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Mashup Score: 10Short-term outcomes after third-time lung transplantation: A single institution experience - 1 day(s) ago
Reoperative lung transplantation (LTx) survival has improved over time such that a growing number of patients may present for third-time LTx (L3Tx). To understand the safety of L3Tx, we evaluated perioperative outcomes and 3-year survival after L3Tx at a high-volume US LTx center.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 16
To date, no pediatric studies have highlighted the impact of center’s ventricular assist device (VAD) volumes on post implant outcomes.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 12
Cardiac metabolism is altered in heart failure and ischemia-reperfusion injury states. We hypothesized that metabolomic profiling during ex situ normothermic perfusion before heart transplantation (HT) would lend insight into myocardial substrate utilization and report on subclinical and clinical allograft dysfunction risk.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet-
Metabolomic Profiling During Ex-situ Normothermic Perfusion Prior to Heart Transplantation Defines Patterns of Substrate Utilization & Correlates w Markers of Allograft Injury @laurentrubymd @_adevore @jacobniall @SvatiShah cc @ahajduczok @rachkataria đź”—: https://t.co/7jCkMAQpbf https://t.co/nOGrC0HVf4
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Mashup Score: 10JHLT: The Podcast: Episode 42: May 2024 - 8 day(s) ago
On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the May issue of The Journal of Heart and Lung Transplantation. Digital Media Editor David Schibilsky, MD, a cardiothoracic surgeon from Freiburg, Germany, hosts this episode.  First, Dr. Schibilsky and Digital Media Editor Erika Lease, MD, interview their first guest, Helen A. Hannan, the podcast’s first-ever undergraduate pre-medical guest, from the University of Michigan. Helen was the lead author on the study “.” The study noted that prior research in utilization of kidneys from donors with Hepatitis C had shown disparities due to gender and education—and wanted to see if this was the case in heart and lung donors as well.  Drs. Schibilsky and Lease chat with Helen about the findings of the study, including some of the interesting differences shown between heart and lung recipients, and the ramifications for better patient discussions at the clinical level.  Next, Dr. Schibilsky and Dig
Source: thejhlt.libsyn.comCategories: General Medicine News, Cardiology News and JournTweet-
May #JHLTThePodcast is out! ▶️ Racial and gender disparities in #HepatitisC+ hearts and lungs with Helen Hannan, a @UMich undergraduate ▶️ #Metabolomic profiling during #NRP before #HTX and its ability to predict #allograft injury with @laurentrubymd 🎧: https://t.co/iA4s4lG0ka https://t.co/yzP6e2oakh
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Mashup Score: 1
Adult T-cell leukemia/lymphoma (ATLL) is a rare disease caused by the human T-lymphotropic virus (HTLV). Only 4% of patients infected with HTLV contract ATLL, and most take decades to present with malignancy. Herein, we present a rare case of ATLL following a heart transplantation.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet-
Acute T cell leukemia in a stable recipient of a heart transplantation. The authors recommend preop survey & regular monitoring of HTLV-1/2 carrier recipients after ❤️tx, given lack of established chemotherapy/antivrial agents for such patients. 🔗 https://t.co/vgbqZ90yrZ https://t.co/bBIhj1JAMH
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Mashup Score: 2
To verify whether the new hemodynamic definition of pulmonary hypertension (PH) has any implication in treatment of Chronic Thrombo-Embolic Pulmonary Disease (CTEPD) patients without PH, we retrospectively analysed the clinical and functional changes determined by pulmonary endarterectomy (PEA) in 63 CTEPD patients without PH who underwent surgery at our center, comparing those in whom the hemodynamic diagnosis of PH met recent guideline recommendations versus those in whom the diagnosis only met previous hemodynamic thresholds.
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Mashup Score: 7Blockade of BLyS inhibits B-cell responses and antibody production for the prevention of chronic transplant rejection - 15 day(s) ago
Chronic rejection, closely related to the activation of B cells and donor-specific antibody (DSA) production, has unsatisfactory therapeutic outcomes. B lymphocyte stimulator (BLyS) is a major regulatory factor that controls the activation and differentiation of B cells. However, it remains unclear whether BLyS blockade can regulate B and plasma cells in the transplantation setting and affect chronic rejection. Here, we investigated the efficacy of the BLyS inhibitors belimumab and telitacicept in controlling B-cell response and preventing chronic rejection.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet-
BLyS inhibitors were effective in inhibiting B-cell activation/differentiation, reducing antibody production & prolonging allograft survival. BLyS inhibitors could be used for prevention of chronic rejection in practice. cc @ahajduczok @rachkataria đź”— https://t.co/4jzVWBwp8e https://t.co/uooq3wUYCd
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Mashup Score: 3
Dear Editor,
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 21
The physiological response of the right ventricle (RV) following left ventricular assist device (LVAD) implantation is difficult to predict. We aimed to investigate RV geometric and functional changes after LVAD insertion and their effects on clinical outcomes.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet-
Changes in RV dimensions are not included in risk predictions post LVAD. A non-adapted RV was associated with alterations TV & RV geometry, leading to worsening TR. This may help identify patients that may be refractory to LVAD therapy. @HideyukiHayash6 đź”— https://t.co/m0vkYBMX3T https://t.co/cB6Y6O1xjn
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Mashup Score: 5Development and validation of primary graft dysfunction predictive algorithm for lung transplant candidates - 20 day(s) ago
Primary graft dysfunction (PGD) is the leading cause of early morbidity and mortality after lung transplantation. Accurate prediction of PGD risk could inform donor approaches and perioperative care planning. We sought to develop a clinically useful, generalizable PGD prediction model to aid in transplant decision-making.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
Third-time lung transplantation recipients, despite increased operative complexity, demonstrate similar three-year survival compared to matched first-time and repeat lung transplant recipients. @VikramFGupta đź”—: https://t.co/SpoinpKzlu