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Mashup Score: 7
Learn about how human resources information and trainings offered through the graduate medical education programs help facilitate a world-class experience.
Source: www.massgeneralbrigham.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 24Structure peer review to make it more robust - 24 day(s) ago
Nature – Everyone who reviews a manuscript should answer a transparent set of questions, to ensure that scientific literature is subject to reliable quality control.
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 14SGLT2i vs Sulfonylureas for Gout Prevention Among Patients With Type 2 Diabetes Receiving Metformin - 24 day(s) ago
This cohort study uses target trial emulation to evaluate risk of incident gout and rate of recurrent gout flares in patients with type 2 diabetes initiating sodium-glucose cotransporter-2 inhibitors (SGLT2i) vs sulfonylurea.
Source: jamanetwork.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 100
Background Genome sequencing of large biobanks from under-represented ancestries provides a valuable resource for the interrogation of Mendelian disease burden at world population level, complementing small-scale familial studies. Methods Here, we interrogate 6045 whole genomes from Qatar—a Middle Eastern population with high consanguinity and understudied mutational burden—enrolled at the national Biobank and phenotyped for 58 clinically-relevant quantitative traits. We examine a curated set of 2648 Mendelian genes from 20 panels, annotating known and novel pathogenic variants and assessing their penetrance and impact on the measured traits. Results We find that 62.5% of participants are carriers of at least 1 known pathogenic variant relating to recessive conditions, with homozygosity observed in 1 in 150 subjects (0.6%) for which Peninsular Arabs are particularly enriched versus other ancestries (5.8-fold). On average, 52.3 loss-of-function variants were found per genome, 6.5 of whi
Source: link.springer.comCategories: General Medicine News, CardiologistsTweet-
Genetic variation is relatively poorly studied in the Middle East, particularly where endogamy and consanguinity are more common. Among 6K WGS in Qatar, 2 in 3 (!) was a carrier for a pathogenic mutation for an autosomal recessive condition. https://t.co/bFE8Ws93Jo… https://t.co/WgOOOftOS5 https://t.co/PuXc2nxQuI
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Mashup Score: 11Vertex to buy Alpine Immune Sciences for $4.9 billion - 30 day(s) ago
Vertex Pharmaceuticals will buy Alpine Immune Sciences, a maker of protein-based medicines that harness the immune system, for $4.9 billion.
Source: www.statnews.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 109Cumulative Diastolic Blood Pressure Burden in Normal Systolic Blood Pressure and Cardiovascular Disease - 30 day(s) ago
BACKGROUND: The clinical significance of isolated diastolic hypertension defined by the 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines remains inconsist
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 11Vertex to buy Alpine Immune Sciences for $4.9 billion - 30 day(s) ago
Vertex Pharmaceuticals will buy Alpine Immune Sciences, a maker of protein-based medicines that harness the immune system, for $4.9 billion.
Source: www.statnews.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 109Cumulative Diastolic Blood Pressure Burden in Normal Systolic Blood Pressure and Cardiovascular Disease - 1 month(s) ago
BACKGROUND: The clinical significance of isolated diastolic hypertension defined by the 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines remains inconsist
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 109Cumulative Diastolic Blood Pressure Burden in Normal Systolic Blood Pressure and Cardiovascular Disease - 1 month(s) ago
BACKGROUND: The clinical significance of isolated diastolic hypertension defined by the 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines remains inconsist
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1Abstract 13604: No Longer Idiopathic: A Case of Recurrent Pericarditis in a Military Recruit - 1 month(s) ago
A 19 year-old man who is a military cadet and also a competitive gymnast presented during boot camp with one week of progressive chest pain and shortness of breath associated with fevers, malaise, an
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
While our residents are amazing, I think Caitlyn Clark should be paid more than PGY-scale salary https://t.co/MCezm7mDac https://t.co/fQJMNmcnBc