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Mashup Score: 67Research Specialist – Fritz-Laylin Lab - 4 month(s) ago
Primary Work Address: 1 Campus Center Way, Amherst, MA, 01003-9243 Current HHMI Employees, click here to apply via your Workday account. The Fritz-Laylin Laboratory is looking for a Research Specialist to join their lab at the University of Massachusetts Amherst. Organismal diversity, essential to life as we know it, relies on variability in cell form and function. The Fritz-Laylin laboratory studies the evolution and diversification of the cytoskeleton, an internal scaffolding system that varies wildly among cell types and species, leading to diversity at the organismal level. This work requires understanding the cytoskeletal biology of diverse species, including those from unexplored parts of the tree of life. The Fritz-Laylin lab develops genetic tools to study the cytoskeletal biology of historically neglected lineages, focusing on organisms that occupy pivotal evolutionary positions, exhibit remarkable cytoskeletal biology, and are important for human health and global ecology. To
Source: hhmi.wd1.myworkdayjobs.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 6Career Awards at the Scientific Interface - Burroughs Wellcome Fund - 4 month(s) ago
BWF’s Career Awards at the Scientific Interface (CASI) provide $560,000 over five years to bridge advanced postdoctoral training and the first three years of faculty service. These awards are open to U.S. and Canadian citizens, permanent residents, and temporary residents. The Burroughs Wellcome Fund launched the Career Awards at the Scientific Interface in 1999 to foster the early career development of researchers who are transitioning from training environments in the physical, mathematical, computationa
Source: www.bwfund.orgCategories: General Medicine News, Infectious DiseaseTweet-
RT @BWFUND: Two weeks until the deadline - Career Awards at the Scientific Interface | Deadline Sept. 4, 2024 https://t.co/DAcHBLvI2I #bwfc…
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Mashup Score: 369From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance - 4 month(s) ago
Tackling the challenge created by antibiotic resistance requires understanding the mechanisms behind its evolution. Like any evolutionary process, the evolution of antimicrobial resistance (AMR) is driven by the underlying variation in a bacterial population and the selective pressures acting upon it. Importantly, both selection and variation will depend on the scale at which resistance evolution is considered (from evolution within a single patient to the host population level). While laboratory experiments have generated fundamental insights into the mechanisms underlying antibiotic resistance evolution, the technological advances in whole genome sequencing now allow us to probe antibiotic resistance evolution beyond the lab and directly record it in individual patients and host populations. Here we review the evolutionary forces driving antibiotic resistance at each of these scales, highlight gaps in our current understanding of AMR evolution, and discuss future steps toward evoluti
Source: www.annualreviews.orgCategories: General Medicine News, Infectious DiseaseTweet-
Thrilled to see the first review article from my lab out in advance @AnnualReviews, helmed by @Celia_Sqe: From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance https://t.co/doWuYeZAfb https://t.co/Cdm85PVJeN
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Mashup Score: 412Introducing Axios' Soup Dumpling Index - 5 month(s) ago
It’s the economic indicator most likely to dribble down your chin and onto your shirt.
Source: www.axios.comCategories: General Medicine News, Infectious DiseaseTweet-
RT @amyyqin: Axios' Soup Dumpling Index: How Din Tai Fung prices compare around the world https://t.co/DUABuysog5 https://t.co/DOT1bWL2kN
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Mashup Score: 4
**Chat rolls are on 7am – 9 pm PT from Monday through Sunday.Brooks Falls is on solar power and will be live whenever we have enough sun. Brooks Falls in Ala…
Source: www.youtube.comCategories: General Medicine News, Infectious DiseaseTweet-
This was live, bear cam is a party today https://t.co/1e60IsiUzy
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Mashup Score: 14Directed evolution of material-producing microorganisms | PNAS - 5 month(s) ago
Nature is home to a variety of microorganisms that create materials under environmentally friendly conditions. While this offers an attractive appr…
Source: www.pnas.orgCategories: General Medicine News, Infectious DiseaseTweet-
RT @O_Borkowski: Directed evolution of material-producing microorganisms https://t.co/EkSwVlEicU https://t.co/kzfUzfM7kA
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Mashup Score: 2Wet Leg - Chaise Longue (Official Video) - 5 month(s) ago
Wet Leg – “Chaise Longue” from the album ‘Wet Leg’ out now on DominoSubscribe to Wet Leg on YouTube: http://smarturl.it/WetLegYT Order ‘Wet Leg’ Here: https:…
Source: www.youtube.comCategories: General Medicine News, Infectious DiseaseTweet-
Now listening to https://t.co/8Uo93H6Dxm
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Mashup Score: 6A conjugative plasmid exploits flagella rotation as a cue to facilitate its transfer - 5 month(s) ago
Conjugation-mediated DNA delivery is the primary mode for antibiotic resistance spread; yet, molecular mechanisms regulating the process remain largely unexplored. While conjugative plasmids typically rely on solid surfaces to facilitate donor-to-recipient proximity, the pLS20 conjugative plasmid, prevalent among Gram-positive Bacillus spp., uniquely requires fluid environments to motivate its transfer. Here we unveiled that pLS20, carried by B. subtilis, induces adhesin-promoted multicellular clustering, which can accommodate various species, offering a stable platform for DNA delivery in liquid milieu. We further discovered that induction of pLS20 promoters, governing crucial conjugative genes, hinges on the presence of donor cell flagella, the major bacterial motility organelle. Moreover, pLS20 regulatory circuit is strategically integrated into a mechanosensing signal transduction pathway responsive to flagella rotation, harnessing propelled flagella to activate conjugation genes e
Source: www.biorxiv.orgCategories: General Medicine News, Infectious DiseaseTweet-
RT @biorxiv_micrbio: A conjugative plasmid exploits flagella rotation as a cue to facilitate its transfer https://t.co/cC3amgcinp #biorxiv…
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Mashup Score: 41
Nature – A programmable RNA that bridges a genetic donor and a target could herald a safer and more flexible approach to large-scale chromosome changes.
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet-
RT @DamonLisch: It is a really good idea to fund basic research on transposable elements. https://t.co/JvFIm0VZCd
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Mashup Score: 3
Cooluli 20L Mini Fridge For Bedroom – Car, Office Desk & College Dorm Room Glass Front Digital Temperature Control 12v Small Refrigerator for Food, Drinks, Skin Care, Beauty Breast Milk (Blue)
Source: www.amazon.comCategories: General Medicine News, Infectious DiseaseTweet-
Fridge: https://t.co/8lRCFTftAw Fans: https://t.co/ncLvpVs72i Wiring Harnesses (polarity needs to be reversed): https://t.co/sYJTxpkxoz
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RT @FritzLaylin: 📢We are hiring a microscope specialist! Please apply and/or spread the word! https://t.co/OIAaGDtBhc