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Mashup Score: 3
We are entering an era of gene-based drug approaches that will revolutionize our ability to treat patients with atherosclerotic cardiovascular disease, enabling earlier and more effective interventions. In this EAS webinar, we will examine recent data on RNA-targeting strategies in lipid management and explore therapies based on genome editing with CRISPR/Cas9. Although these treatments are still in development, they hold significant promise for patients with severe dyslipidemias and atherosclerosis. Join us to gain invaluable insights and practical knowledge from two world-renowned experts in the field!
Source: us02web.zoom.usCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 41
Novartis Pharma AG.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
This graph is theoretical, and we need to wait for Lp(a) outcomes trials before we know if the depiction of the arrows is accurate. All evidence to date is Lp(a)-mediated risk is not modifiable by treating other risk factors. See https://t.co/d0txGcA2gs https://t.co/eD5xeDR2k7
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Mashup Score: 1Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation: A Randomized Clinical Trial - PubMed - 2 month(s) ago
ClinicalTrials.gov Identifier: NCT04472676.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
Muvalaplin from Lilly. https://t.co/3xd0IY3Ddq However, until we know where the free apo(a) with its OxPL cargo goes or if it gets into vessels easier, for me, the jury is out if this will be safe and effective. https://t.co/dN5UwUAeKw
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Mashup Score: 172024 Harvest Agourolado High Phenolic Extra Virgin Olive Oil - 2 month(s) ago
RESERVE your bottles of 2024 harvest of Agourolado, high-phenolic extra virgin olive oil from Crete. Only 200 bottles will be produced. This is a PRE-ORDER that will reserve your bottles. All orders will be filled after the harvest this fall, and shipped to you in early to mid December 2024. *** About Agourolado My ver
Source: pappasmarket.comCategories: General Medicine News, CardiologistsTweet-
The Agourolado, Crete Greece- early harvest, high polyphenol Olive Oil is taking orders. ~5000 olives per bottle. I ordered mine. A bit expensive but tasty and theoretically health promoting... https://t.co/7scWkVraEj https://t.co/hWH9kuiXS0
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Mashup Score: 21
In fitting with the American Heart Association’s 100th anniversary of its founding and Arteriosclerosis, Thrombosis and Vascular Biology organizing a Centennial Collection to celebrate this event, lipoprotein(a) [Lp(a)] celebrates its 61st birthday in November 2024. There has been …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
Here are the timelines. If muvalaplin makes it to phase 3, data will be >2030. https://t.co/NrXPcXRs6j https://t.co/HB70jqIY4i https://t.co/GOfr9czRzK
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Mashup Score: 39
DIETARY cholesterol increases the plasma level of total and low-density lipoprotein (LDL) cholesterol and accelerates the development of atherosclerosis and its complications, but individual respon…
Source: www.nejm.orgCategories: General Medicine News, CardiologistsTweet-
BTW, this experiment was published before in 1991. It was done with scientific rigor by measuring sterol synthesis, and showing, in this person, that biliary secretion adaptations prevented increase in plasma cholesterol. https://t.co/xjJJWYbgtE https://t.co/8q2w3czpgE https://t.co/eHRa2od1nx
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Mashup Score: 8Oxidized phospholipids in cardiovascular disease - PubMed - 3 month(s) ago
Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma on apolipoprotein B (apoB)-containing lipoproteins. When initially conceptualized, OxPL-apoB measurement in plasma was expected …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
Oops, here is correct link. https://t.co/mIKddHXHnF https://t.co/axsL5Ca7DV
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Mashup Score: 8Oxidized phospholipids in cardiovascular disease - PubMed - 3 month(s) ago
Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma on apolipoprotein B (apoB)-containing lipoproteins. When initially conceptualized, OxPL-apoB measurement in plasma was expected …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
Oops, here is correct link. https://t.co/mIKddHXHnF https://t.co/axsL5Ca7DV
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Mashup Score: 1Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement - PubMed - 5 month(s) ago
This 2022 European Atherosclerosis Society lipoprotein(a) [Lp(a)] consensus statement updates evidence for the role of Lp(a) in atherosclerotic cardiovascular disease (ASCVD) and aortic valve stenosis, provides clinical guidance for testing and treating elevated Lp(a) levels, and considers its inclu …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
Hopefully they will catch up with EU guidelines.https://t.co/72l5YxxL7V https://t.co/XgYdIZt8XX https://t.co/ANJU3XxX8C
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Mashup Score: 1Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Prespecified Secondary End Points in ORION 1 - PubMed - 5 month(s) ago
URL: https://www.clinicaltrials.gov . Unique identifier: NCT02597127.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
https://t.co/lfD4HvE9cx https://t.co/VZaKYFv3OU https://t.co/zr97Zwux34
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RT @society_eas: 🚨 Only 2 hours left before the webinar starts! This is your last chance to register and join us: https://t.co/h3YhwwpIc8.…