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Mashup Score: 138
Correspondence from The New England Journal of Medicine — Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia
Source: www.nejm.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 131
Correspondence from The New England Journal of Medicine — Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia
Source: www.nejm.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 12Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation - PubMed - 3 month(s) ago
Lp(a)-associated DGs and LPA have a potential role in Lp(a)-induced monocyte inflammation by increasing cytokine secretion and monocyte transendothelial migration. This DG-induced inflammation is, in part, NLRP3 inflammasome dependent.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 5
Composite biomarker factors, representative of the balance between thrombotic and thrombolytic propensity, provided an improvement in predicting stroke/TIA beyond CHA2DS2-VASc score.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 11Increased LL37 in psoriasis and other inflammatory disorders promotes low-density lipoprotein uptake and atherosclerosis - PubMed - 3 month(s) ago
Patients with chronic inflammatory disorders such as psoriasis have an increased risk of cardiovascular disease and elevated levels of LL37, a cathelicidin host defense peptide that has both antimicrobial and proinflammatory properties. To explore if LL37 could contribute to the risk of heart diseas …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 37
Novartis Pharma AG.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 28Particle Number and Characteristics of Lipoprotein(a), LDL, and apoB: Perspectives on Contributions to ASCVD - 4 month(s) ago
Author links open overlay panel Sotirios Tsimikas MD a, Vera Bittner MD, MSPH b Dr Tsimikas is supported by NHLBI grants R01 HL159156 and HL170224; is a co-inventor and receives royalties from patents owned by University of California-San Diego (UCSD); is a co-founder and has an equity interest in Oxitope and Kleanthi Diagnostics; and has a dual appointment at UCSD and Ionis Pharmaceuticals; although these relationships have been identified for conflict-of-interest management based on the overall scope
Source: www.sciencedirect.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 6Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431 239 Patients - PubMed - 4 month(s) ago
APOE genotypes strongly influence Lp(a) and apoB-related lipoprotein levels. This suggests that differences in affinity of apoE proteins for lipoprotein clearance receptors may affect Lp(a) catabolism, suggesting a competition between Lp(a) and apoE protein for similar receptors.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 36Particle Number and Characteristics of Lipoprotein(a), LDL, and apoB: Perspectives on Contributions to ASCVD∗ - 4 month(s) ago
Corresponding Author
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet-
No, we tried to out this in contact in the editorial. The are millions of LDL particles and hundreds of Lp(a) particles, so even though Lp(a0, comparing 1:1 is more atherogenic, the army of LDL particles will overwhelm risk Do both should be treated. https://t.co/TJMIjY2isS https://t.co/1Jfrl1nJr7 https://t.co/zqK1SVDONW
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Mashup Score: 192Particle Number and Characteristics of Lipoprotein(a), LDL, and apoB: Perspectives on Contributions to ASCVD∗ - 4 month(s) ago
Corresponding Author
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
We have new data in todays @NEJM from @ionispharma on volanesorsen reducing pancreatitis events, first time a TG-lowering drug has been shown to reduce risk of pancreatitis. https://t.co/nJipF23lIX https://t.co/41NpNLG3yf