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Mashup Score: 3Patient-reported outcome measures in cardiovascular disease have limited validation of psychometric properties | 2 Minute Medicine - 2 year(s) ago
1. In 50 patient-reported outcome measures evaluated, only a small minority reported the validation of all Food and Drug Administration (FDA)-recommended psychometric properties. 2. Patient-reported outcome measures (PROMs) rarely had psychometric properties rated as sufficient by consensus-based standards. Evidence Rating Level: 1 (Excellent) Study Rundown: PROs are reported directly by patients…
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Patient-reported outcome measures in cardiovascular disease have limited validation of psychometric properties | 2 Minute Medicine - 2 year(s) ago
1. In 50 patient-reported outcome measures evaluated, only a small minority reported the validation of all Food and Drug Administration (FDA)-recommended psychometric properties. 2. Patient-reported outcome measures (PROMs) rarely had psychometric properties rated as sufficient by consensus-based standards. Evidence Rating Level: 1 (Excellent) Study Rundown: PROs are reported directly by patients…
Source: 2 Minute MedicineCategories: Cardiologists, Latest HeadlinesTweet-
#PROMs in #cardiovascular disease have limited validation of #psychometric properties https://t.co/RZH0NtGycE https://t.co/I2cYKUCBct @derek_c1 @serawhitelaw
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Mashup Score: 1Tofersen does not improve ALS symptoms in patients with SOD1 mutations | 2 Minute Medicine - 2 year(s) ago
1. In patients with amyotrophic lateral sclerosis (ALS) and superoxide dismutase 1 (SOD1) mutations, tofersen does not result in significant functional improvement as compared to placebo. 2. In comparison to the placebo, tofersen significantly reduced SOD1 concentrations in the cerebrospinal fluid (CSF) and plasma of persons with faster progressing SOD1 ALS. Evidence Rating Level: 1
Source: 2 Minute MedicineCategories: Latest Headlines, Rare DiseaseTweet-
Let the conversations continue... Tofersen does not improve ALS symptoms in patients with SOD1 mutations https://t.co/5TVRSeVxgY
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Mashup Score: 5EMERGE trial: Delayed coronary angiogram noninferior for patients with out of hospital cardiac arrest | 2 Minute Medicine - 2 year(s) ago
1. In patients who experienced an out of hospital cardiac arrest with no ST elevations on post-resuscitation electrocardiogram, emergency coronary angiogram was not associated with a better 180-day survival rate with minimal neurologic sequelae when compared to delayed coronary angiogram Evidence Rating Level: 2 (Good) Study Rundown: The most common cause of sudden cardiac death
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
#EMERGEtrial: Delayed #CoronaryAngiogram noninferior for patients w/ #OutOfHospitalCardiacArrest [OHCA) https://t.co/SzhaiIZG3O @2minmed https://t.co/yJy3HEJOsr
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Mashup Score: 6Increased physical activity is a long-term protective factor for dementia | 2 Minute Medicine - 2 year(s) ago
1. Physical activity was significantly associated with a decreased incidence of all-cause dementia and Alzheimer’s disease, irrespective of follow-up length, baseline age and study quality. 2. Physical activity was found to be a protective factor for all-cause dementia and Alzheimer’s disease, even in follow-ups longer than 20 years. Evidence Rating Level: 1 (Excellent) Physical activity
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
Increased #physicalactivity is a long-term protective factor for dementia. #Exercise was found to be a protective factor for all-cause #dementia and Alzheimer’s disease, even in follow-ups longer than 20 years. https://t.co/O1JAeUqI58 https://t.co/BMp0lLQxnh
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Mashup Score: 1Lenvatinib plus pembrolizumab increased survival for advanced endometrial cancer patients when compared to chemotherapy | 2 Minute Medicine - 2 year(s) ago
1. The median progression-free survival and overall survival was longer with lenvatinib plus pembrolizumab than with chemotherapy. 2. Clinically important adverse events in the combination group included hypertension, thyroid dysfunction, colitis and diarrhea Evidence Rating Level: 1 (Excellent) Study Rundown: Advanced endometrial cancer after platinum treatment remains difficult to treat and…
Source: 2 Minute MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
2 minutes on #Lenvatinib plus #pembrolizumab for advanced #endometrialcancer @2minmed https://t.co/tUKT3OKH9u
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Mashup Score: 8Physical activity and sleep may have synergistic effects on health | 2 Minute Medicine - 2 year(s) ago
1. Physical activity levels at or above the WHO guidelines threshold eliminated most of the negative effects of poor sleep on mortality. 2. The negative effects of poor sleep were further amplified with lower levels of physical activity. Evidence Rating Level: 2 (Good) Beyond the independent health effects that physical activity and sleep have on […]
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
Study: #Exercise may reduce some of the negative effects that too little sleep has on mortality. Being sedentary also enhances the negative health effects of lack of sleep. https://t.co/DIpXnNfdDJ #health #wellness https://t.co/x1jbjTGItI
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Mashup Score: 1Vitamin D supplementation not supported to treat first-episode psychosis | 2 Minute Medicine - 2 year(s) ago
1. The DFEND double-blind, randomized controlled trial revealed that Vitamin D supplementation led to no improvements in clinical outcomes at 6-months, as measured by the Positive and Negative Syndrome Scale, among patients with first-episode psychosis compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Recent evidence indicates that individuals with psychosis are more likely…
Source: 2 Minute MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Vitamin D supplementation not supported to treat first-episode psychosis https://t.co/WytqNF6Tee via @MichaelTPratte et al
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Mashup Score: 16Physical activity and sleep may have synergistic effects on health | 2 Minute Medicine - 3 year(s) ago
1. Physical activity levels at or above the WHO guidelines threshold eliminated most of the negative effects of poor sleep on mortality. 2. The negative effects of poor sleep were further amplified with lower levels of physical activity. Evidence Rating Level: 2 (Good) Beyond the independent health effects that physical activity and sleep have on […]
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
Study: #Exercise may reduce some of the negative effects that too little sleep has on mortality. Being sedentary also enhances the negative health effects of lack of sleep. https://t.co/D2Kx8L3wui #health #wellness https://t.co/5igjmukz1N
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Mashup Score: 1Targeted screening not superior to nontargeted screening for human immunodeficiency virus in the emergency department | 2 Minute Medicine - 3 year(s) ago
1. Targeted versus nontargeted HIV screening in the emergency department resulted in a similar number of new HIV diagnoses, yet a lower percentage of testing was performed in the targeted cohorts. Evidence Rating Level: 1 (Excellent) Study Rundown: Diagnosing HIV is a critical public health priority to initiate early treatment and reduce spread from unaware […]
Source: 2 Minute MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
Targeted #HIVscreening not superior to nontargeted screening for human immunodeficiency virus in the emergency department | 2 Minute Medicine https://t.co/VyS6JCfrJQ
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RT @hvanspall: #PROMs in #cardiovascular disease have limited validation of #psychometric properties https://t.co/RZH0NtGycE https://t.co…