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Mashup Score: 315
Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.
Source: www.cell.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 52Peter MacCallum Cancer Centre - 75 years of world's best cancer care, research and education - 5 month(s) ago
Peter MacCallum Cancer Centre, or Peter Mac as it is known, is Australia’s only publicly funded health service solely dedicated to helping people with cancer…
Source: www.youtube.comCategories: General Medicine News, Hem/OncsTweet-
Celebrating the remarkable Peter MacCallum Cancer Centre - 75 years of world's best cancer care, research and education - @TheDawsonLab is very proud to call this place home @PeterMacCC @PeterMacRes https://t.co/C5Eqq9I1Fu
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Mashup Score: 60Milner Director Tony Kouzarides awarded a knighthood in the King’s Birthday Honours List - The Milner Therapeutics Institute - 7 month(s) ago
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Source: www.milner.cam.ac.ukCategories: General Medicine News, Hem/OncsTweet-
It is hard to encapsulate how much I love @TKLABUK and how much this man has done for me & so many of his trainees - so proud of you mate - deserved recognition! Tony Kouzarides awarded a knighthood https://t.co/w3W8kAixTN
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Mashup Score: 16Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology - 9 month(s) ago
Spatial mapping of mouse and human multiple sclerosis neuropathology at a single-cell resolution unveils the cellular architecture and dynamics underlying disease evolution.
Source: www.cell.comCategories: General Medicine News, Hem/OncsTweet-
👇🏾From @GoCasteloBranco & colleagues - amazing work! Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology: Cell https://t.co/Xc5HEkodM0
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Mashup Score: 68SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway - 11 month(s) ago
Tan et al. use a SLAM-ITseq approach to identify that liver injury stimulates Nrf2-dependent induction of genes in the pentose phosphate pathway (PPP). The Nrf2-driven PPP supports nucleotide biosynthesis to meet the metabolic demands of tissue growth during regeneration.
Source: www.cell.comCategories: General Medicine News, Hem/OncsTweet-
Excited to share our latest manuscript from @TheDawsonLab led by the amazing @vicky__tan in collaboration with @DrAndrewCox @PeterMacRes https://t.co/qcBVt03ue5
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Mashup Score: 79Nuclear export of circular RNA - 11 month(s) ago
Nature – Circular RNAs are exported from the nucleus by Ran-GTP, exportin-2 and IGF2BP1 in a mechanism analogous to protein export rather than mRNA export.
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet-
So thrilled to see this wonderful body of work from Vi Wickramasinghe's lab at @PeterMacRes along with Greg Goodall @CCB_Research - a fundamental discovery with potentially major implications for RNA therapy https://t.co/qkqwnEa7nk
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Mashup Score: 75Nuclear export of circular RNA - 11 month(s) ago
Nature – Circular RNAs are exported from the nucleus by Ran-GTP, exportin-2 and IGF2BP1 in a mechanism analogous to protein export rather than mRNA export.
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet-
So thrilled to see this wonderful body of work from Vi Wickramasinghe's lab at @PeterMacRes along with Greg Goodall @CCB_Research - a fundamental discovery with potentially major implications for RNA therapy https://t.co/qkqwnEa7nk
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Mashup Score: 20Medical research that crosses barriers wins life sciences prize - 1 year(s) ago
A conversation with Raphaël Rodriguez, winner of the Liliane Bettencourt Prize for Life Sciences 2023
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet-
Congratulations to my dear friend the twitterless Raphael Rodriguez @institut_curie Medical research that crosses barriers wins life sciences prize https://t.co/0FiNiWrPwf
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Mashup Score: 35
EQS-News: MorphoSys AG / Key word(s): Study results MorphoSys’ Phase 3 Study of Pelabresib in Myelofibrosis Demonstrates Statistically Significant Improvement in Spleen Volume Reduction and Strong Positive Trend in Symptom Reduction 20.11.2023 / 22:29 CET/CEST The issuer is solely responsible for the
Source: www.morphosys.comCategories: General Medicine News, Hem/OncsTweet-
The BET proteins will always have a special place in my ❤️- so great to see them make a clinical difference in a haematological disease with clinical need. MorphoSys’ Phase 3 Study of Pelabresib in Myelofibrosis https://t.co/qkpAy9n7jO
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Mashup Score: 35
EQS-News: MorphoSys AG / Key word(s): Study results MorphoSys’ Phase 3 Study of Pelabresib in Myelofibrosis Demonstrates Statistically Significant Improvement in Spleen Volume Reduction and Strong Positive Trend in Symptom Reduction 20.11.2023 / 22:29 CET/CEST The issuer is solely responsible for the
Source: www.morphosys.comCategories: General Medicine News, Hem/OncsTweet-
The BET proteins will always have a special place in my ❤️- so great to see them make a clinical difference in a haematological disease with clinical need. MorphoSys’ Phase 3 Study of Pelabresib in Myelofibrosis https://t.co/qkpAy9n7jO
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Why can a human tolerate a drug that globally inhibits transcription? Why do transcription inhibitors not cure cancer? Our first paper of 2025 may help explain (some) of this! So very proud of @DrTobiasW & Ewa Michalak who led the work! https://t.co/f0ZEcIE7eL