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Mashup Score: 56Sepsis-Induced myocardial dysfunction: heterogeneity of functional effects and clinical significance - 16 day(s) ago
Sepsis is a life-threatening disease state characterized by organ dysfunction and a dysregulated response to infection. The heart is one of the many organs affected by sepsis, in an entity termed sepsis-induced cardiomyopathy. This was initially used to describe a reversible depression in ejection fraction with ventricular dilation but advances in echocardiography and introduction of new techniques such as speckle tracking have led to descriptions of other common abnormalities in cardiac function associated with sepsis. This includes not only depression of systolic function, but also supranormal ejection fraction, diastolic dysfunction, and right ventricular dysfunction. These reports have led to inconsistent definitions of sepsis-induced cardiomyopathy. Just as there is heterogeneity among patients with sepsis, there is heterogeneity in the cardiac response; thus resuscitating these patients with a single approach is likely suboptimal. Many factors affect the heart in sepsis including
Source: www.frontiersin.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 9LAICON National 2024 Dr D Prabhakar - 1 month(s) ago
LAICON National 2024 Video Bite from Dr D Prabhakar
Source: www.youtube.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 9Management of Resistant Hypertension - 1 month(s) ago
Resistant hypertension (RH) is a severe form of hypertension associated with increased cardiovascular risk. Although true RH affects less than 10% of the patients receiving antihypertensive therapy, the absolute number is high and continues to increase. The workup of these patients requires screening for secondary hypertension and pseudoresistance, including poor adherence to prescribed medicines and the white-coat phenomenon. The treatment of RH consists of lifestyle modifications and pharmacological therapies. Lifestyle modifications include dietary adjustments, weight loss, physical activity, and limiting alcohol consumption; pharmacological therapies include diuretics, mineralocorticoid receptor antagonists, beta blockers, angiotensin receptor–neprilysin inhibitors, and others. Over the last 15 years, interventional approaches have emerged as adjunct treatment options; we highlight catheter-based renal denervation. This review summarizes the rationales and latest clinical evidence
Source: www.annualreviews.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 14
Cardiovascular Drugs and Therapy – Hyperkalaemia is one of the most common electrolyte disorders in patients with cardiovascular disease (CVD). The true burden of hyperkalaemia in the real-world…
Source: link.springer.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 29Novel drug therapies for atrial fibrillation - 2 month(s) ago
Nature Reviews Cardiology – Atrial fibrillation is the most common sustained arrhythmia and imposes a substantial burden on patients and health-care providers. Clinical evidence suggests that…
Source: www.nature.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 0Lithotripsy for Mitral Valve Stenosis: What's the Promise? - 2 month(s) ago
The new technology seems promising for patients with severe calcific mitral stenosis who cannot undergo surgery or TAVR, but more studies are needed.
Source: www.medscape.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 2FDA Says Eating Yogurt May Reduce Diabetes Risk - 2 month(s) ago
Products will be allowed to carry claims as long as they don’t mislead consumers
Source: www.medpagetoday.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 29
Infective endocarditis (IE) is a severe cardiac complication with high mortality rates, especially when surgical intervention is delayed or absent. This review addresses the expanding role of surgery in managing IE, focusing on the variation in surgical treatment rates, the impact of patient demographics, and the effectiveness of different surgical approaches. Despite varying global data, a notable increase in surgical interventions for IE is evident, with over 50% of patients undergoing surgery in tertiary centres. This review synthesizes information from focused literature searches up to July 2023, covering preoperative to postoperative considerations and surgical strategies for IE. Key preoperative concerns include accurate diagnosis, appropriate antimicrobial treatment, and the timing of surgery, which is particularly crucial for patients with heart failure or at risk of embolism. Surgical approaches vary based on valve involvement, with mitral valve repair showing promising outcom
Source: www.mdpi.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 109
Abstract. Fluid overload has been associated with morbidity and mortality in various clinical scenarios including heart failure and critical illness. It exerts pathologic sequelae in almost all the organ systems. Proper management of patients with fluid overload requires knowledge of the underlying pathophysiology, objective evaluation of volume status, selection of appropriate therapeutic options, and maintenance and modulation of tissue perfusion. There are several methods to appraise volume status but none without limitations. In this review, we discuss the diagnostic utility, prognostic significance, and shortcomings of various bedside tools in the detection of fluid overload and evaluation of hemodynamic status. These include clinical examination, biomarkers, blood volume assessment, bioimpedance analysis, point-of-care ultrasound, and remote pulmonary pressure monitoring. In our opinion, clinicians must adopt a multiparametric approach offsetting the limitations of individual met
Source: karger.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 128Management of Resistant Hypertension—An Update - 2 month(s) ago
This JAMA Internal Medicine Clinical Insights review provides an update on the current recommendations for resistant hypertension management.
Source: jamanetwork.comCategories: General Medicine News, Cardiologists1Tweet
RT @ZHeart11768530: 🔴 Echocardiographic features in patients with sepsis #OpenAccess #2023review https://t.co/ai3AQhm08s #CardioEd #Cardi…