Legionella uses host Rab GTPases and BAP31 to create a unique ER niche
Chadha et al. demonstrate that Legionella pneumophila manipulates host cell membranes to form the Legionella-containing vacuole (LCV), which is distinct from the host rough ER. This transition is driven by host proteins BAP31, GTPases Rab10 and Rab4, and the Legionella effector Lpg1152.