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Mashup Score: 32Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C | NEJM - 7 month(s) ago
Original Article from The New England Journal of Medicine — Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C
Source: www.nejm.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 1Engineered bacteria detect tumor DNA - 9 month(s) ago
Bacteria can be engineered to detect human DNA with specific mutations, including ones associated with tumors.
Source: www.science.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Devimistat in Combination with Gemcitabine and Cisplatin in Biliary Tract Cancer: Preclinical Evaluation and Phase Ib Multicenter Clinical Trial (BilT-04) - 10 month(s) ago
AbstractPurpose:. Devimistat (CPI-613) is a novel inhibitor of tumoral mitochondrial metabolism. We investigated the effect of devimistat in vitro and in a phase Ib clinical trial in patients with advanced biliary tract cancer (BTC).Patients and Methods:. Cell viability assays of devimistat ± gemcitabine and cisplatin (GC) were performed and the effect of devimistat on mitochondrial respiration…
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 6
GM-CSF-secreting whole-cell cancer vaccine (GVAX) promotes T-cell response against a range of tumor associated antigens in patients with pancreatic adenocarcinoma (PDA). Here the authors report the results of the initial three treatment arms of a platform trial of neoadjuvant and adjuvant GVAX alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Out in @NatureComms from the @hopkinskimmel team: A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable #PancreaticCancer @DrLizJaffee https://t.co/3A0RkAGZqK
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Mashup Score: 2Advances in Precision Medicine Propel Personalized GI Cancer Care - 12 month(s) ago
Eileen O’Reilly, MD, and Benjamin Weinberg, MD, discuss the importance of conducting biomarker testing as the gastrointestinal cancer treatment arena continues to evolve, the need for increased gene fusion testing, and the negative effects of inadequate biomarker testing in the gastrointestinal cancer population.
Source: OncLiveCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 5Program Guide – ASCO Meeting Program Guide - 12 month(s) ago
AuthorsBenjamin Adam WeinbergRuesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DCBenjamin Adam Weinberg, Hongkun Wang, Xue Geng, Robert K. Suter, Shrayus Sortur, Myra E. Green, Shadi Shokralla, Emily Bakhshi, Krysta Chaldekas, Brent T. Harris, Dionyssia Clagett, John MarshallOrganizationsRuesch Center for the Cure of…
Source: meetings.asco.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
The type of gut bacteria in colorectal cancer tumors varies significantly between younger and older patients, offering a clue toward understanding why cases are rising in people under 45, according to a study due to be presented at next week’s American Society of Clinical Oncology annual meeting.
Source: apple.newsCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 2Early Detection of Circulating Tumor DNA Postoperatively Enables Discovery of Resectable Metastatic Disease in a Patient with Colon Cancer - 1 year(s) ago
Currently, serum carcinoembryonic agent (CEA) along with contrast-enhanced imaging and colonoscopy are used for evaluation of recurrence of colorectal cancer. However, CEA is an unreliable and nonspecific biomarker that may fail to rise and signal relapse. …
Source: PubMed Central (PMC)Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4Off Our Chests - A Book by Dr. John and Liza Marshall - 1 year(s) ago
A breast cancer patient and her colon cancer oncologist husband gain an understanding of the other’s life, a deeper appreciation of what it means to be a cancer patient, and of the emotional strains of being an oncologist in this alternating voice book, Off Our Chests.
Source: Off Our ChestsCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @marshalj23: Liza and I proud to kick it off with a discussion of #offourchests https://t.co/JilTAVL5au
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Mashup Score: 1
Pancreatic adenocarcinoma is associated with a poor prognosis and a 5-year survival rate of 10%. Benjamin Adam Weinberg, MD, Georgetown…
Source: VJOncologyCategories: Hem/Oncs, Latest HeadlinesTweet
RT @mgfakih: Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C | NEJM https://t.co/7UYbrWNhc2 Presidentia…