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Mashup Score: 3Volume 29, Issue 42 - 1 month(s) ago
eurosurveillance.org is the online home of Eurosurveillance, Europe’s journal on infectious disease surveillance, epidemiology, prevention and control.
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Mashup Score: 8Monkeypox Clade Ib virus introduction into Burundi: first findings, July to mid-August 2024 - 1 month(s) ago
We describe cases with monkeypox virus (MPXV) Clade Ib in Burundi from their first detection in July until 20 August 2024. Testing 442 people with vesicular lesions confirmed 170 cases (98 male; 72 female), 82 (48%) being < 15 years old. Differential diagnosis of the first 30 individuals testing MPXV negative revealed chickenpox in 20. Cases occurred in 26 of 49 Burundi health districts, but mostly in Bujumbura Nord (88/170; 67%). Case-derived MPXV genetic sequences from Burundi and South-Kivu (Democratic Republic of the Congo), clustered together in phylogenetic analysis.
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MPXV negative cases. Of 30 samples, 20 were positive for varicella zoster virus (VZV, mostly children), four samples for herpes simplex virus (HSV)-1,2. Observation ny our collaborator from Burundi who are studying mpox as part of national response https://t.co/1BNH6JxytJ
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Mashup Score: 65
Background Outbreaks of highly pathogenic avian influenza (HPAI) on poultry farms and in wild birds worldwide persists despite intensified control measures. It causes unprecedented mortality in bird populations and is increasingly affecting mammalian species. Better understanding of HPAI introduction pathways into farms are needed for targeted disease prevention and control. The relevance of airborne transmission has been suggested but research involving air sampling is limited and unequivocal evidence on transmission routes is lacking. Aim We aimed to investigate whether HPAI virus from wild birds can enter poultry houses through air inlets by characterising host materials through eukaryote DNA sequencing. Methods We collected particulate matter samples in and around three HPAI-affected poultry farms which were cleared and decontaminated before sampling. Indoor measurements (n = 61) were taken directly in the airflow entering through air inlets, while outdoor air samples (n = 60) were
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
Cool work from our One Health collaborators. @ncoh Detection of airborne wild waterbird-derived DNA demonstrates potential for transmission of avian influenza virus via air inlets into poultry houses, the Netherlands, 2021 to 2022 https://t.co/yz6iz1uRv5
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Mashup Score: 37Orthopoxvirus-specific antibodies wane to undetectable levels 1 year after MVA-BN vaccination of at-risk individuals, the Netherlands, 2022 to 2023 - 2 month(s) ago
In response to the mpox outbreak in 2022 and 2023, widespread vaccination with modified vaccinia Ankara-Bavarian Nordic (MVA-BN, also known as JYNNEOS or Imvanex) was initiated. Here, we demonstrate that orthopoxvirus-specific binding and MVA-neutralising antibodies waned to undetectable levels 1 year post vaccination in at-risk individuals who received two doses of MVA-BN administered subcutaneously with an interval of 4 weeks, without prior smallpox or mpox vaccination. Continuous surveillance is essential to understand the impact of declining antibody levels.
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
waning of antibodies to vaccinia and mpox virus neutralising antibodies 1 year post MVA vaccination. Important to study in the context of questions on vaccine efficacy https://t.co/7kjoL65Sli
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Mashup Score: 59Real-time PCR assay to detect the novel Clade Ib monkeypox virus, September 2023 to May 2024 - 3 month(s) ago
Monkeypox virus (MPXV) is an emerging zoonotic pathogen with complex epidemiology necessitating rapid diagnosis and distinguishing between clades and subclades. The emerging Clade Ib lacks the genomic region used in the Clade I-specific assay from the Centers for Disease Control and Prevention. We report an MPXV real-time PCR to specifically detect Clade Ib. The assay demonstrated proficient sensitivity and specificity in 92 samples and can be included along other TaqMan-based assays to detect MPXV and distinguish between clades and subclades.
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Development and validation of a qPCR specific for clade Ib mpox viruses https://t.co/bxF3SS0Jse @ECDC_EU @CDCgov @EDCTP @DURABLE_EU @WHO
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Mashup Score: 9Note from the editors: WHO declares mpox outbreak a public health emergency of international concern - 3 month(s) ago
eurosurveillance.org is the online home of Eurosurveillance, Europe’s journal on infectious disease surveillance, epidemiology, prevention and control.
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
https://t.co/MBCeG9yk6q
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Mashup Score: 53Real-time PCR assay to detect the novel Clade Ib monkeypox virus, September 2023 to May 2024 - 3 month(s) ago
Monkeypox virus (MPXV) is an emerging zoonotic pathogen with complex epidemiology necessitating rapid diagnosis and distinguishing between clades and subclades. The emerging Clade Ib lacks the genomic region used in the Clade I-specific assay from the Centers for Disease Control and Prevention. We report an MPXV real-time PCR to specifically detect Clade Ib. The assay demonstrated proficient sensitivity and specificity in 92 samples and can be included along other TaqMan-based assays to detect MPXV and distinguish between clades and subclades.
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
Development and validation of a qPCR specific for clade Ib mpox viruses https://t.co/bxF3SS0Jse @ECDC_EU @CDCgov @EDCTP @DURABLE_EU @WHO
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Mashup Score: 18
Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
RT @1986Bom: Peer reviewed manuscript is now also available online: https://t.co/fsTHlmdYau It is very important to continue this work sin…
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Mashup Score: 38Adapting response to a measles outbreak in a context of high vaccination and breakthrough cases: an example from Vaud, Switzerland, January to March 2024 - 5 month(s) ago
A measles outbreak with 51 cases occurred in the canton of Vaud, Switzerland, between January and March 2024. The outbreak was triggered by an imported case, and 37 (72.5%) subsequent cases were previously vaccinated individuals. Epidemiological investigations showed that vaccinated measles cases were symptomatic and infectious. In a highly vaccinated population, it is important to raise awareness among healthcare professionals to suspect and test for measles virus when an outbreak is declared, irrespective of the vaccination status of the patients.
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
A recent outbreak of #measles in the Canton Vaud: With contributions from the Swiss reference laboratory for measles & rubella, located at our Centre @gcevd @hug_ge, thanks & congratulations to Pascal Cherpillod and Francisco Perez-Rodriguez! https://t.co/L7YJvD5g6U
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Mashup Score: 46
Background Some migrant men who have sex with men (MSM) acquire HIV in France. Aims We investigated, in migrant MSM receiving HIV care in France, the (i) rate of post-migration-HIV acquisition in France, (ii) delay between arrival and HIV acquisition and (iii) factors affecting HIV acquisition within 1 year after migration. Methods This cross-sectional study focused on ≥ 18-year-old MSM born outside France, receiving HIV care in the Paris region. Information on migration history, socioeconomic condition, sexual activity, and health was collected in May 2021–June 2022 through self-administered questionnaires and medical records. Post-migration-HIV-acquisition rate and delay between arrival in France and HIV acquisition were estimated from biographical data and CD4+ T-cell counts. Predictors of HIV acquisition within 1 year after migration were determined using logistic regression. Results Overall post-migration HIV-acquisition rate was 61.7% (715/1,159; 95%CI: 61.2–62.2), ranging from 4
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet-
62% of MSM with HIV who were not born in France acquired HIV post-migration, 13% in 1st year. 35% left country of birth due to sexuality-related issues. We must do better across Europe but HIV care is often more accessible than prevention.... https://t.co/QMNubeYkEV https://t.co/1g5RYWnvnE
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RT @Eurosurveillanc: Today's issue 🗞 https://t.co/0YDQH9nqok 🗞 includes three rapid communications on #mpox: 🗺 Authors @ECDC_EU ascerta…