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Mashup Score: 1DNA and protein HIV vaccines: how should we mix it? - 2 day(s) ago
The development of an effective HIV vaccine is crucial for controlling the HIV epidemic. UNAIDS estimated that there were 1·5 million new HIV infections and 650 000 deaths in 2021.1 Despite decades of vaccine research and ten phase 2b/3 clinical trials testing various vaccine concepts, a protective vaccine is still needed.2 Therefore, a return to fundamental research and testing of new concepts is necessary. This task is considerable given the number of immunogens, emerging vaccine platforms, and combinations that could be tested.
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Mashup Score: 40
Both vaccine regimens were safe, warranting evaluation in larger trials.
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Mashup Score: 98People First Charter - 9 day(s) ago
People First Charter
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Mashup Score: 8The Lancet HIV, May 2024, Volume 11, Issue 5, Pages e273-e344 - 10 day(s) ago
Explore the current issue of The Lancet HIV, a monthly journal dedicated to publishing content that advocates for change in or illuminates HIV clinical practice
Source: www.thelancet.comCategories: General Medicine News, HIV/AIDSTweet-
Our May issue is ready! Featuring bictegravir in children, metabolic changes during ART, the HVTN 124 trial, and incentives to improve viral suppression in people who inject drugs. Cover: ilustratoro (IG) based on Viewpoint on collective ART protection https://t.co/RSRoKKjabo https://t.co/VwJQrVcEGo
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Mashup Score: 0Who benefits from frequent asymptomatic STI screening? - 16 day(s) ago
How often should asymptomatic gay, bisexual and other men who have sex with men (GBM) and transgender women be screened for gonorrhoea and chlamydia, if at all? Incidences of sexually transmitted infections (STIs) have been rising steadily for some years and many countries have responded by doubling down on more frequent screening in those at risk. GBM and transgender women who take HIV pre-exposure prophylaxis (PrEP) are among those most likely to acquire STIs, and most guidelines recommend testing every 3 months in this group.
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Mashup Score: 8
We failed to show that non-screening for N gonorrhoeae and C trachomatis is non-inferior to 3 × 3 screening in MSM and transgender women taking PrEP in Belgium. However, screening was associated with higher antibiotic consumption and had no effect on the incidence of N gonorrhoeae. Further research is needed to assess the benefits and harms of N gonorrhoeae and C trachomatis screening in this population.
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Mashup Score: 0Evidence with 95-95-95 that ambitious is feasible - 21 day(s) ago
When proposed a decade ago, the UNAIDS 90-90-90 targets were described as aggressive, ambitious, and daunting.1 Nevertheless, these milestones have had a profound effect on HIV responses, galvanizing efforts globally. In The Lancet HIV, Madisa Mine and colleagues2 provide empirical evidence that Botswana, which has one of the highest global prevalences of HIV (one in five adults are living with HIV), has achieved the 95-95-95 targets in 2021, 4 years ahead of the 2025 deadline. The Fifth Botswana AIDS Impact Survey (BAIS V) showed that 92% of people living with HIV were virally suppressed, which is above the 86% goal (extrapolated from 95-95-95).
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 22Progress towards the UNAIDS 95-95-95 targets in the Fifth Botswana AIDS Impact Survey (BAIS V 2021): a nationally representative survey - 21 day(s) ago
BAIS V is the first population-based survey worldwide to report the achievement of the UNAIDS 95-95-95 goals, both overall and among women. Strategies to reach undiagnosed men and young people, including young women, are needed.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 4Drew Voetsch and Robert Selato on achieving the 95-95-95 UNAIDS goals in Botswana - The Lancet HIV in conversation with - 28 day(s) ago
Deputy Editor Adrian Gonzalez interviews Drew Voetsch (Division of Global HIV and TB, US Centers for Disease Control and Prevention, USA) and Robert Selato (National AIDS and Health Promotion Agency, Gaborone, Botswana) on Botswana´s accomplishments and progress towards achieving the UNAIDS 95 targets.Read the full article:https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(24)00003-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhiv
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Mashup Score: 11
Study data support using long-acting cabotegravir or long-acting rilpivirine, given every 4 weeks or 8 weeks, per the adult dosing regimens, in virologically suppressed adolescents aged 12 years and older and weighing at least 35 kg.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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