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Mashup Score: 34HIV Medicine - 6 month(s) ago
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Source: onlinelibrary.wiley.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 18Ultra-processed food is killing us — these two proposals could make a huge difference - 6 month(s) ago
It may seem to you like there is ongoing controversy about whether ultra-processed food (UPF) is really harmful. After all, a press conference last autumn produced head lines reporting that the effects of UPF had been exaggerated and that many UPF products were healthy. In fact the debate is polarised by conflicts of interest. An investigation by the British Medical Journal revealed that four of the five scientists who spoke at the conference had links to UPF companies and the conference itself was
Source: www.standard.co.ukCategories: General Medicine News, Infectious DiseaseTweet-
Article by wonderful @DoctorChrisVT who opened my eyes to horrors of ultra-processed food & unethical influence of food industry (included in my recent talks on HIV & weight - thanks Chris!). Read it! Then buy the book. He's brilliant & this is a crisis. https://t.co/Yx2MENrSTy https://t.co/h02lUFuHlw
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Mashup Score: 37Work with us :: Central and North West London NHS Foundation Trust - 6 month(s) ago
Search here to find a new job, a new career, an opportunity to up skill or to simply change your career direction. Become part of our team. We care for you as much as you care for others. There’s a place for you at CNWL. We’ re passionate about delivering first-class patient-centred, safe and effective care, whether it is in a hospital setting, in a community clinic or in the patient’s own home. Patients are at the heart of everything we do. Providing top quality care depends on our ability to employ the
Source: www.cnwl.nhs.ukCategories: General Medicine News, Infectious DiseaseTweet-
We are delighted to advertise a new consultant post at our incredible HIV service in Central London! Join a wonderful multi-disciplinary team with a dedicated patient network, employed peer support, research, amazing sexual health service & more! https://t.co/rdO0UaSTQ7 Call us! https://t.co/D006oevcnF
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Mashup Score: 12
A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy – Full Text View.
Source: classic.clinicaltrials.govCategories: General Medicine News, Infectious DiseaseTweet-
Doravirine studies with a metabolic focus to watch out for: 1. OPTI-DOR: 1st line DOR/3TC/TDF vs TDF/FTC/DTG in South Africa https://t.co/zNo1dM5c0w 2. ELDORADO: 1st line DOR/3TC/TDF vs TDF/XTC/DTG in S America, Africa & France https://t.co/Qx703kABNN #euhivhep @FrancoisVenter3 https://t.co/iUbQKMwyw8
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Mashup Score: 2Drugs that make HIV-infected cells self-destruct induce profound viral load drops in mice after just one or two doses - 6 month(s) ago
Last month’s Conference on Retroviruses and Opportunistic Infections (CROI 2024) included the latest information about potential drugs and treatments that might lead to a cure. Two presentations included promising data on TACK (targeted activation of cell kill). This is a property of some drugs in the non-nucleoside reverse transcriptase (NNRTI) family which induces a chain of events leading to the self-destruction of HIV-infected cells.
Source: www.aidsmap.comCategories: General Medicine News, Infectious DiseaseTweet-
2/2 @aidsmap also describe TACK very well in this great piece by @guscairns https://t.co/qyAa8b6kA6 #euhivhep
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Mashup Score: 7Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1 - PubMed - 6 month(s) ago
Antiretroviral therapy inhibits HIV-1 replication but is not curative due to establishment of a persistent reservoir after virus integration into the host genome. Reservoir reduction is therefore an important HIV-1 cure strategy. Some HIV-1 nonnucleoside reverse transcriptase inhibitors induce HIV-1 …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Infectious DiseaseTweet-
1/2 Fascinating stuff from Rafael Campo @Merck! Some NNRTI also interfere w late stage HIV replication leading to cell death = targeted activation cell killing (TACK). EFV has mild activity, their novel compound has more You can read more here: https://t.co/2OcOVymBYL #euhivhep https://t.co/MIxlOXem9v
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Mashup Score: 5US Fentanyl Seizures Skyrocket - 6 month(s) ago
Fentanyl seizures in the US increased by 1700% between 2017 and 2023, a new report showed.
Source: www.medscape.comCategories: General Medicine News, Infectious DiseaseTweet-
2/2 Examples that concern me: 1. Fluticasone: we need actual data. 300-fold increase in systemic exposure when administered nasally with ritonavir....surely less with LEN but @hivinteractions advises caution 2. Fentanyl: which is a huge issue in the US https://t.co/SGkDkj5Oge
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Mashup Score: 46
Background Some migrant men who have sex with men (MSM) acquire HIV in France. Aims We investigated, in migrant MSM receiving HIV care in France, the (i) rate of post-migration-HIV acquisition in France, (ii) delay between arrival and HIV acquisition and (iii) factors affecting HIV acquisition within 1 year after migration. Methods This cross-sectional study focused on ≥ 18-year-old MSM born outside France, receiving HIV care in the Paris region. Information on migration history, socioeconomic condition, sexual activity, and health was collected in May 2021–June 2022 through self-administered questionnaires and medical records. Post-migration-HIV-acquisition rate and delay between arrival in France and HIV acquisition were estimated from biographical data and CD4+ T-cell counts. Predictors of HIV acquisition within 1 year after migration were determined using logistic regression. Results Overall post-migration HIV-acquisition rate was 61.7% (715/1,159; 95%CI: 61.2–62.2), ranging from 4
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
62% of MSM with HIV who were not born in France acquired HIV post-migration, 13% in 1st year. 35% left country of birth due to sexuality-related issues. We must do better across Europe but HIV care is often more accessible than prevention.... https://t.co/QMNubeYkEV https://t.co/1g5RYWnvnE
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Mashup Score: 11
This cross-sectional study estimates the incidence of rape-related pregnancies in US states with abortion bans.
Source: jamanetwork.comCategories: General Medicine News, Infectious DiseaseTweet-
>64,000 rape-related pregnancies in 14 US states implementing total abortion bans following the Dobbs decision. I missed this @JAMAInternalMed article, it's sickening. Rape increases HIV acquisition risk & women with HIV experience higher rates of IPV https://t.co/dfNyEG675L https://t.co/MhySZLeTWj
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Mashup Score: 0Increase in HIV incidence in women exposed to rape - 6 month(s) ago
To determine the incidence of HIV acquisition in women postrape compared with a cohort of women who had not been raped.A prospective cohort study.The Rape Impact Cohort Evaluation study based in Durban, South Africa, enrolled women aged 16–40 …
Source: www.ncbi.nlm.nih.govCategories: General Medicine News, Infectious DiseaseTweet-
Even where there are exceptions for rape-related pregnancy, the rape must be reported to the authorities, which most women DO NOT DO. Ref for impact of rape on HIV incidence: https://t.co/N1RXppzoQQ Ref for IPV rates in women with HIV: https://t.co/ZnZxXdN7Hi @BASHH_UK
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Special issue @HIV_Medicine alert! @Esteban09090 & I are overseeing a special issue on 'CVD prevention: statins & beyond'! Read more, & also about current Associate Editor and Review Editor vacancies here: https://t.co/p2jPNg7kbM https://t.co/LURp9AdWNj