Nature Reviews Immunology – A preprint by Xu et al. shows that MHC-pseudotyped retroviruses can reprogramme, activate and expand tumour-specific T cell populations in vivo.
Nature Reviews Endocrinology – Endocrine immune-related adverse events can occur in response to immune checkpoint inhibitors and can be severe. However, in some cancer types,…
Nature Medicine – This analysis of the registry database DESCAR-T of more than 3,000 pediatric and adult patients with hematological malignancies who received CAR T cell…
Nature – Tripotential intermediate progenitor cells are responsible for the local production of GABAergic neurons, oligodendrocyte precursor cells and astrocytes in the human neocortex.
Nature Medicine – In this phase 1 trial, patients with locally advanced or metastatic solid tumors were treated with the individualized mRNA neoantigen-specific immunotherapy (iNeST)…
Nature Medicine – In a large-scale prospective study run across 12 sites in Germany and involving 463,094 women and 119 radiologists, AI-supported screening increased breast…
AAAAI experts explain asthma, exercise-induced bronchoconstriction (EIB) and winter sports.
Nature Communications – IVF protocols are designed for the typical patient with infertility, but personalization can improve clinical outcomes. Here, authors show potential of AI…
Molecular Psychiatry – Dysregulation of neuropilin-2 expression in inhibitory neurons impairs hippocampal circuit development and enhances risk for autism-related behaviors and seizures
A DNA-PK inhibitor can inhibit a tumor cell’s ability to evade detection by preventing targetable molecules from appearing on the surface of a cell.
Nature Biotechnology – Implementation of intellectual property education in academic institutions can result in increased opportunities for protecting intellectual property and limit costs, but to…
