Optimizing the treatment of hypothyroidism
Nature Reviews Endocrinology – Daily levothyroxine (LT4) is the standard of care for the treatment of hypothyroidism; however, a small number of patients experience residual symptoms of…
Nature Reviews Endocrinology – Daily levothyroxine (LT4) is the standard of care for the treatment of hypothyroidism; however, a small number of patients experience residual symptoms of…
Nature Reviews Molecular Cell Biology – Verheyen and Gottardi revisit two seminal papers by the Basler, Peifer and Clevers labs elucidating the role of nuclear…
Nature Cancer – Rezvan and colleagues profile the infusion product from individuals with DLBCL treated with CAR T cells and integrate functional profiling by timelapse…
Nature Chemistry – Advances in the development of cytoskeletal-like materials with modular structures and mechanics are pivotal for the engineering of synthetic cells. Now actin-mimetic…
Nature Cancer – Zeiser and colleagues show that CAR T cell therapy results in upregulation of the TGFβ-activated kinase-1 (TAK1)–NF-κB–p38 MAPK pathway in microglia, causing…
Nature Reviews Cancer – This Review provides an introductory guide to artificial intelligence (AI)-based tools for non-computational cancer researchers. Here, Perez-Lopez et al. outline the…
Nature Reviews Cancer – Kong et al. have now shown that Knudson’s two-hit hypothesis can be circumvented through the actions of the glycolytic metabolite methylglyoxal,…
Nature Reviews Cancer – In a ‘publish or perish’ culture, some scientists may resort to questionable research practices or even fraud. Scientific paper mills and…
Nature Reviews Cancer – This Review provides an introductory guide to artificial intelligence (AI)-based tools for non-computational cancer researchers. Here, Perez-Lopez et al. outline the…
Over the coming decades, Africa is predicted to have the greatest increase in the number of older people worldwide. Older people in this region spend…
Nature – Combination of TCR or CAR T cells expressing the engineered CD47 variant 47E with anti-CD47 antibody therapy results in synergistic antitumour efficacy due…