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Mashup Score: 30Uptake of Sodium-Glucose Cotransporter-2 Inhibitors in Hospitalized Patients With Heart Failure: Insights From the Veterans Affairs Healthcare System - 3 month(s) ago
The use of sodium-glucose cotransporter-2 inhibitors (SGLT2is) in Veterans Affairs (VA) patients hospitalized with heart failure (HF) has not been reported previously.
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Mashup Score: 38Impact as a Metric: Always in Motion - 3 month(s) ago
Impact is defined as “the force of impression of one thing on another: a significant or major effect.” (Merriam-Webster Dictionary)
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Mashup Score: 31
Heart failure (HF) is one of the major challenges of our time given its increase in prevalence and related mortality. Foundational pharmacologic therapies, including angiotensin receptor neprilysin inhibitors (ARNI), beta-blockers, mineralocorticoid receptor antagonists (MRA), and sodium-glucose co-transporter inhibitors (SGLTi), have been established for HF with reduced ejection fraction (HFrEF). Moreover, recent trials have established the role of SGLTi in patients with HF with preserved ejection fraction (HFpEF).
Source: onlinejcf.comCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 31
Heart failure (HF) is one of the major challenges of our time given its increase in prevalence and related mortality. Foundational pharmacologic therapies, including angiotensin receptor neprilysin inhibitors (ARNI), beta-blockers, mineralocorticoid receptor antagonists (MRA), and sodium-glucose co-transporter inhibitors (SGLTi), have been established for HF with reduced ejection fraction (HFrEF). Moreover, recent trials have established the role of SGLTi in patients with HF with preserved ejection fraction (HFpEF).
Source: onlinejcf.comCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 31
Heart failure (HF) is one of the major challenges of our time given its increase in prevalence and related mortality. Foundational pharmacologic therapies, including angiotensin receptor neprilysin inhibitors (ARNI), beta-blockers, mineralocorticoid receptor antagonists (MRA), and sodium-glucose co-transporter inhibitors (SGLTi), have been established for HF with reduced ejection fraction (HFrEF). Moreover, recent trials have established the role of SGLTi in patients with HF with preserved ejection fraction (HFpEF).
Source: onlinejcf.comCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 42Prevalence and Prognostic Implications of Changes in Tricuspid Regurgitation Severity in Acute Heart Failure - 4 month(s) ago
Acute heart failure (AHF) is a leading cause of hospitalization worldwide and adversely affects mortality, frequency of hospitalizations, and the quality of life.1, 2 However, the prognosis of AHF remains poor despite significant developments in the management of chronic heart failure (HF) over the past decades. Secondary tricuspid valve regurgitation (TR) is prevalent among patients hospitalized with AHF. Moreover, concomitant moderate-to-severe TR at admission is associated with a worse prognosis, including all-cause mortality and HF rehospitalization.
Source: onlinejcf.comCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 52
Congestion is one of the major drivers of hospitalization and mortality due to HF and is an important target for treatment [1]. There are a few practical and widely used markers to quantify diuretic efficacy, such as assessment of urinary output or changes in body weight, but they have limitations which may contribute to suboptimal decongestion and subsequent poor outcomes in acute HF. The following three trials presented at ESC-HFA 2024 aimed to identify optimal decongestion strategies.
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Mashup Score: 59Generalizability of the Spectrum of Kidney Risk in the FINEARTS-HF Trial to US Adults with Heart Failure - 7 month(s) ago
Albuminuria (urine albumin-to-creatinine ratio [UACR] ≥30 mg/g) and estimated glomerular filtration rate (eGFR) constitute the basis of contemporary kidney disease staging, and are independently associated with HF onset and progression.1-4 As such, assessment of these complementary domains is important in clinical and research efforts involving the HF population. However, because UACR has been infrequently assessed in HF outcomes trials, generalizability of trial-level kidney risk to real-world HF populations remains uncertain.
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Mashup Score: 17My Journey as a Heart Transplantation Patient…and What I Want Providers to Know—Part III - 8 month(s) ago
JCF is honored to share this Patient Experience Series over the next three weeks. If you have not yet read the first and second parts of this series, you can do so here (https://doi.org/10.1016/j.cardfail.2024.04.005 and https://doi.org/10.1016/j.cardfail.2024.04.006). Part III and final segment of the series is below. The full story will be published in the May 2024 issue and online under our Patient and Caregiver Center at www.jcfonline.com.
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Mashup Score: 21Alcohol consumption and progression of heart failure in those at risk for or with pre-heart failure - 8 month(s) ago
People with heart risk factors such as high blood pressure, diabetes, obesity or high cholesterol, may develop extra strain on the heart over time because of these risk factors. We researched the association of low and moderate-high levels of alcohol intake, compared to no intake, with changes in the heart over time. We found that amongst participants with heart abnormalities, drinking the equivalent of more than a bottle of wine per week was associated with further negative changes in the heart or development of symptoms of heart failure.
Source: onlinejcf.comCategories: General Medicine News, Partners & KOLsTweet
Only 1 out of every 10 patients with HF were discharged on an SGLT2i from the VAs from 2019-2022 🤔 But prescription rates increased from 2% ➡️ 24% over the interval 📈 Read about the factors associated with SGLT2i Rx in this month's #JCF 👇 🔗https://t.co/M5wJVTHkHT https://t.co/XxgG4rNz4I