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Mashup Score: 26
Josep Carreras Invited Lecture Dr. Maria Mittelbrunn Immunometabolism and Inflammation Laboratory Centro de Biología Molecular Severo Ochoa (CBMSO). Madrid. “Crosstalk between innate and adaptive immune system during aging”
Source: us06web.zoom.usCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 30Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate - 3 month(s) ago
Nature Communications – Notch signaling is critical for HSC emergence. Here, the authors identify a sub-set of hemogenic endothelial cells with high Notch activity that it is gradually shut down…
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 33Single-cell analysis of the epitranscriptome: RNA modifications under the microscope - 3 month(s) ago
The identification of mechanisms capable of modifying genetic information by the addition of covalent RNA modifications distinguishes a level of complexity in gene expression which challenges key l…
Source: www.tandfonline.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 42Telenotícies - Tractaments epigenètics: a quins pacients amb leucèmia els funcionen i a quins no - 3Cat - 3 month(s) ago
L’equip de Manel Esteller fa servir la tècnica de cèl·lula única per descriure per què uns pacients no hi responen.
Source: www.ccma.catCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 213Esteller pide "salarios dignos" para los investigadores y tiempo... - 3 month(s) ago
El director del programa de Epigenética y Biología del Cáncer del Instituto del Instituto de…
Source: www.infosalus.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 9
Centro de Investigación Biomédica en Red Cáncer
Source: www.ciberonc.esCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 33Investigadores españoles descubren por qué a veces no funcionan algunos fármacos contra el cáncer - 3 month(s) ago
No solo lo que está escrito en nuestro ADN influye en nuestras posibilidades de desarrollar un tumor. Entre otros factores, también todo aquello que regula la expresión de…
Source: www.elmundo.esCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 12Centres CERCA - CERCA - 3 month(s) ago
Més de 13.000 persones treballant a la frontera del coneixement per a fer avançar la societat.
Source: cerca.catCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 32Single-cell Multiomics Analysis of Myelodysplastic Syndromes and Clinical Response to Hypomethylating Therapy - 3 month(s) ago
AbstractAlterations in epigenetic marks, such as DNA methylation, represent a hallmark of cancer that has been successfully exploited for therapy in myeloid malignancies. Hypomethylating agents (HMA), such as azacitidine, have become standard-of-care therapy to treat myelodysplastic syndromes (MDS), myeloid neoplasms that can evolve into acute myeloid leukemia. However, our capacity to identify who will respond to HMAs, and the duration of response, remains limited. To shed light on this question, we have leveraged the unprecedented analytic power of single-cell technologies to simultaneously map the genome and immunoproteome of MDS samples throughout clinical evolution. We were able to chart the architecture and evolution of molecular clones in precious paired bone marrow MDS samples at diagnosis and posttreatment to show that a combined imbalance of specific cell lineages with diverse mutational profiles is associated with the clinical response of patients with MDS to hypomethylating
Source: aacrjournals.orgCategories: General Medicine News, Future of MedicineTweet-
Delighted to introduce the final #open version or our article in Cancer Research Communications @CRC_AACR @AACR showing the longitudinal #singlecell architecture of #myelodysplastic syndrome #MDS upon the use of a #hypomethylating agent https://t.co/2WyMUB4Sep https://t.co/FyEHW0P9D3 https://t.co/gU9Xm9qoti
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Mashup Score: 13
Josep Carreras Distinguished Lecture Prof. Björn Schumacher Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne. “Genome Stability in Aging and Inheritance: New insights from C. elegans”
Source: us06web.zoom.usCategories: General Medicine News, Future of MedicineTweet
If you want to know how our #immune system is affected by #aging, please do not miss today 12.00h @CarrerasIJC Invited Lecture by Dr. Maria Mittelbrunn @MMittelbrunn from the @CBMSO_CSIC_UAM. In our auditorium and online: https://t.co/NXzVeGxTll https://t.co/c0wNBjCBeD