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Mashup Score: 6Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus: JACC: CardioOncology State-of-the-Art Review - 5 hour(s) ago
AbstractAlthough recent advancements in cancer therapies have extended the lifespan of patients with cancer, they have also introduced new challenges, including chronic health issues such as cardio…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 94
Researchers at Case Western Reserve University, University Hospitals and Houston Methodist will harness the power of artificial intelligence (AI) to more accurately predict risk of heart failure and other cardiovascular events, including estimating when an adverse event might occur, by developing an AI model that “learns” from patient scans.
Source: www.newswise.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 19Abstract 4145231: Immuno-Hematologic Aging and Resilience: Novel Markers of Cardiovascular Risk | Circulation - 3 month(s) ago
Background: Aging is a complex process that affects various organ systems, including the cardiovascular (CV) and immune systems. Chronologic age does not fully capture the heterogeneity in biological aging, and studies suggest that the immuno-hematologic (IH) systems play a critical role in the aging process and may contribute to CV disease. However, the relationship between IH aging and CV risk is not well characterized. Routine complete blood count with differential (CBC-diff) is a widely available test that assesses blood components. Its utility in capturing biological age and association with CV risk has not been explored. Methods: Using data from adult participants in NHANES 1999-2018, we trained an XGBoost model to predict chronologic age using 20 variables obtained from CBC-diff. The model was trained on 50% of the data (n=26,677), and the remaining 50% (n=26,677) was used to predict age (IHAGE). We calculated the difference between IHAGE and chronologic age (ΔAge), and categori
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3The Benefits of Intensive Versus Standard Blood Pressure Treatment According to Fine Particulate Matter Air Pollution Exposure | Hypertension - 3 month(s) ago
Fine particulate matter <2.5 µm (PM2.5) air pollution is implicated in global mortality, especially from cardiovascular causes. A large body of evidence suggests a link between PM2.5 and elevation in blood pressure (BP), with the latter implicated as a potential mediator of cardiovascular events. We sought to determine if the outcomes of intensive BP lowering (systolic BP <120 mm Hg) on cardiovascular events are modified by PM2.5 exposure in the SPRINT (Systolic BP Intervention Trial). We linked annual PM2.5 exposure estimates derived from an integrated model to subjects participating in SPRINT. We evaluated the effect of intensive BP lowering by PM2.5 exposure on the primary outcome in SPRINT using cox-proportional hazard models. A total of 9286 participants were linked to PM2.5 levels (mean age 68±9 years). Intensive BP-lowering decreased risk of the primary outcome more among patients exposed to higher PM2.5 (Pinteraction=0.047). The estimate for lowering of primary outcome was nume
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 44
Background: Finerenone significantly reduced the risk of CV and adverse kidney outcomes vs placebo in patients with CKD and T2D in FIDELITY, a prespecified pooled analysis of the phase III FIDELIO-DKD and FIGARO-DKD trials. Exposure to particulate matter air pollution ≤2.5 microns (PM2.5) is established as the world’s leading environmental risk factor and is implicated in CV and kidney events. This FIDELITY post-hoc subanalysis aimed to examine the effect of finerenone across varying levels of PM2.5 exposure. Methods: Patients in FIDELITY were on optimized renin–angiotensin system inhibition and randomized 1:1 to finerenone or placebo. Key outcomes included composite CV (CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure), composite kidney (kidney failure, sustained ≥57% decrease in estimated glomerular filtration rate from baseline over at least 4 weeks, or kidney-related death), and combined composite CV and kidney. Participants were assig
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 16Too Hot To Sleep? - Videos from The Weather Channel - 3 month(s) ago
For the first time, an annual study on climate and health has looked into sleep loss caused by rising nighttime temperatures. Watch this video to see just how much sleep we’re losing around the world and hear from a cardiologist on how that could hurt our health. – Videos from The Weather Channel | weather.com
Source: weather.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3
Scientific Reports – Leveraging calcium score CT radiomics for heart failure risk prediction
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 62JACC: Advances: Vol 3, No 9_Part_2 - 4 month(s) ago
Franca Dipaola, Raffaello Furlan, et. al. JACC Adv. 2024 Sep, 3 (9_Part_2) 101072. JACC Adv. 2024 Sep, 3 (9_Part_2) 101202. JACC Adv. 2024 Sep, 3 (9_Part_2) 101182. JACC Adv. 2024 Sep, 3 (9_Part_2) 100890. JACC Adv. 2024 Sep, 3 (9_Part_2) 100889. JACC Adv. 2024 Sep, 3 (9_Part_2) 101180. JACC Adv. 2024 Sep, 3 (9_Part_2) 101185. JACC Adv. 2024 Sep, 3 (9_Part_2) 100998. JACC Adv. 2024 Sep, 3 (9_Part_2) 100999. JACC Adv. 2024 Sep, 3 (9_Part_2) 101176. JACC Adv. 2024 Sep, 3 (9_Part_2) 101178. JACC Adv. 2024
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 60JACC: Advances: Vol 3, No 9_Part_2 - 4 month(s) ago
Franca Dipaola, Raffaello Furlan, et. al. JACC Adv. 2024 Sep, 3 (9_Part_2) 101072. JACC Adv. 2024 Sep, 3 (9_Part_2) 101202. JACC Adv. 2024 Sep, 3 (9_Part_2) 101182. JACC Adv. 2024 Sep, 3 (9_Part_2) 100890. JACC Adv. 2024 Sep, 3 (9_Part_2) 100889. JACC Adv. 2024 Sep, 3 (9_Part_2) 101180. JACC Adv. 2024 Sep, 3 (9_Part_2) 101185. JACC Adv. 2024 Sep, 3 (9_Part_2) 100998. JACC Adv. 2024 Sep, 3 (9_Part_2) 100999. JACC Adv. 2024 Sep, 3 (9_Part_2) 101176. JACC Adv. 2024 Sep, 3 (9_Part_2) 101178. JACC Adv. 2024
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 42
AbstractBackgroundRecent studies have used basic epicardial adipose tissue (EAT) assessments (eg, volume and mean Hounsfield unit [HU]) to predict risk of atherosclerosis-related, major adverse car…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
Honored to have contributed to 3 papers in the special #JACCCardioOnc issue on SDOH: Air Pollution State-of-the-Art Review https://t.co/1K84zeNOjT Walkability and CV risk in cancer https://t.co/dMzg5vd65O Polysocial Risk Score https://t.co/SWzKoRQsUI https://t.co/j1c8ppCM7H