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Mashup Score: 0JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines - 1 hour(s) ago
Synapse formation depends on the coordinated expression and regulation of scaffold proteins. The JNK family kinases play a role in scaffold protein regulation, but the nature of this functional interaction in dendritic spines requires further investigation. Here, using a combination of biochemical methods and live-cell imaging strategies, we show that the dynamics of the synaptic scaffold molecule SAP102 are negatively regulated by JNK inhibition, that SAP102 is a direct phosphorylation target of JNK3, and that SAP102 regulation by JNK is restricted to neurons that harbor mature synapses.
Source: www.jbc.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 7Conference - International Brain Stimulation Conference - About - 23 hour(s) ago
This sixth international meeting, organized by Elsevier and sponsored by and integrated with the journal Brain Stimulation.
Source: www.elsevier.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 6Home Page: IBRO Neuroscience Reports - 7 day(s) ago
IBRO Neuroscience Reports is an Open Access journal which publishes papers describing the results of original research on any aspect of the scientific study of the nervous system. The journal welcomes preliminary, descriptive and small-scale results if they have the potential to stimulate and/or contribute to future research, leading to new insights or hypotheses. The primary criterion for acceptance is that the work is original, scientifically and technically sound, and valuable to the advancement of
Source: www.ibroneuroreports.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 12
This ALBA-IBRO webinar highlights concrete initiatives and programmes, primarily at the institutional level, aimed at closing the gender gap in global brain research.
Source: www.alba.networkCategories: General Medicine News, NeurologyTweet
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Mashup Score: 12
This ALBA-IBRO webinar highlights concrete initiatives and programmes, primarily at the institutional level, aimed at closing the gender gap in global brain research.
Source: www.alba.networkCategories: General Medicine News, NeurologyTweet
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Mashup Score: 5What makes TikTok tick? - How a Neuroscientist Unlocked the Secrets of a Social Media Platform to Communicate Science More Effectively - IBRO - 13 day(s) ago
How a Neuroscientist Unlocked the Secrets of a Social Media Platform to Communicate Science More Effectively
Source: ibro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3Home Page: IBRO Neuroscience Reports - 15 day(s) ago
IBRO Neuroscience Reports is an Open Access journal which publishes papers describing the results of original research on any aspect of the scientific study of the nervous system. The journal welcomes preliminary, descriptive and small-scale results if they have the potential to stimulate and/or contribute to future research, leading to new insights or hypotheses. The primary criterion for acceptance is that the work is original, scientifically and technically sound, and valuable to the advancement of
Source: www.ibroneuroreports.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 7New research provides evidence a high calorie diet could affect mental health in a matter of weeks - IBRO - 17 day(s) ago
New research published in Neuroscience provides evidence that mental health may be impacted by diet surprisingly quickly.
Source: ibro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2
High sensitivity of scotopic vision (vision in dim light conditions) is achieved by the rods’ low background noise, which is attributed to a much lower thermal activation rate (kth) of rhodopsin compared with cone pigments. Frogs and nocturnal geckos uniquely possess atypical rods containing noncanonical cone pigments that exhibit low kth, mimicking rhodopsin. Here, we investigated the convergent mechanism underlying the low kth of rhodopsins and noncanonical cone pigments. Our biochemical analysis revealed that the kth of canonical cone pigments depends on their absorption maximum (λmax).
Source: www.jbc.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 8
There is an urgent need for new or repurposed therapeutics that protect against or significantly delay the clinical progression of neurodegenerative d…
Source: www.sciencedirect.comCategories: General Medicine News, NeurologyTweet
Kunde et al. show that the dynamics of the synaptic scaffold molecule SAP102 are negatively regulated by JNK inhibition. https://t.co/pQKWAop9wv