Spatial and molecular profiling of 117 tumors before and after chemotherapy reveals a dynamic tumor ecosystem in ovarian cancer. Launonen et al. identify Myelonets as drivers of CD8+ T cell exhaustion and demonstrate that NECTIN2-TIGIT signaling predicts preclinical immune checkpoint blockade response, unlocking new therapeutic strategies for high-grade serous carcinoma.
Phase 2 data support epcoritamab monotherapy as a promising chemotherapy-free option for older patients with newly diagnosed LBCL.
A CU Cancer Center global oncology leader has returned from Mexico, where he signed the first of many agreements with cancer centers in Latin America.
Huntsman Cancer Institute researchers have identified a gene variant found in a high-altitude Andean population that may predict severity of diseases and responses to treatments…
Johal et al. show that ALDH7A1-deficient cells and mice accumulate lysine metabolites via the saccharopine pathway, which are thought to cause seizures in patients with pyridoxine-dependent…
SAN ANTONIO — Risk-reducing surgery appeared linked with improved outcomes among BRCA mutation carriers diagnosed with early breast cancer, according to study results presented at…
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Risk-reducing surgery improved survival outcomes in younger patients with breast cancer and a germline BRCA mutation.
T-DXd improved PFS vs treatment of physician’s choice in hormone receptor-positive, HER2-low/-ultralow metastatic breast cancer.
Laura J. van ’t Veer, PhD, will receive the William L. McGuire Memorial Lecture Award at this year’s San Antonio Breast Cancer Symposium, scheduled for…
On Dec. 3, the faculty and staff members at the OHSU Knight Cancer Institute received an email from Brian J. Druker, the institution’s star scientist,…
