cohort study, among 9776 individuals, an NT-proBNP level of 125pg/mL or higher was associated with risk for incident heart failure and mortality. 2. Changes in systolic blood pressure, low-density lipoprotein cholesterol, triglyceride levels, body mass index, and estimated glomerular filtration rate were found to be significantly associated with changes in NT-proBNP.
Source: 2 Minute MedicineCategories: Expert Picks, Latest HeadlinesTweet
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Mashup Score: 0Telehealth treatment is effective in managing behavior problems in children with developmental delay | 2 Minute Medicine - 1 year(s) ago
1. In a randomized clinical trial, internet-delivered parent-child interaction therapy (iPCIT) was associated with improvements in externalizing behaviors, positive parenting skills, and decreased use of harsh and inconsistent discipline. 2. iPCIT therapy has high rates of parental satisfaction post-intervention. Evidence Rating Level: 1 (Excellent) Study Rundown: Behavioral and externalizing…
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Clinical decision-making strategy improves acute heart failure outcomes | 2 Minute Medicine - 1 year(s) ago
1. A hospital-based strategy to support clinical decision-making and rapid follow-up resulted in a lower risk of death and hospitalization in patients with acute heart failure. 2. These outcome improvements were sustained at up to 20 months of follow-up. Evidence Rating Level: 1 (Excellent) Study Rundown: Over 25 million people are affected by heart failure.
Source: 2 Minute MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Balanced intravenous solutions reduce risk of hyperchloremia in the pediatric intensive care unit | 2 Minute Medicine - 1 year(s) ago
1. In a randomized controlled trial of critically ill pediatric patients requiring intravenous fluid therapy, children receiving saline were significantly more likely to have a serum chloride rise of 5 mEq/L than those receiving either gluconate/acetate-buffered solution or lactate-buffered solution. 2. The odds of a serum chloride rise within 48 hours were reduced by 50%
Source: 2 Minute MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Neutrophil CD64 index may be superior for screening for pediatric infections in the ICU | 2 Minute Medicine - 1 year(s) ago
1. In this prospective observational study, infected pediatric intensive care unit (ICU) patients had a significantly higher neutrophil CD 64 (nCD64), C-reactive protein (CRP), and procalcitonin (PCT) than patients without an infection. 2. The nCD64 index was found to have a greater diagnostic value than both CRP and PCT in this study, and the median nCD64
Source: 2 Minute MedicineCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 2Virtual pediatric acute care visits within the medical home are safe and acceptable to parents | 2 Minute Medicine - 1 year(s) ago
1. In a mixed-methods study, pediatric virtual acute care with a provider from the child’s regular medical home was associated with decreased antibiotic prescribing and no changes in unanticipated emergency visits. 2. Parents gave higher experience scores and appreciated the convenience of virtual care, but had concerns with safety, distractibility, and technology-related difficulties. Evidence…
Source: 2 Minute MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 0Low neighborhood opportunities lead to increased disease severity and hospitalizations | 2 Minute Medicine - 1 year(s) ago
1. In a retrospective study, patients with lower neighborhood advantage are hospitalized more frequently, have greater disease severity, and have increased mortality compared to those with higher neighborhood advantage. 2. Diagnoses disproportionally affecting lower neighborhood advantage patients include type 2 diabetes with complications, asthma, and sleep apnea. Evidence Rating Level: 2 (Good)…
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet
Excessively long sleep duration may be associated with carotid plaque burden https://t.co/AFHpu5RcZQ