AJKD Atlas of Renal Pathology: Cellular Variant of Focal Segmental Glomerulosclerosis
The Columbia classification of focal segmental glomerulosclerosis (FSGS) describes 5 variants, of which the cellular variant is the rarest. This variant is more common in children than in adults, and typically presents with nephrotic-range proteinuria. The cellular variant can be diagnosed after excluding collapsing and tip variants, when there is endocapillary hypercellularity involving at least 25% of the tuft of at least one glomerulus, without immune complexes, and typically with extensive foot process effacement.
