Frontiers | Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke
1 Department of Anesthesiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China 2 State Key Laboratory of Oral Diseases, Department of Oral and Maxillofacial Surgery, National Center for Stomatology and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China Postoperative cognitive dysfunction (POCD) is a prevalent complication that significantly affects