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Mashup Score: 0
Autoimmune diseases (ADs) represent a heterogenous group of complex diseases with increasing incidence in Western countries and are a major cause of morbidity. Hematopoietic stem cell transplantation (HSCT) has evolved over the last 25 years as a specific treatment for patients with severe ADs, through eradication of the pathogenic immunologic memory and profound immune renewal. HSCT for ADs is…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0
Conditioning with treosulfan and fludarabine (Treo/Flu) has been proven to be feasible and efficient in several types of malignancies before allogeneic hematopoietic stem cell transplantation (allo-HSCT). Given its favorable reduced toxicity profile, we introduced Treo/Flu as conditioning before autologous HSCT (auto-HSCT) in patients with B-cell Non-Hodgkin lymphoma (NHL). The aim of this study…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0
Male-specific late effects after hematopoietic cell transplantation (HCT) include genital chronic graft-versus-host disease (GvHD), hypogonadism, sexual dysfunction, infertility, and subsequent malignancies. They may be closely intertwined and cause prolonged morbidity and decreased quality of life after HCT. We provide a systematic review of male-specific late effects in a collaboration between…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 2
Bone Marrow Transplantation – Rates and predictors of infusion-related reactions in patients receiving standard versus prolonged infusion of rabbit anti-thymocyte globulin for hematopoietic stem…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0
Bone Marrow Transplantation – Addition and drug monitoring of mycophenolate mofetil for GVHD prophylaxis in unrelated bone marrow transplantation
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0
Allogeneic hematopoietic stem cell transplantation (Allo-HCT) remains the only curative treatment for myelofibrosis (MF). Transplantation in patients with MF is mostly done using a reduced intensity conditioning regimen with calcineurin inhibitors for graft versus host disease (GVHD) prophylaxis. Here we sought to evaluate outcomes of patients who underwent an ex vivo CD34+ -selected allo-HCT…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 8
Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication after allogeneic stem cell transplantation (allo-HCT). However, there is no uniform consensus on the optimal strategy for SOS prevention. Ursodeoxycholic acid is the most used regimen, even though its administration is challenging in recipients unable to tolerate oral medication. Defibrotide was recently studied in a phase 3…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0Neutralizing antibody and T cell responses to SARS-CoV-2 vaccination in hematopoietic cell transplant recipients - Bone Marrow Transplantation - 2 year(s) ago
Bone Marrow Transplantation – Neutralizing antibody and T cell responses to SARS-CoV-2 vaccination in hematopoietic cell transplant recipients
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 3
The optimal conditioning regimen for high-risk myelodysplastic syndrome (MDS) patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains elusive. This study aimed to explore the anti-leukemic efficacy and toxicity of Decitabine (Dec, 20 mg/m2/day, day −11 to −7) intensified BUCY2 vs. traditional regimen in high-risk MDS population. We retrospectively evaluated 93…
Source: NatureCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 0
Bone Marrow Transplantation – Endothelial complications after allogeneic stem cell transplantation in patients with pretransplant resolved COVID-19
Source: NatureCategories: Latest Headlines, TransplantationTweet
Hematopoietic stem cell transplantation and cellular therapies for autoimmune diseases: overview and future considerations from the Autoimmune Diseases Working Party (ADWP) of the EBMT @BMTjournal https://t.co/ezjhbyi3j9