A recent study by Ascic et al. demonstrates that in situ reprogramming of tumor cells into conventional dendritic cell (cDC)-like cells using viral-PIB transcription factors creates an immunogenic tumor microenvironment with T cell recruitment and activation. The study highlights the potential of tumor-specific cancer immunotherapy using in vivo reprogrammed cDCs.
DALLAS — In this video from the American Association of Hip and Knee Surgeons Annual Meeting, Robert A. Burnett, MD, discussed results that showed repeat…
Hlavaty et al. demonstrate that, when cancer cells with high expression of ACSS1 are exposed to acetate, it causes significant metabolic rewiring that promotes cancer cell…
Seed et al. explore a cohort of PARPi-treated advanced prostate cancers, studying plasma cell-free DNA samples for genomic alterations that provide drug resistance. They find multiple…
Seed et al. explore a cohort of PARPi-treated advanced prostate cancers, studying plasma cell-free DNA samples for genomic alterations that provide drug resistance. They find multiple…
Following on from the discovery that innate immune pathways are shared widely across the tree of life comes another surprise: Hobbs et al. show that…
Combinations of the highly polymorphic KIR and HLA-I genes are associated with numerous human diseases. Interpreting these associations requires a molecular understanding of the multiple…
Babcock Dairy of Madison, Wisconsin, is voluntarily expanding its recall on Orange Custard Chocolate Chip ice cream that may be labeled as Chocolate Peanut Butter.…
In this article, Thomaidou and colleagues show that miR-124 instructs the reprogramming switch of astrocytes toward an immature neuronal fate by targeting the RNA-binding protein…
Text for H.R.9778 – 118th Congress (2023-2024): PAVE Act
Little did California businesses know that they were cosigners on the state’s nearly $20 billion loan from the federal government that was used to cover…
