To assess whether viral, bacterial, metabolic, and autoimmune diseases are missed by conventional diagnostics among children with severe acute encephalopathy in sub-Saharan Africa.
Acta Neuropathologica – Aging is associated with cell senescence and is the major risk factor for AD. We characterized premature cell senescence in postmortem brains…
INTRODUCTION Genome-wide association studies have identified over 70 genetic loci associated with late-onset Alzheimer’s disease (LOAD), but few candidate polymorphisms have been functionally assess…
Objective While a substantial body of research describes the disabling impacts of migraine attacks, less research has described the impacts of migraine on physi…
Barbour et al. report that seizures worsen cognitive decline and excitatory:inhibitory imbalance in patients with Alzheimer’s disease. Chronic treatment wi
RAB32 Ser71Arg is a novel genetic risk factor for Parkinson’s disease, with reduced penetrance. The variant was found in individuals with Parkinson’s disease from multiple…
Background: This study investigates clinical and biomarker differences between standard interval dosing (SID) and extended interval dosing (EID) of ocrelizumab …
Huang et al. examine how a person’s genetic make-up affects their immune response to Epstein-Barr virus and how this relationship affects risk for multiple
Sánchez-Juan et al. reveal an association between serum GFAP levels and post-mortem tau pathology in patients with dementia, independent of amyloid deposit
Annals of Neurology is a leading neurology journal from the American Neurological Association focusing on diseases of the human nervous system.
BACKGROUND Alzheimer’s disease (AD) prevalence increases with age, yet a small fraction of the population reaches ages > 100 years without cognitive decline. We studied…
