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Mashup Score: 157
Nature Reviews Immunology – This Perspective discusses current knowledge of the diverse roles played by different macrophage populations within the Mycobacterium tuberculosis-infected lung. The…
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Mashup Score: 114
Nature Reviews Immunology – This Review summarizes mechanisms for the regulation of cGAS–STING signalling, describes its crosstalk with other signalling pathways, and outlines the diverse…
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Mashup Score: 58
Nature Reviews Immunology – This Review discusses recent advances in our understanding of the biology of endogenous tissue regeneration in the thymus, highlighting the clinical implications of poor…
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Mashup Score: 88IL-22 protects against stress-induced anxiety - 2 month(s) ago
Nature Reviews Immunology – Stress-induced gut leakage and immune activation lead to the release of IL-22, which acts directly on septal neurons in the brain to dampen their activation and protect…
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Mashup Score: 396Cancer immune evasion, immunoediting and intratumour heterogeneity - 2 month(s) ago
Nature Reviews Immunology – Here the authors describe the different ways that cancer cells evade the immune system and how these mechanisms impact immunoediting and tumour clonality. They suggest…
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Mashup Score: 9Transposon-derived decoy fine-tunes IFN responses - 2 month(s) ago
Nature Reviews Immunology – A transposon-derived isoform of the type I interferon (IFN) receptor IFNAR2 can serve as a decoy receptor to regulate IFN signalling.
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Mashup Score: 19Muscle spindle macrophages regulate motor coordination - 2 month(s) ago
Nature Reviews Immunology – Yan et al. report the identification of a population of muscle spindle macrophages, which regulate the muscle stretch reflex through glutamate production.
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Mashup Score: 18Muscle spindle macrophages regulate motor coordination - 2 month(s) ago
Nature Reviews Immunology – Yan et al. report the identification of a population of muscle spindle macrophages, which regulate the muscle stretch reflex through glutamate production.
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Mashup Score: 78
Nature Reviews Immunology – A preprint by Chung et al. presents a framework for the use of transcriptomic and epigenomic data to identify novel transcription factors driving CD8+ T cell states.
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Mashup Score: 02024-oct-Villar-Vesga - 3 month(s) ago
Villar-Vesga et al. (BioRxiv) DOI: 10.1101/2024.09.18.612891 In this preprint, the authors investigate the source of reactive oxygen species (ROS) that determine the severity of multiple sclerosis (MS) in mice. Tissue damage due to ROS production is a key feature in MS. However, the major contributing cells responsible for this damage remain poorly classified. Using multiple human and murine high resolution sequencing data sets, the authors generate an integrated map of brain macrophages and identify an
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How macrophage heterogeneity affects tuberculosis disease and therapy https://t.co/ETJH3FROLx