High serum uric acid (SUA) level and kidney dysfunction are known independent risk factors for all-cause mortality and some cause-specific deaths.1-3 When both conditions coexist, as is the case in a substantial portion of the population,1 mortality increases even more.

A male in his mid-60s with immunoglobulin A lambda light chain–restricted multiple myeloma with a “normal” karyotype and plasma cell fluorescence in situ hybridization was treated with bortezomib, lenalidomide, and dexamethasone for 3.5 months with 1 month of daratumumab added with partial response. He underwent autologous peripheral blood stem cell transplantation. The day-58 bone marrow biopsy showed residual plasma cell myeloma with ∼15% light chain–restricted plasma cells showing many enlarged cells with numerous monomorphic and uniformly sized small round bland-appearing nuclei without Dutcher bodies or prominent nucleoli (Figures A and B).

A healthy woman in her late 50s presented to the dermatology clinic for a routine skin cancer screening exam. Her vertex scalp was noted to have a semicircular plaque of scarring alopecia (Figure 1). She reported the scarring was caused by birth trauma. Images from 2 days of life demonstrated caput succedaneum and a ring of skin ulceration (Figure 2) that ultimately led to a permanent halo scalp ring.

A healthy woman in her late 50s presented to the dermatology clinic for a routine skin cancer screening exam. Her vertex scalp was noted to have a semicircular plaque of scarring alopecia (Figure 1). She reported the scarring was caused by birth trauma. Images from 2 days of life demonstrated caput succedaneum and a ring of skin ulceration (Figure 2) that ultimately led to a permanent halo scalp ring.

A 73-year-old woman presented to the emergency department with worsening fatigue, dizziness, and generalized weakness of 2 weeks’ duration. Her medical comorbidities included heart failure with preserved ejection fraction, prior rheumatic fever complicated by severe mitral valve regurgitation after prosthetic mitral valve replacement, acute ischemic stroke, and a history of gastrointestinal (GI) bleeding. Her medications included rivaroxaban, iron supplementation tablet, metoprolol tartrate, and torsemide.

To evaluate the safety of triptans in migraine patients with cardiovascular disease or elevated cardiovascular risk.

An older man presented with retroperitoneal lymphadenopathy, mildly elevated β-human chorionic gonadotropin level, and a complex past medical history. Previous germline testing confirmed the presence of a pathogenic BRCA1 variant. Specifically, he had a past medical history of chronic myeloid leukemia, colorectal carcinoma, melanoma, seminoma, and prostate cancer. A retroperitoneal lymph node biopsy was performed, and histologic and immunohistochemical evaluation demonstrated metastasis from the patient’s previously diagnosed seminoma (Figure).