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Mashup Score: 1
In patients with three or more primary cancers, genetic predisposition explained a significant proportion of cases; however, treatment history, lifestyle habits, and other exposures appeared to play a less significant role. This highlights the value of early genetic screening and the need to develop more sensitive markers of cancer susceptibility.
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Mashup Score: 0OnlineFirst - 4 day(s) ago
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Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0Volume 17 Issue 5 | Cancer Prevention Research | American Association for Cancer Research - 10 day(s) ago
Cancer Prevention Research | 17 | 5 | May 2024
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Mashup Score: 2Award for Outstanding Journal Article | Cancer Prevention Research | American Association for Cancer Research - 13 day(s) ago
Award for Outstanding Journal Article | Cancer Prevention Research | American Association for Cancer Research #aacrcontent {font-size: 16px;} .right { float: right; margin: 0 16px 16px 16px; padding: 16px; width: 220px; background-color: #f0f0f0; border: solid 1px #ddd; } #aacrcontent2 { box-shadow: 3px 3px 6px #ccc, -3px -3px 6px #ccc; font-size: 16px; max-width: 400px; padding: 16px; } .copy h3{margin-top: 20px;} .copy ul { margin-left: 20px; list-style-image:…
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Mashup Score: 0
This study aimed to understand factors affecting miRNA expression, to ensure we create equitable screening tests for ovarian cancer that perform well in diverse populations. The goal is to ensure that we are detecting ovarian cancer cases earlier (secondary prevention) in women of all races, ethnic backgrounds, and socioeconomic means.
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Mashup Score: 5
Abstract. Inflammation is an essential defense mechanism in which innate immune cells are coordinately activated on encounter of harmful stimuli, including pathogens, tissue injury, and toxic compounds and metabolites to neutralize and eliminate the instigator and initiate healing and regeneration. Properly terminated inflammation is vital to health, but uncontrolled runaway inflammation that becomes chronic begets a variety of inflammatory and metabolic diseases and increases cancer risk. Making damaged tissues behave as “wounds that do not heal” and sustaining the production of growth factors whose physiologic function is tissue healing, chronic inflammation accelerates cancer emergence from premalignant lesions. In 1863, Rudolf Virchow, a leading German pathologist, suggested a possible association between inflammation and tumor formation, but it took another 140 years to fully elucidate and appreciate the tumorigenic role of inflammation. Key findings outlined molecular events in t
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Mashup Score: 2An Integrated Cancer Prevention Strategy: the Viewpoint of the Leon Berard Comprehensive Cancer Center Lyon, France - 25 day(s) ago
Abstract. This article describes some of the key prevention services in the Leon Berard Comprehensive Cancer Center (CLB) Lyon, France, which are based on clinical prevention services, outreach activities, and collaboration with professional and territorial health communities. In addition, research is embedded at all stages of the prevention continuum, from understanding cancer causes through to the implementation of prevention interventions during and after cancer. Health promotion activities in the community and dedicated outpatient primary cancer prevention services for individuals at increased risk have been implemented. The CLB’s experience illustrates how prevention can be integrated into the comprehensive mission of cancer centers, and how in turn, the cancer centers may contribute to bridging the current fragmentation between cancer care and the different components of primary, secondary, and tertiary prevention. With increasing cancer incidence, the shift toward integrated pre
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Mashup Score: 2
Breastfeeding for up to 6 months may be associated with lower VPD among women with a BMI < 25 kg/m2. The potential role of MBD in mediating the associations of breastfeeding with breast cancer risk in a select group of women deserves further evaluation.
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Mashup Score: 2COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes - 1 month(s) ago
Nonsteroidal anti-inflammatories (NSAID) are an essential component of any combination chemoprevention of colon cancer. We show NSAID treatment reduces PD-L1 expression on intestinal tumor cells. NSAID regulation of PD-L1 is dependent on COX-2 expression. These data underscore an important immunologic mechanism of action for NSAID in colon cancer prevention.
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Mashup Score: 0Cancer Early Detection | American Association for Cancer Research - 1 month(s) ago
Recent advancements in early cancer detection technologies, particularly blood-based multicancer early detection tests, have progressed rapidly. These
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From the May issue— Triple Primary Cancers: An Analysis of Genetic and Environmental Factors, by Nicholas A. Borja, Mustafa Tekin et al. https://t.co/EtNcHiQQB4 @umiamimedicine https://t.co/4CoVS4gdAv