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Mashup Score: 52Blood Pressure Reduction in ICH: Time is Still Brain - 6 day(s) ago
Previous analyses of randomized clinical trials (RCT) suggest early blood pressure lowering in acute, spontaneous intracerebral hemorrhage (ICH) may improve functional outcomes and reduce hematoma expansion (HE). However, previous research was limited to post hoc analyses of individual t rials, and there are limited data investigating the general relationship between time to achieving target systolic blood pressure (SBP) and outcomes in acute ICH. Wang et al. aimed to assess whether an earlier time to
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Mashup Score: 46Near-Infrared II Photobiomodulation Preconditioning Ameliorates Stroke Injury via Phosphorylation of eNOS - 6 day(s) ago
BACKGROUND: The current management of patients with stroke with intravenous thrombolysis and endovascular thrombectomy is effective only when it is timely performed on an appropriately selected but m
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Mashup Score: 8Mapping the Ecological Terrain of Stroke Prehospital Delay: A Nationwide Registry Study - 10 day(s) ago
BACKGROUND: Delays in hospital presentation limit access to acute stroke treatments. While prior research has focused on patient-level factors, broader ecological and social determinants have not bee
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Mashup Score: 22Combining Early Ischemic Change and Collateral Extent for Functional Outcomes After Endovascular Therapy: An Analysis From AcT Trial - 10 day(s) ago
BACKGROUND: Early ischemic change and collateral extent are colinear with ischemic core volume (ICV). We investigated the relationship between a combined score using the Alberta Stroke Program Early
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Mashup Score: 10
European Stroke Organisation Conference May 15 – 17, 2024 Chaired by Zuzan Gdovinova (Kosice, Slovakia) and Alison Halliday (United Kingdom), the speakers in this session addressed the symbiotic relationship between neurologists and cardiologists in secondary stroke prevention. Luciano Sposato (London, Canada) discussed the WSO BEAT project to build an interdisciplinary brain-heart team. WSO BEAT is a program aimed to assist cardiologists and neurologists to diagnose and manage ischemic stroke or TIA.
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Mashup Score: 59
There remains an ongoing question in stroke care regarding the utility of thrombolytics in patients with large vessel occlusion (LVO) undergoing mechanical thrombectomy (MT). Multiple large clinical trials have looked at this with mixed results, but a recent meta-analysis including 6 of these trials (SKIP, DEVT, MR CLEAN-NO IV, SWIFT-DIRECT, DIRECT SAFE) failed to demonstrate benefit of MT alone. Thus, current guidelines recommend giving thrombolytics to eligible patients prior to MT. Tirofiban is a
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Mashup Score: 1
Department of Pediatric Neurology, Oregon Health & Science University, Portland (J.L.W.). Department of Pediatric Neurology, Providence Health and Services, Portland, OR (A.C.). Correspondence to: Alexis N. Simpkins, MD, PhD, MSCR, Director of Vascular Neurology Research and the SkRIPT Research Program, Department of Neurology, 127 S San Vicente Blvd, Los Angeles, CA 90048. Email Department of Vascular Neurology, Cedars Sinai Medical Center, Los Angeles, CA (A.N.S.). Department of Neurology, University
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Mashup Score: 9
BACKGROUND: Extreme temperatures contribute significantly to global mortality. While previous studies on temperature and stroke-specific outcomes presented conflicting results, these studies were pre
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Mashup Score: 19ESOC 2024: “Are Earlier Interventions the Key to the Conundrum of Intracerebral Haemorrhage?” - 11 day(s) ago
European Stroke Organisation Conference May 15 – 17, 2024 Session: Are Earlier Interventions the Key to the Conundrum of Intracerebral Haemorrhage? Time is critical in intracerebral hemorrhage. Most hematoma expansion occurs with 3 hours of symptom onset; edema formation then peaks at 7-10 days. This session explored the evidence behind giving treatments quickly, how quickly they should be delivered, and how care bundles lead to effective delivery. Else Sandset began by discussing blood pressure management
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Mashup Score: 20
European Stroke Organisation Conference May 15 – 17, 2024 Sonia Alamowitch from Paris, France, and Simona Sacco from L’Aquila, Italy, chaired this session that explored the grey areas of thrombolysis in acute ischemic stroke. David Seiffge (Bern, Switzerland) kicked off the session with a talk on “Intravenous thrombolysis in patients pretreated with anticoagulants.” Seiffge summarized the evidence on this topic which has been emerging in the last years. Despite oral anticoagulation, patients with atrial
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Blood Pressure Reduction in ICH: Time is Still Brain In this #BloggingStroke post, @wechsler_paul discusses #Stroke article "Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage." #AHAJournals https://t.co/2UT9vUJolx https://t.co/fOHfHFGDG8