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Mashup Score: 14
Implementation of mobilisation in the ICU was associated with a less than 3% chance of an adverse event occurring and was not found to increase adverse events or mortality overall, providing reassurance for clinicians about the safety of performing this intervention. Subgroup analyses did not clearly identify any specific variable of mobilisation implementation that increased harm.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 18
In patients with acute brain injury, a single ceftriaxone dose decreased the risk of early VAP. On the basis of our findings, we recommend that an early, single dose of ceftriaxone be included in all bundles for the prevention of VAP in patients with brain injury who require mechanical ventilation.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 2US EPA confronts chemical plants’ deadly air pollution - 13 day(s) ago
After nearly two decades, the US Government has finalised long-awaited new limits on toxic air pollution from chemical manufacturing plants, affecting operations at 218 facilities, many of them concentrated along the lower Mississippi River’s “Cancer Alley” (an 137-km-long stretch of chemical manufacturing plants along the lower Mississippi River, populated largely by Black communities) and the Texas Gulf Coast. The US Environmental Protection Agency (EPA) announced the new regulation, under the Clean Air Act, on April 9, 2024.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet-
News: @EPA confronts chemical plants’ deadly air pollution “After nearly 2 decades, the US Government has finalised long-awaited new limits on toxic air pollution from chemical manufacturing plants, affecting operations at 218 facilities” https://t.co/oKw9iU4OPP @BryantFurlow https://t.co/0sjRnOC7eG
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Mashup Score: 1Anne Chang on the burden of chronic respiratory diseases in Indigenous people - The Lancet Respiratory Medicine in conversation with - 15 day(s) ago
Dr Anne Chang discusses the burden of chronic respiratory diseases in Indigenous people.
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Mashup Score: 2
In September 2024, the UN General Assembly will host its second high-level meeting on antimicrobial resistance (AMR). The Global Leaders Group (GLG) on Antimicrobial Resistance has been tasked with supporting preparations for the meeting. On April 4, 2024, the GLG released a new report outlin-ing recommendations to inform discussions at the high-level meeting alongside several proposed targets. An economic study commissioned for the report projected that by 2035, without substantial action on AMR, global life expectancy would drop by 1·8 years, the cost to health care of treating antibiotic resistant infections would reach US$412 billion per year, and productivity losses resulting from AMR would reach $443 billion per year.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 2Lung transplant donors: barriers and ethical considerations - 21 day(s) ago
Last week the ISHLT meeting was held in Prague, Czech Republic, where experts reported on the latest advances in lung transplantation. Findings from the use of robotically assisted surgery for single-lung transplantation were reported from an expert centre in Spain, a procedure where the incision size is reduced thereby decreasing the amount of discomfort, and potentially improving a patient’s recovery time.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 12European Lung Cancer Congress 2024 - 23 day(s) ago
Immune checkpoint inhibitors such as durvalumab plus chemotherapy are first-line treatment for patients with extensive-stage small-cell lung cancer (ES-SCLC), yet durable clinical benefits are not seen for many. As low-dose radiation therapy (LDRT) could induce a priming effect of the immune system, Yan Zhang (West China Medical Center of Sichuan University, Chengdu, China) and colleagues investigated adding LDRT (15 Gy in five daily fractions) to durvalumab plus etoposide–platinum chemotherapy in a single-arm, phase 2 trial (LEAD) of 30 patients with ES-SCLC in China.
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 23UK patient with multidrug-resistant tuberculosis - 24 day(s) ago
In the summer of 2019, Claire (name changed for confidentiality) began to feel unwell. “I felt exhausted all the time”, she explains. “But when I went to my family doctor on two different occasions, I was told fatigue was a complex issue and not given any diagnosis.”
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 78
Our recent study using data from more than 20 million participants has shown that COVID-19 vaccines consistently prevent long COVID symptoms in adults, with meta-analytic calibrated subdistribution hazard ratio (sHRs) of 0·54 (95% CI 0·44–0·67) in CPRD GOLD, 0·48 (0·34–0·68) in CPRD AURUM, 0·71 (0·55–0·91) in SIDIAP, and 0·59 (0·40–0·87) in CORIVA.1 In addition, when considering post-COVID thromboembolic and cardiovascular complications as outcomes of interest, recently published data have shown that vaccination with any COVID-19 first vaccine dose (ChAdOx1, BNT162b2, and mRNA-1273) is associated with reduced risk of post-acute heart failure (0·45 [0·38–0·53] 0–30 days after SARS-CoV-2 infection; 0·61 [0·51–0·73] 91–180 days after SARS-CoV-2 infection), venous thromboembolism (sHR 0·22 [95% CI 0·17–0·29] 0–30 days after SARS-CoV-2 infection; 0·53 [0·40–0·70] 91–180 days after SARS-CoV-2 infection), and arterial thrombosis (0·53 [0·44–0·63] 0–30 days after SARS-CoV-2 infection; 0·72 [0·
Source: www.thelancet.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0Daniel Steinfort and Shankar Siva on radiotherapy field planning in patients with NSCLC - The Lancet Respiratory Medicine in conversation with - 29 day(s) ago
Professor Daniel Steinfort and Professor Shankar Siva discuss the effect of systematic endoscopic mediastinal staging on radiotherapy field planning in patients with locally advanced non-small-cell lung cancer.
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New #OpenAccess Article and the inspiration for this month's cover: Association of active mobilisation variables with adverse events and mortality in patients requiring mechanical ventilation in the ICU: a systematic review and meta-analysis https://t.co/g4Fluw1HC4 https://t.co/XVuL8yZTrY