Gao et al. show that the plasma cells (PCs) can be recruited to glioblastoma stem cell (GSC) niches via the CCL2-CCR2 chemokine program and promote glioblastoma growth by regulating GSCs through the IgG-FcγRIIA-AKT-mTOR axis. Blocking PC-mediated stimulation of GSCs represents a promising therapeutic strategy for cancer immunotherapy.
Matthew Matasar, MD, discusses results from a primary analysis of the ELM-1 study that showed the encouraging efficacy and manageable safety of CD20-CD3 bispecific antibody…
Metabolic adaptations are key to cancer cell survival in nutrient-limited microenvironments, but strategies for coping with arginine scarcity are poorly understood. Dunlap et al. use CRISPR…
According to results from a retrospective study, single-agent enfortumab vedotin demonstrated real-world efficacy among previously treated patients with metastatic urothelial carcinoma.
Journal of Neuro-Oncology – Availability data are scarce and primarily retrospective in patients with brain metastasis (BM) from gastrointestinal (GI) cancers. The objective of this…
Dasom (Caroline) Lee, MD, discusses real-world data for second-line axi-cel in relapsed/refractory large B-cell lymphoma.
In this issue of Blood, Banerjee et al1 present a secondary analysis of pooled data from 2 completed SWOG cooperative group trials (SO777 and S1211), showi
ARC is conducting an online survey of patients and caregivers for individuals living with amyloidosis to collect data and information on …
wednesday, february 26 continental breakfast 7-8 a.m. Keynote Session 4 8-8:30 a.m. Session Chair: Antoni Ribas, UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California education…
During our combined 35 years working to advance diagnostic capabilities for cancer—as a pathologist and as a bioinformatician, respectively—we’ve had the opportunity to help build…
On Nov. 5, as the American people expressed their will, electing Donald Trump to a second term, I started to wonder what my friends in…
