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Mashup Score: 32Trained immunity in the bone marrow: Hub of autoimmunity - 2 month(s) ago
An inappropriate induction of trained immunity in the bone marrow progenitors of immune cells has been described to underlie chronic inflammatory processes. Mills and colleagues’ recently published paper in Cell Stem Cell shows that maladaptive trained immunity drives inflammation in autoimmune processes, opening a new area of research in autoimmunity.
Source: www.cell.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 11Pilar Alcaide, PhD, to Receive 2025 Outstanding Investigator Award - 4 month(s) ago
The 2025 recipient of the ASIP Outstanding Investigator Award is Dr. Pilar Alcaide, Kenneth and Jo Ann G. Wellner Professor, Director of Tufts Immunology Graduate Program, and Assistant Dean for Faculty Development in the Dep
Source: www.asip.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 12
AbstractBackground and Aims. The distinct functions of immune cells in atherosclerosis have been mostly defined by preclinical mouse studies. Contrastingly
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1The HuMet Repository: Watching human metabolism at work - 6 month(s) ago
Weinisch et al. introduce the HuMet Repository (https://humet.org), a web-based resource for exploring dynamic metabolic responses of healthy subjects to six physiological stimuli, including prolonged fasting, oral glucose/lipid loads, and exercise. The repository enables searching, analyzing, and visualizing time-resolved metabolomics data comprising 2,656 metabolites in human blood, urine, or breath.
Source: www.cell.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 79Phase separation as a new form of regulation in innate immunity - 6 month(s) ago
The discovery of liquid-liquid phase separation as a new form of regulation in innate immunity offers potential for future therapeutic strategies. Wang and Zhou explore recent advances that begin to address the main questions in the field and highlight the functions and principles of phase separation controlling innate immunity.
Source: www.cell.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 40Strategically Focused Research Network (SFRN) Training Program on Inflammatory Cardiovascular Disease (CVD) - 7 month(s) ago
The center, located at Northwestern University Feinberg School of Medicine’s downtown Chicago campus, will advance understanding of the immune cell functions that regulate inflammation in HFpEF using clinical studies, population studies and fundamental experimental systems. It will also develop mechanistic and therapeutic targets for HFpEF, where effective prevention and therapy remain a challenge. Its work will consist of three primary research projects: Clinical: Monocyte inflammatory priming in human
Categories: General Medicine News, CardiologistsTweet
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Mashup Score: 35Strategically Focused Research Network (SFRN) Training Program on Inflammatory Cardiovascular Disease (CVD) - 8 month(s) ago
The center, located at Northwestern University Feinberg School of Medicine’s downtown Chicago campus, will advance understanding of the immune cell functions that regulate inflammation in HFpEF using clinical studies, population studies and fundamental experimental systems. It will also develop mechanistic and therapeutic targets for HFpEF, where effective prevention and therapy remain a challenge. Its work will consist of three primary research projects: Clinical: Monocyte inflammatory priming in human
Categories: General Medicine News, CardiologistsTweet
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Mashup Score: 76Universal recording of immune cell interactions in vivo - 10 month(s) ago
Nature – A paper reports the development of a universal tool for studying cellular interactions in biological systems, and demonstrates its coupling with single-cell transcriptomics methods to…
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 76Universal recording of immune cell interactions in vivo - 10 month(s) ago
Nature – A paper reports the development of a universal tool for studying cellular interactions in biological systems, and demonstrates its coupling with single-cell transcriptomics methods to…
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 2Immunomodulation and immunopharmacology in heart failure - Nature Reviews Cardiology - 12 month(s) ago
In this Review, the authors discuss the clinical and experimental data on immunomodulatory effects of evidence-based treatments for heart failure and their primary mechanisms of action, and highlight potential therapeutic targets and opportunities for the development and application of novel immunomodulatory treatments for heart failure.
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
RT @CellStemCell: Trained immunity in the bone marrow: Hub of autoimmunity https://t.co/n8k11NEGnL