• Mashup Score: 0
    Streamlining clinical research: an ESMO awareness call to improve sponsoring and monitoring of clinical trials - 1 year(s) ago

    During recent years, the burden of bureaucracy in clinical research has increased dramatically, adversely impacting the activity of investigators and clinical research teams. Although compliance with the Declaration of Helsinki, the guidelines for Good Clinical Practice (GCP), and other applicable regulations remains unquestionable, their overinterpretation and substitution by the internal…

    Source: Annals of Oncology
    Categories: Hem/Oncs, Latest Headlines
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      GarridoLagunaMD

      Agreed. I would add this beautifully written paper from ESMO colleagues. @JlgraciaMD @EmilianoCalvo_ Master piece to understand burden added by CROs to our CTO. A must read. Check their clinical scenarios because we face them every single day https://t.co/UKVjBaMPAi https://t.co/PZzF0swIX7

  • Mashup Score: 1
    Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors - 1 year(s) ago

    PURPOSE Pembrolizumab significantly improves clinical outcomes in advanced/metastatic microsatellite instability high (MSI-H)/deficient mismatch repair (dMMR) solid tumors but is not well studied in the neoadjuvant space. METHODS This is a phase II open-label, single-center trial of localized unresectable or high-risk resectable MSI-H/dMMR tumors. Treatment is pembrolizumab 200 mg once every 3…

    Source: Journal of Clinical Oncology
    Categories: Hem/Oncs, Latest Headlines
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      GarridoLagunaMD

      @MPishvaian @jhatjhmi1 @mkatzmd @FlavioRochaMD @SyedAAhmad5 @JHawksworthMD @NirajGusani @EmilyWinslow4 @drsmags @DrShubhamPant @EileenMOReilly @CentralParkWMD @rachnatshroff @FogacciJoao @pashtoonkasi @TheNotoriousHPB @RachelRiechelm2 @mnoel3232 @JavleMilind @DrHendifar @NbmerchantMD https://t.co/jDiB8rO8FJ Small numbers in non colorectal GI and clearly you can go either way. We don’t have right/wrong here and I would prioritize patient preference. If fit I may perhaps lean towards surgery and we start gathering data re pCR in PDAC.

  • Mashup Score: 2
    Carlos Alcaraz Brilliant Sportsmanship! - 2 year(s) ago

    #Shorts A great display of sportsmanship from Carlos Alcaraz in his Miami semi-final vs Hurkacz! SUBSCRIBE to our channel for the best ATP tennis videos and …

    Source: YouTube
    Categories: Hem/Oncs, Latest Headlines
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      GarridoLagunaMD

      So fun to watch 🎾 Carlos Alcaraz 🇪🇸 Talented, humble and great sportsmanship. This gesture is a must watch for every young kid playing tennis…and some grown ups too 🤣 https://t.co/mAeOacefMa

  • Mashup Score: 1
    Caeleb Dressel and his Jump! - 3 year(s) ago

    Source: YouTube
    Categories: Latest Headlines, Oncologists2
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      GarridoLagunaMD

      Vertical jump by Caleb Dressel he is 6’3’’ so watch where head is and where his feet come. Insane. No wonder he comes to surface one half body ahead of everyone else. His start makes all difference. 👏👏 Manadou vs Dressel Sat final exciting! #Tokyo2020 https://t.co/B5E0u9YrT0