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Mashup Score: 2
DS Cohort Study/Women’s Interagency HIV Study Combined Cohort Study (MWCCS) who had initiated ART between 1999 and 2020 and had a suppressed HIV viral load (≤200 copies/ml) within 1 year of ART initiation. We compared the frequency of incident HIV viremia (HIV-1 RNA >200 copies/ml) between adult PWH with and without DM. Poisson regression was used to examine the rate of incident viremia based on the diagnosis of DM among PWH. DM was defined as two consecutive fasting glucose measurements ≥126 mg/dl, use of antidiabetic medications, preexisting DM diagnosis, or a confirmed HbA1c >6.5%. Results: 1061 women (112 with DM, 949 without DM) and 633 men (41 with DM, and 592 without DM) were included in the analysis. The relative rate (RR) of incident HIV viremia for women with HIV and DM was lower when compared to women without DM (0.85 [95% CI: 0.72–0.99]; P = 0.04). The RR of incident viremia for women with uncontrolled DM (HbA1c > 7.5%) was higher when compared to women with controlled DM (
Source: journals.lww.comCategories: General Medicine News, HIV/AIDSTweet
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Mashup Score: 3
ethods: We included adult PWH during routine visits from October 2022 to February 2023. The BES questionnaire was administered with the support of a psychiatrist (score <17 binge eating very unlikely, binge eating ≥17 possible/very likely). We performed a logistic regression for the binary outcome BES at least 17 and being overweighted/obese as effect measure of risk association, and then adjusted for possible confounders (as integrase inhibitor exposure) and performed a sensitivity analysis fitting the regression model including and excluding depression (which may drive binge eating). Results: We included 1204 PWH, 75.2% men, median age 53 years [interquartile range (IQR): 44–60], 95.6% with undetectable HIV-RNA. As for BMI, we had overweight and obesity in 35.1 and 19.4% cases. Considering BES, 1089 (90.4%) PWH had a score less than 17, 115 (9.6%) at least 17. Multivariable analysis showed that obesity [odds ratio (OR) = 6.21, P < 0.0001), overweight (OR = 2.21, P = 0.006) and depres
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
A large Italian study has – for the first time – shown that a significant proportion of overweight/obese people with #HIV infection suffer from binge eating, and may need tailored support to manage their weight. @UniPadova 🔗➡️ https://t.co/NXPNIBMLkg https://t.co/TEWzKnnDsY
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Mashup Score: 1Wolters Kluwer Health - 17 day(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
In a Baltimore (US) cohort of people living with HIV (PLHIV) @LaurenZalla @leskocar et al. found moderate to severe anxiety was prevalent & associated with viral non-suppression, indicating the need to expand anxiety treatment for PLHIV. https://t.co/jrjSAGtfyk @JohnsHopkinsEPI https://t.co/Isge6rLDv0
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Mashup Score: 1
o de Janeiro, Brazil. Design: Analysis of data from a randomized controlled trial and retrospective cohort study. Methods: We analyzed data from two studies conducted between 2005 and 2017. The THRio Study (2005–2012) evaluated increasing tuberculin skin testing (TST) and TB preventive therapy (TPT) and UnivART (2010–2017) was a virtual cohort study of people with HIV and TB with data from four national electronic registries. Results: Among 4,606 people with HIV in THRio, 2,992 (65.0%) had a TST placed and read, of whom 312/1,865 (17%) males and 203/1,127 (18%) females (p = 0.37) had prevalent TB infection. TB disease incidence was higher among males compared to females overall (IRR 1.33, 95% CI 1.04–1.69), among males compared to females who did not receive TPT (IRR 1.30, 95% CI 1.01–1.67), and among males compared to females on ART (IRR 1.64, 95% CI 1.17–2.29). Among 54,957 people with HIV in UnivART, TB disease incidence rates were higher among males than females overall (IRR 1.28,
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
RT @TAGHIVscience: Sex differences in #tuberculosis infection and disease among people with #HIV https://t.co/sdAA7iuiye (subscription req…
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Mashup Score: 3Addressing methamphetamine use in persons with HIV : AIDS - 1 month(s) ago
An abstract is unavailable.
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
Authors conclude treatment of methamphetamine use should be integrated into routine care. Please also visit the link below to read an Editorial Comment on this paper from @Esteban09090 and David Dorfman for further insights. 📖🔗https://t.co/2qvEs9GZP0
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Mashup Score: 6Impact of methamphetamine use on HIV and other health... : AIDS - 1 month(s) ago
Methods: We conducted a retrospective chart review to characterize methamphetamine use among 3092 PWH at an urban HIV Medicine clinic between July 1, 2022 and June 30, 2023. The chi-squared test was utilized to assess for statistically significant differences in demographics and HIV and other health outcomes among PWH who use and do not use methamphetamine. Results: The prevalence of methamphetamine use among PWH in this cohort was 17%. PWH who used methamphetamine were more likely to be <40 years of age, identify as White race, live in neighborhoods with low Healthy Places Index scores, identify as lesbian, gay, or bisexual, report male sex with men (MSM), MSM and injection drug use (IDU), or IDU as HIV transmission risk factor, miss scheduled HIV primary care visits, and screen positive for hepatitis C virus antibody, gonorrhea, chlamydia, and major depressive disorder. PWH who use methamphetamine were also less likely to be virally suppressed and have a CD4+ cell count ≥200 cells/mm
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
Bamford et al show in the current issue of @AIDS, 20% of 3,000 PWH at an urban clinic report methamphetamine use; recent use is more likely among <40 yrs, Caucasian individuals with higher VL and an ⬆️ incidence of STIs. Read this paper here: https://t.co/GVtRoh4CTf 🧵⬇️
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Mashup Score: 1Concordance between daily diary reported pre-exposure... : AIDS - 1 month(s) ago
n Amsterdam, the Netherlands (2015–2020). Methods: Participants could record their PrEP intake in a diary app. Dried blood spots (DBS) were taken at 6, 12, 24, and 48 months and analysed for tenofovir diphosphate (TFV-DP) and emtricitabine triphosphate (FTC-TP) concentrations. We included TFV-DP measurements preceded by diary completion on at least 90% of days in the 6 weeks prior. We examined the association between self-reported PrEP intake (i.e. number of pills) and TFV-DP concentrations using tobit regression with a random intercept per participant. We also calculated concordance between categorized PrEP intake (i.e. <2, 2–3, 4–6 or 7 pills per week) and categorized TFV-DP concentrations (i.e. <350, 350–699,700–1249 or ≥1250 fmol/punch) using weighted Cohen's kappa. Last, we calculated concordance between self-reported recent PrEP intake (yes/no, in past 2 days) and quantifiability of FTC-TP (yes/no) using Cohen's kappa. Results: Seven hundred and fifty-nine DBS measurements from 2
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
Concordance between daily diary reported pre-exposure prophylaxis intake and intraerythrocytic tenofovir diphosphate in the Amsterdam Pre-exposure Prophylaxis demonstration project Read here: https://t.co/Kc4twEvzcN Thank you @ElskeHoornenbor et al. @GGDAmsterdam @GGDAmsID https://t.co/XmQtT78W5f
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Mashup Score: 0Explaining racial and ethnic disparities in antiretroviral... : AIDS - 2 month(s) ago
2017–2021 cycles of the Medical Monitoring Project. Methods: Among MSM taking ART, we calculated prevalence differences (PDs) with 95% confidence intervals (CIs) of ART adherence (100% ART adherence, past 30 days) and SVS (all viral loads in past 12 months <200 copies/ml or undetectable) for Black MSM (BMSM) and Hispanic/Latino MSM (HMSM) compared with White MSM (WMSM). Using forward stepwise selection, we calculated adjusted PDs with 95% CIs to examine if controlling for selected variables reduced PDs. Results: After adjusting for age, any unmet service need, federal poverty level (FPL), food insecurity, homelessness, time since HIV diagnosis, gap in health coverage, and education, the BMSM/WMSM PD for ART adherence reduced from −16.9 to −8.2 (51.5%). For SVS, the BMSM/WMSM PD reduced from −8.3 to −3.6 (56.6%) after adjusting for ART adherence, age, homelessness, food insecurity, gap in health coverage, FPL, any unmet service need, time since diagnosis, and ER visit(s). The HMSM/WMSM
Source: journals.lww.comCategories: General Medicine News, Infectious DiseaseTweet-
#2. Explaining racial and ethnic disparities in antiretroviral therapy adherence and viral suppression among U.S. men who have sex with men 🔗 https://t.co/g7MljA9PMw #3. Distinct anal microbiome is correlated with anal cancer precursors in MSM with HIV 🔗https://t.co/gcVIH8GdRF
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Mashup Score: 3The impact of HIV preexposure prophylaxis on bacterial... : AIDS - 2 month(s) ago
ubMed, Embase, and Scopus without language restrictions until 1 February 2023. We sought studies reporting data for the estimation of incidence rate ratios (IRR), prevalence ratios or cumulative incidence ratios (the latter in equal time periods before and after PrEP initiation) regarding bacterial STI occurrence. Separate analyses were performed overall for any STI, syphilis, chlamydia and gonorrhea (overall; rectal; urethral; pharyngeal for the two latter conditions); ratios greater than unity denoted increase in STI occurrence after PrEP initiation. Results: Twenty-three eligible studies with 11 776 participants (age range: 18–71 years) with a median follow-up of 12 months were included. Overall, PrEP initiation was associated with a significant increase in the occurrence of any STI (pooled effect size: 1.15, 95% confidence interval (CI): 1.04–1.26), any gonorrhea (pooled effect size: 1.17, 95% CI: 1.02–1.34), any chlamydia (pooled effect size: 1.31, 95% CI: 1.09–1.58) and rectal ch
Source: journals.lww.comCategories: General Medicine News, HIV/AIDSTweet-
June is out! Read this review by @georgiadisnk @TheodoreLytras @DeanPNHalkitis @TSergentanis et al. which shows PrEP use among MSM is associated with an increase in STIs, underlining the importance of systematic STI screening among this group. 🔗➡️https://t.co/SE0OA9vrC4
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Mashup Score: 0
An abstract is unavailable.
Source: journals.lww.comCategories: General Medicine News, HIV/AIDSTweet-
The authors conclude personalized Medicine Management is required to reduce use of AC/ sedative meds. Karl Goodkin, @Esteban09090 et al. have also written a commentary on this paper. You can read this at the link below: ➡️🔗https://t.co/0rMJiHjwBP #AIDS
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This cohort study finds, amongst women with good adherence to ART, those with #diabetes mellitus are less likely to experience episodes of viraemia than their non-diabetic counterparts. Further research is needed to explain this observation. 🔗 https://t.co/ucUJ2na1Mz https://t.co/cLVO0TmA7c