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Mashup Score: 75
In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs. | In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs.
Source: www.fiercepharma.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 73
In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs. | In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs.
Source: www.fiercepharma.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 7A comment regarding the paper “Adverse Event Reporting in Randomized Clinical Trials for Multiple Myeloma” - 12 month(s) ago
This is a very interesting article that should kindle in-depth conversations about the descriptions we use to summarize clinical trials in myeloma. The overarching message of this paper is that it is not uncommon to minimize toxicities, even when some clearly have a significant impact on patients. Some things have always bothered me, such as how language can minimize toxicity or seem outright erroneous, and this paper is important documentation. I have some points of agreement with the interpretation but also some of disagreement. I realize the authors have much more to say as the paper is a medical publication focused on the data presented, but this paper stirred many thoughts. I will consider it a conversation starter. Let me explain.
Source: rafaelfonseca.substack.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 4
Must-read paper- clinical trials can be largely predicted by the activity of individual drugs. The paper is careful, stating that “additives” are not necessarily bad. So, how did the myeloma trial studied here fare? Here is a modified Fig 3 to only show MM trial data, #mmsm 1/xQuoteNew paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy,…
Source: x.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0The shady statistics behind the war on painkillers - 1 year(s) ago
The government has doubled down on failed policies, citing deeply flawed studies and misrepresenting data.
Source: Reason.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 6Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial - 1 year(s) ago
Nature Medicine – In the first-in-human trial of elranatamab, patients with refractory or relapsed multiple myeloma who received the bispecific antibody against BCMA and CD3 experienced no…
Source: www.nature.comCategories: Latest Headlines, Partners & KOLsTweet-
RT @NBahlis: Out in today @NatureMedicine, https://t.co/TuvTDSldU6 FIH phase 1 trial with Elranatamab in R/R multiple myeloma defining the…
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Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial | Nature Medicine #myeloma https://t.co/gLWfEEVTt2
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Mashup Score: 0Elranatamab for Relapsed or Refractory Multiple Myeloma - 1 year(s) ago
Read it now on PracticeUpdate.com
Source: www.practiceupdate.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Infections After Bispecific Antibodies in Patients With Myeloma - 1 year(s) ago
Read it now on PracticeUpdate.com
Source: www.practiceupdate.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
Endometriosis diagnostics. Tumor detection. Blood-based biomarkers. Bone repair. These are just a handful of the medical solutions Arizona State University researchers and Mayo Clinic doctors aim to
Source: news.asu.eduCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Dara-CVRd as Induction and Extended Consolidation Improves Outcomes in Patients With Ultra–High-Risk Multiple Myeloma - 1 year(s) ago
Written by Rafael Fonseca MD
Source: PracticeUpdateCategories: Hem/Oncs, Latest HeadlinesTweet
CART & risk of T-cell lymphoma- important not to blow out of proportion. Many Rxs carry a risk of secondary malignancies -the most immediate threat is the cancer. As @akeithstewart stated - a storm in a glass of water? 12/7,946 pts treated (0.15%) #mmsm https://t.co/7TdpJT00VN