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Mashup Score: 20
BACKGROUND: Coronary artery calcium (CAC) is heterogeneous in older age and is incompletely explained by traditional atherosclerotic cardiovascular disease risk factors. The extremes of subclinical atherosclerosis burden are strongly associated with either a low or high 10-year risk of incident atherosclerotic cardiovascular disease, respectively. However, the genetic underpinnings of differences in arterial aging remain unclear. We sought to determine the independent association of 2 polygenic scores for coronary heart disease (CHD) with CAC in adults ≥75 years of age. METHODS: There were 1865 ARIC (Atherosclerosis Risk in Communities) participants who underwent genetic testing at visit 1 (1987–1989) and CAC scans at visit 7 (2018–2019). In the primary analysis, an externally derived multi-ancestry polygenic CHD risk score was calculated for both White and Black participants. Results were confirmed using a separate ARIC-derived polygenic CHD risk score, including ≥6 million variants c
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0CME for Physicians | AHA/ASA Journals - 1 month(s) ago
Not yet an AHA member? The AHA has several membership categories. Join now. You’re reading the articles. Now earn the credit. New CME quizzes posted weekly Earn up to 74 credits annually Improved, 1-click article-to-quiz access from the online table of contents How It Works Join or renew your AHA membership at professional.heart.org. Access to the AHA Journals CME program is included. Read designated journal articles from Circulation, Circulation: Cardiovascular Imaging, and Stroke. Articles are easily
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Mashup Score: 0AHA24 - 1 month(s) ago
Download the mobile program today to easily access event session s, speakers, exhibitors, and organizer messages. Use the native app to personalize your schedule, take notes, share contacts, and more. Build your schedule directly on your computer. Then, install the native app and sync your schedule to your mobile
Source: eppro01.ativ.meCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 1[99mTc]-PentixaTec SPECT/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction | Circulation: Cardiovascular Imaging - 1 month(s) ago
BACKGROUND: Accumulation of CXCR4 (C-X-C motif chemokine receptor 4)–positive immune cells after acute myocardial infarction (AMI) can be visualized by positron emission tomography. For a broader clinical application, there is a need for CXCR4-directed radiotracers labeled with isotopes that can be used with single-photon emission computed tomography (SPECT). We report on the detection of CXCR4 expression after AMI in humans using the novel tracer [99mTc]-PentixaTec. METHODS: In this retrospective analysis, 9 patients with AMI after mechanical revascularization underwent myocardial inflammation imaging with [99mTc]-PentixaTec SPECT/computed tomography and rest perfusion SPECT imaging. Tracer uptake in the infarcted area, spleen, bone marrow, and blood pool were used for semiquantitative analysis and calculation of signal-to-background ratios. The extent and intensity of SPECT-derived inflammatory changes were compared with serological markers and perfusion defects. RESULTS: CXCR4-direc
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0CME for Physicians | AHA/ASA Journals - 1 month(s) ago
Not yet an AHA member? The AHA has several membership categories. Join now. You’re reading the articles. Now earn the credit. New CME quizzes posted weekly Earn up to 74 credits annually Improved, 1-click article-to-quiz access from the online table of contents How It Works Join or renew your AHA membership at professional.heart.org. Access to the AHA Journals CME program is included. Read designated journal articles from Circulation, Circulation: Cardiovascular Imaging, and Stroke. Articles are easily
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 163
BACKGROUND: Accurate assessment of left ventricular filling pressure in patients with atrial fibrillation or flutter (AF) remains difficult. A novel 2-dimensional scoring system, visually assessing time difference between mitral valve and tricuspid valve opening (VMT) score, based on temporal analysis of early diastolic valve opening, could be applied to these patients. We aimed to determine the usefulness of the VMT score in patients with AF. METHODS: We analyzed 119 consecutive patients with AF who underwent cardiac catheterization as a derivation cohort. The diagnostic performance of the VMT score was further evaluated in an external data set containing 189 patients with AF. Elevated left ventricular filling pressure was defined as a mean pulmonary arterial wedge pressure ≥15 mm Hg. The time sequence of atrioventricular valve opening was visually assessed and scored (0, tricuspid valve first; 1, simultaneous; 2, mitral valve first). When the inferior vena cava was dilated, 1 point w
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0CME for Physicians | AHA/ASA Journals - 1 month(s) ago
Not yet an AHA member? The AHA has several membership categories. Join now. You’re reading the articles. Now earn the credit. New CME quizzes posted weekly Earn up to 74 credits annually Improved, 1-click article-to-quiz access from the online table of contents How It Works Join or renew your AHA membership at professional.heart.org. Access to the AHA Journals CME program is included. Read designated journal articles from Circulation, Circulation: Cardiovascular Imaging, and Stroke. Articles are easily
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 0Scientific Sessions - 1 month(s) ago
Join us November 11–13, 2023 for AHA’s Scientific Sessions conference in Philadelphia, PA. This international cardiovascular conference for healthcare professionals is the biggest of the year!
Source: professional.heart.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 16Thin Disguise: Workup of a Left Atrial Appendage Anomaly | Circulation: Cardiovascular Imaging - 1 month(s) ago
View all available purchase options and get full access to this article. File (circcvim-2024-017067-s01.pdf) File (circcvim-2024-017067-s02.mov) File (circcvim-2024-017067-s03.mov) File (circcvim-2024-017067-s04.mov) Request permissions for this article. Department of Cardiovascular Medicine, Atlantic Health, Morristown Medical Center, NJ (R.B., M.W.M.). Department of Cardiovascular Medicine, Hypertrophic Cardiomyopathy Center, Emory Heart and Vascular Center, Atlanta, GA (B.R.W.). Department of Cardiovasc
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3
View all available purchase options and get full access to this article. Request permissions for this article. For Sources of Funding and Disclosures, see page XXX. Correspondence to: Michael DiMaria, MD, University of Michigan, Michigan Medicine, C.S. Mott Children’s Hospital, 1540 E. Hospital Dr, Ann Arbor, MI 48019. Email [email protected] If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Select your manager software from the
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
A single meandering right pulmonary vein with potential systemic arterial fistula. Serial cardiac MRI and 4-D flow characterization offer valuable insights into this rare anatomy and its clinical implications @FontanDoc #AHAJournals @JiwonKimMD @kaznegishi https://t.co/gq6jENBiWC https://t.co/2Z2qqMa5kX
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New analysis from ARIC showed that Polygenic CHD risk is robustly associated with a lower prevalence of CAC=0 and higher prevalence of CAC >1000 in adults >75yo beyond lifestyle & traditional RFs @OmarDzaye @MichaelJBlaha @CiccaroneCenter #AHAJournals https://t.co/YdbGtdviYX https://t.co/KZ70FVZlUF