-
Mashup Score: 22Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems - 3 month(s) ago
RBM20 (RNA-binding motif protein 20) is a vertebrate- and muscle-specific RNA-binding protein that belongs to the serine-arginine-rich family of splicing factors. The RBM20 gene was first identified
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 77
BACKGROUND: Pathogenic variants in PKP2 (plakophilin-2) cause arrhythmogenic right ventricular cardiomyopathy, a disease characterized by life-threatening arrhythmias and progressive cardiomyopathy l
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 31The frequency of gene variant reclassification and its impact on clinical management in the inherited arrhythmia clinic - 3 month(s) ago
Genetic testing in the inherited arrhythmia clinic informs risk stratification, clinical management and family screening. Periodic review of variant classification is recommended as supporting evidence accrues over time. However, there is limited reporting of real-world data on the frequency and impact of variant reclassification.
Source: www.heartrhythmjournal.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 104
A molecular autopsy is undertaken in cases of sudden cardiac death with no definitive cause found after conventional autopsy, with the aim of identifying a pathological genetic variant that could account for the death. Greater awareness of malignant arrhythmias in the absence of structural changes in inherited cardiomyopathies has increased the applicability of molecular autopsies, and resulted…
Source: www.nature.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 27The frequency of gene variant reclassification and its impact on clinical management in the inherited arrhythmia clinic - 4 month(s) ago
Genetic testing in the inherited arrhythmia clinic informs risk stratification, clinical management and family screening. Periodic review of variant classification is recommended as supporting evidence accrues over time. However, there is limited reporting of real-world data on the frequency and impact of variant reclassification.
Source: www.heartrhythmjournal.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 2Japan moon landing live: Brace for '20 minutes of terror' as 'sniper' probe attempts historic mission - 4 month(s) ago
Japan is hoping to celebrate becoming the fifth country to land a spacecraft on the moon today. It’s testing experimental technology to attempt a high-precision landing, which Tokyo says is unprecedented if successful. Watch the landing attempt live in the stream below.
Source: news.sky.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 11Effect of Tafamidis on Cardiac Function in Patients With Transthyretin Amyloid Cardiomyopathy - 4 month(s) ago
This post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial examines the effect of tafamidis vs placebo on 30-month changes in cardiac function in patients with transthyretin amyloid cardiomyopathy.
Source: jamanetwork.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 4
Spider measuring record 7.9cm across is almost as big as largest female collected in 2021, which was named Megaspider by Australian Reptile Park
Source: www.theguardian.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 8Aficamten improved outcomes for patients with obstructive hypertrophic cardiomyopathy: Phase 3 SEQUOIA-HCM trial - 4 month(s) ago
USA: The pivotal Phase 3 clinical trial (SEQUOIA-HCM) of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM) has yielded positive results, as announced by
Source: medicaldialogues.inCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 38Toxicology Screening in Sports-Related Sudden Cardiac Death: A Multinational Observational Study - 5 month(s) ago
Knowledge of toxicological findings among sports-related sudden cardiac death (SrSCD) is scarce.This study aimed to describe postmortem toxicology finโฆ
Source: www.sciencedirect.comCategories: General Medicine News, CardiologistsTweet
Great review just online @Circ_Gen Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems! Thanks to Dr Wei Guo and team! @GenPrecisionMed @AHAScience https://t.co/IDFn5J5Hz0 https://t.co/LqlYEbCsa6