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Mashup Score: 0Pemphigus Vulgaris - 17 hour(s) ago
A man in his mid-40s was referred with a 2-week history of painful erosions in his mouth followed by spontaneous fragile blisters on his trunk and extremities, resulting in painful erosions. Physical examination demonstrated oral lesions, widespread skin erosions, crusted lesions, and flaccid bullae over his body (Figure 1).
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1State of Gene Therapy for Monogenic Cardiovascular Diseases - 19 hour(s) ago
Over the past 2 decades, significant efforts have been made to advance gene therapy into clinical practice. Although successful examples exist in other fields, gene therapy for the treatment of monogenic cardiovascular diseases lags behind. In this review, we (1) highlight a brief history of gene therapy, (2) distinguish between gene silencing, gene replacement, and gene editing technologies, (3) discuss vector modalities used in the field with a special focus on adeno-associated viruses, (4) provide examples of gene therapy approaches in cardiomyopathies, channelopathies, and familial hypercholesterolemia, and (5) present current challenges and limitations in the gene therapy field.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 034-Year-Old Man With Sudden Epigastric Abdominal Pain - 21 hour(s) ago
A 34-year-old man with a history of multiple episodes of acute pancreatitis complicated by known pseudocysts, fatty liver disease, and polysubstance abuse presented to the emergency department with sudden onset of epigastric abdominal pain, nausea, and vomiting. His symptoms started approximately 45 minutes after eating dinner. He was not taking any medications and denied recent trauma. The patient reported active smoking (19 pack-year history) and consumption of several alcoholic drinks earlier that day.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
View Full-Length Video at: https://youtu.be/zVc4kQTWxsURelated Article Available at: https://mayocl.in/48KdoP8
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Mashup Score: 0Association of a Mediterranean Lifestyle With All-Cause and Cause-Specific Mortality: A Prospective Study from the UK Biobank - 2 day(s) ago
To examine the association between the Mediterranean lifestyle and all-cause, cancer, and cardiovascular disease (CVD) mortality in a British population.
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Mashup Score: 0
To assess the associations of docosahexaenoic acid (DHA), a marine omega-3 fatty acid, with long-term all-cause mortality, cardiovascular (CV) mortality, and cancer mortality.
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Mashup Score: 0Bringing the Potential Benefits of Omega-3 to a Higher Level - 2 day(s) ago
Eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, the main long-chain omega-3 polyunsaturated fatty acids present in seafood, have been proposed for use in the prevention and treatment of cardiovascular diseases (CVDs). Diet is the primary source of protective fatty acids, but personal preferences and dietary restrictions, among other factors, can prevent people from eating a sufficient amount of food rich in EPA and DHA, so adequate intake of omega-3 fatty acids is not always achieved. Therefore, the use of omega-3 supplements containing EPA and DHA can be recommended to increase EPA and DHA to the appropriate levels.
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Mashup Score: 0
Shifting societal attitudes trending toward increased acceptance of transgender people has contributed to a growth in the population of individuals who openly identify as transgender as well as an increase in utilization of gender-affirming surgeries. Therefore, health care providers should work toward increasing their knowledge with respect to the health care needs of the transgender population, particularly given that these individuals often face discrimination in the health care system. Moreover, transgender breast cancer screening rates lag behind breast cancer screening rates for cisgender individuals.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0Vitamin D Supplementation: To D or Not to D? - 3 day(s) ago
Vitamin D was once considered a panacea for a variety of ailments but now is considered by some to be unimportant. As is often the case, the pendulum swings widely from one extreme to the other.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0State of Gene Therapy for Monogenic Cardiovascular Diseases - 4 day(s) ago
Over the past 2 decades, significant efforts have been made to advance gene therapy into clinical practice. Although successful examples exist in other fields, gene therapy for the treatment of monogenic cardiovascular diseases lags behind. In this review, we (1) highlight a brief history of gene therapy, (2) distinguish between gene silencing, gene replacement, and gene editing technologies, (3) discuss vector modalities used in the field with a special focus on adeno-associated viruses, (4) provide examples of gene therapy approaches in cardiomyopathies, channelopathies, and familial hypercholesterolemia, and (5) present current challenges and limitations in the gene therapy field.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General HCPsTweet
Medical images: Pemphigus vulgaris, a potentially severe blistering autoimmune dermatosis characterized by flaccid blisters and erosions on the mucous membranes and/or skin. https://t.co/eKmOpX0b2q https://t.co/buaeFAq3hX